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Clinical and Experimental Medicine

Clinical and Experimental Medicine OnlineFirst articles

15.02.2018 | Review Article Open Access

The role of the alternative pathway of complement activation in glomerular diseases

The complement system (CS) has recently been recognized as a bridge between innate and adaptive immunity that constitutes a very complex mechanism controlling the clearance of pathogens, cellular debris, and immune complexes. Out of three known …

14.02.2018 | Original Article

Clinical significance of circulating tumor cells from lung cancer patients using microfluidic chip

Circulating tumor cells (CTCs) exist in the peripheral blood and have an important role in the disease development, tumor metastasis and clinical surveillance, especially in the process of metastasis. However, the technology of detecting CTCs …

12.02.2018 | Original Article

Kallikrein-related peptidase 6 (KLK6) expression differentiates tumor subtypes and predicts clinical outcome in breast cancer patients

Novel molecular markers that address the heterogeneity of breast cancer (BC) and provide meaningful prognostic information for BC patients are needed. Kallikrein-related peptidase 6 (KLK6) is aberrantly expressed and functionally implicated in BC …

07.02.2018 | Original Article Open Access

Plasma clot formation and clot lysis to compare effects of different anticoagulation treatments on hemostasis in patients with atrial fibrillation

The effect of direct oral anticoagulants (DOACs) on turbidimetric measurements of plasma clot formation and susceptibility to fibrinolysis may facilitate a comparison between different classes of anticoagulants in plasma samples. We obtained 424 …

02.02.2018 | Original Article Open Access

Is the 1298A>C polymorphism in the MTHFR gene a risk factor for arterial ischaemic stroke in children? The results of meta-analysis

An elevated level of homocysteine is a risk factor for vascular diseases, brain atrophy and several other disorders. The 1298A>C polymorphism (rs1801131) leads to mildly decreased MTHFR activity. Previously, it was observed that the MTHFR 1298A>C …

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Über diese Zeitschrift

Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hematology, immunology, oncology and virology. The major criteria for publication will be clarity, experimental soundness and advances in knowledge. Papers containing new clinical or experimental data, or which are likely to contribute to changes in clinical practice or in thinking about a disease will be given priority due to their immediate importance.
The following types of articles will be considered for publication: invited or unsolicited Reviews and Editorials; Original papers; Short communications; Letters to the Editor. Submission of case reports, clinical trials and epidemiological studies is not encouraged. The Editor-in-Chief will under certain circumstances consider for publication monothematic issues and supplements devoted to congress proceedings.

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