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Clinical and Experimental Medicine

Clinical and Experimental Medicine OnlineFirst articles

25.02.2020 | Review Article

Patient-derived xenograft models for personalized medicine in colorectal cancer

Establishing superior preclinical models is critical for translational cancer research owing to the high failure rates of novel therapeutics in clinical studies. Even though cell line-derived xenograft models are easy to create, they have numerous …

20.02.2020 | Original Article

Risk factors for treatment resistance and relapse of Chinese patients with MPO-ANCA-associated vasculitis

Identification of risk factors for treatment resistance and relapse would be crucial to personalization therapy in patients with myeloperoxidase (MPO)-anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (MPO-AAV). Current evidence …

20.02.2020 | Original Article Open Access

Pentraxin-3 is not related to disease severity in cirrhosis and hepatocellular carcinoma patients

The acute-phase protein pentraxin-3 (PTX3) is a component of the innate immune system. Inflammation and tissue injury increased PTX3 in the injured liver, and accordingly, circulating PTX3 was induced in patients with chronic liver diseases. In …

19.02.2020 | Original Article

Viral clearance ameliorates hematological and inflammatory markers among diabetic patients infected with hepatitis C genotype 4

The achievement of virological response in the treatment of hepatitis C virus (HCV) can improve the extrahepatic manifestations. The present study aimed to investigate the effect of HCV eradication after sofosbuvir/daclatasvir (SOF/DCV) therapy on …

17.02.2020 | Case Report

Extramedullary blastic transformation of primary myelofibrosis in the form of disseminated myeloid sarcoma: a case report and review of the literature

Splenomegaly is a key clinical manifestation of myelofibrosis, and splenectomy is currently indicated in patients with drug refractory, symptomatic splenomegaly or with the aim of improving refractory cytopenias. Transformation to acute myeloid …

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Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hematology, immunology, oncology and virology. The major criteria for publication will be clarity, experimental soundness and advances in knowledge. Papers containing new clinical or experimental data, or which are likely to contribute to changes in clinical practice or in thinking about a disease will be given priority due to their immediate importance.
The following types of articles will be considered for publication: invited or unsolicited Reviews and Editorials; Original papers; Short communications; Letters to the Editor. Submission of case reports, clinical trials and epidemiological studies is not encouraged. The Editor-in-Chief will under certain circumstances consider for publication monothematic issues and supplements devoted to congress proceedings.

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