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Clinical and Experimental Medicine

Clinical and Experimental Medicine OnlineFirst articles

18.05.2018 | Original Article Open Access

Synergistic effect of TRAIL and irradiation in elimination of glioblastoma stem-like cells

Glioblastoma multiforme (GBM) is the most common malignancy in central nervous system. A small subpopulation of GBM cells known as GBM stem-like cells (GSLCs) were supposed to be the most malignant cells among GBM cells as they are resistant to …

10.05.2018 | Letter to the Editor

The humoral immunity to epidermal and dermal antigens in psoriasis: a downstream rather than an upstream event

The presence of immunoglobulin G (IgG) and complement in upper epidermis of psoriatic skin lesions has been reported for more than 40 years [ 1 , 2 ]. Recently, a number of antigenic proteins have been observed in psoriatic skin lesions, in …

10.05.2018 | Original Article Open Access

Droplet digital PCR detects high rate of TP53 R249S mutants in cell-free DNA of middle African patients with hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is still a major killing malignancy in sub-Saharan Africa. Lifelong intoxication with aflatoxin B1 is considered as one of the primary causes of this situation. The role of aflatoxin in HCC from a given population is …

25.04.2018 | Original Article

Longitudinal monitoring of liver fibrosis status by transient elastography in chronic hepatitis B patients during long-term entecavir treatment

The correlation between improvement in longitudinal liver stiffness and fibrosis regression has not been properly evaluated during long-term antiviral therapy in chronic hepatitis B (CHB) patients. In this study, liver stiffness was serially …

11.04.2018 | Original Article

Metabolic syndrome and the decreased levels of uric acid by leflunomide favor redox imbalance in patients with rheumatoid arthritis

Oxidative stress plays a role in the pathophysiology of rheumatoid arthritis (RA). The aim of the present study was to verify the influence of metabolic syndrome (MetS) and disease-modifying antirheumatic drugs on nitrosative and oxidative …

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Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hematology, immunology, oncology and virology. The major criteria for publication will be clarity, experimental soundness and advances in knowledge. Papers containing new clinical or experimental data, or which are likely to contribute to changes in clinical practice or in thinking about a disease will be given priority due to their immediate importance.
The following types of articles will be considered for publication: invited or unsolicited Reviews and Editorials; Original papers; Short communications; Letters to the Editor. Submission of case reports, clinical trials and epidemiological studies is not encouraged. The Editor-in-Chief will under certain circumstances consider for publication monothematic issues and supplements devoted to congress proceedings.

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