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Clinical and Experimental Medicine

Clinical and Experimental Medicine OnlineFirst articles

07.06.2019 | Original Article

Functional polymorphisms of the receptor for the advanced glycation end product promoter gene in inflammatory bowel disease: a case–control study

The receptor for the advanced glycation end products (RAGE) is a multiligand transmembrane receptor involved in chronic inflammation whose specific polymorphisms of the promoter gene were found to increase its transcriptional activity. We …

24.05.2019 | Short Communication Open Access

Neutrocyte-to-lymphocyte ratio predicts the presence of a replicative hepatitis C virus strand after therapy with direct-acting antivirals

Residual HCV-RNA can persist in liver tissue and peripheral blood mononuclear cells (PBMCs) long after antiviral therapy of chronic hepatitis C in patients repeatedly negative for viral RNA in serum. This occult infection associates with impaired …

20.05.2019 | Original Article

Changes in APRI and FIB-4 in HBeAg-negative treatment-naive chronic hepatitis B patients with significant liver histological lesions receiving 5-year entecavir therapy

According to guidelines, antiviral therapy for adults with immune-active chronic hepatitis B (CHB) should be adopted to decrease the risk of liver-related complications. Fibrosis assessment during antiviral treatment is a key step in antiviral …

18.05.2019 | Original Article

Circulating soluble levels of MIF in women with breast cancer in the molecular subtypes: relationship with Th17 cytokine profile

Breast cancer (BC) is a health problem worldwide; there is evidence that inflammatory cytokines are increased in BC. Macrophage migration inhibitory factor (MIF) has multiple effects on immune cells, inflammation and cancer. Besides, in previous …

15.05.2019 | Original Article

Anti-domain 1 of beta2-glycoprotein I aids risk stratification in lupus anticoagulant-positive patients

Lupus anticoagulant (LA) is considered a risk factor for thromboembolism (TE) and adverse pregnancy outcomes (APOs). However, quite a few patients diagnosed with LA positivity do not suffer these adverse events. Further testing of anticardiolipin …

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Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hematology, immunology, oncology and virology. The major criteria for publication will be clarity, experimental soundness and advances in knowledge. Papers containing new clinical or experimental data, or which are likely to contribute to changes in clinical practice or in thinking about a disease will be given priority due to their immediate importance.
The following types of articles will be considered for publication: invited or unsolicited Reviews and Editorials; Original papers; Short communications; Letters to the Editor. Submission of case reports, clinical trials and epidemiological studies is not encouraged. The Editor-in-Chief will under certain circumstances consider for publication monothematic issues and supplements devoted to congress proceedings.

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