Erschienen in:
01.12.2001 | Adis New Formulation Profile
Cetirizine/Pseudoephedrine
A Viewpoint by K. Kontou-Fili
verfasst von:
K. Kontou-Fili
Erschienen in:
Drugs
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Ausgabe 15/2001
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Excerpt
Cetirizine 5mg in combination with pseudoephedrine hydrochloride sustained-release 120mg was developed in order to provide more efficient and prompt relief of rhinitis symptoms. Double-blind, placebo-controlled clinical trials involving close to 900 patients experiencing seasonal or perennial allergic rhinitis have demonstrated that cetirizine plus pseudoephedrine controls most naso-ocular symptoms to a greater extent than either component alone; nasal congestion, a symptom usually unaffected by antihistamine H1 antagonists alone, was significantly reduced in patients with perennial allergic rhinitis. …