Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 5/2014

01.11.2014 | General Gynecology

Clinical characteristics and treatment of Herlyn–Werner–Wunderlich syndrome

verfasst von: Jinhui Wang, Lan Zhu, Jinghe Lang, Zhufeng Liu, Dawei Sun, Jinhua Leng, Qingbo Fan

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 5/2014

Einloggen, um Zugang zu erhalten

Abstract

Objective

To investigate the clinical characteristics and treatment of the Herlyn–Werner–Wunderlich syndrome (HWWS).

Methods

Sixty-one patients diagnosed with HWWS were retrospectively analyzed. HWWS is categorized into three types in China.

Results

Age at presentation of all the cases was after menarche. The most common clinical presentations were dysmenorrhea for type I and vaginal discharge for types II and III. Clinical presentations of types II and III may not occur until reproductive age. HWWS occurred on the right in 39/61. Excision of the obstructed vaginal septum was the treatment utilized in this cohort. After surgery, subsequent pregnancies were ipsilateral in 52.9 %.

Conclusions

Clinical presentation in untreated HWWS suggests the anatomic anomaly. Early recognition and treatment can reduce symptoms. Pregnancies occur in both the affected and unaffected uterus.
Literatur
1.
Zurück zum Zitat Orazi C, Lucchetti MC, Schingo PMS et al (2007) Herlyn–Werner–Wunderlich syndrome: uterus didelphys, blinding hemivagina and ipsilateral renal agenesis. Sonographic and MR findings in 11 cases. Pediatr Radiol 37:657–665PubMedCrossRef Orazi C, Lucchetti MC, Schingo PMS et al (2007) Herlyn–Werner–Wunderlich syndrome: uterus didelphys, blinding hemivagina and ipsilateral renal agenesis. Sonographic and MR findings in 11 cases. Pediatr Radiol 37:657–665PubMedCrossRef
2.
Zurück zum Zitat Purslow CE (1922) A case of unilateral haematocolpos, haematometra and haematosalpinx. J Obstet Gynaecol Br Emp 29:643CrossRef Purslow CE (1922) A case of unilateral haematocolpos, haematometra and haematosalpinx. J Obstet Gynaecol Br Emp 29:643CrossRef
3.
Zurück zum Zitat Bian ML, Huang RL, Wu BZ, Lian LJ, Song HZ (1985) Oblique vaginal septum: report of 15 cases. Zhonghua Fu Chan Ke Za Zhi 20(2):85–88PubMed Bian ML, Huang RL, Wu BZ, Lian LJ, Song HZ (1985) Oblique vaginal septum: report of 15 cases. Zhonghua Fu Chan Ke Za Zhi 20(2):85–88PubMed
4.
Zurück zum Zitat O’Neill MJ, Yoder IC, Connolly SA, Mueller PR (1999) Imaging evaluation and classification of developmental anomalies of the female reproductive system with an emphasis on MR imaging. AJR Am J Roentgenol 173(2):407–416PubMedCrossRef O’Neill MJ, Yoder IC, Connolly SA, Mueller PR (1999) Imaging evaluation and classification of developmental anomalies of the female reproductive system with an emphasis on MR imaging. AJR Am J Roentgenol 173(2):407–416PubMedCrossRef
5.
Zurück zum Zitat Takagi H, Matsunami K, Imai A (2010) Uterovaginal duplication with blind hemivagina and ipsilateral renal agenesis: review of unusual presentation. J Obstet Gynaecol 30(4):350–353PubMedCrossRef Takagi H, Matsunami K, Imai A (2010) Uterovaginal duplication with blind hemivagina and ipsilateral renal agenesis: review of unusual presentation. J Obstet Gynaecol 30(4):350–353PubMedCrossRef
6.
Zurück zum Zitat Hur JY, Shin JH, Lee JK, Oh MJ, Saw HS, Park YK, Lee KW (2007) Septate uterus with double cervices, unilaterally obstructed vaginal septum, and ipsilateral renal agenesis: a rare combination of müllerian and wolffian anomalies complicated by severe endometriosis in an adolescent. J Minim Invasive Gynecol 14(1):128–131PubMedCrossRef Hur JY, Shin JH, Lee JK, Oh MJ, Saw HS, Park YK, Lee KW (2007) Septate uterus with double cervices, unilaterally obstructed vaginal septum, and ipsilateral renal agenesis: a rare combination of müllerian and wolffian anomalies complicated by severe endometriosis in an adolescent. J Minim Invasive Gynecol 14(1):128–131PubMedCrossRef
7.
Zurück zum Zitat Kimble RMN, Khoo SK, Baatrz D, Kimble RM (2009) The obstructed hemivagina, ipsilateral renal anomaly, uterus didelphys triad. Aust N Z J Obstet Gynaecol 49:554–557PubMedCrossRef Kimble RMN, Khoo SK, Baatrz D, Kimble RM (2009) The obstructed hemivagina, ipsilateral renal anomaly, uterus didelphys triad. Aust N Z J Obstet Gynaecol 49:554–557PubMedCrossRef
8.
Zurück zum Zitat Tsai EM, Chiang PH, Hsu SC, Su JH, Lee JN (1998) Hysteroscopic resection of vaginal septum in an adolescent virgin with obstructed hemivagina. Hum Reprod 13(6):1500–1501PubMedCrossRef Tsai EM, Chiang PH, Hsu SC, Su JH, Lee JN (1998) Hysteroscopic resection of vaginal septum in an adolescent virgin with obstructed hemivagina. Hum Reprod 13(6):1500–1501PubMedCrossRef
9.
Zurück zum Zitat Rock JA, Jones HWJ (1980) The double uterus associated with an obstructed hemivagina and ipsilateral renal agenesis. Am J Obstet Gynecol 138:339–342PubMed Rock JA, Jones HWJ (1980) The double uterus associated with an obstructed hemivagina and ipsilateral renal agenesis. Am J Obstet Gynecol 138:339–342PubMed
10.
Zurück zum Zitat Morgan MA, Thurnau GR, Smith ML (1987) Uterus didelphys with hematocolpos, ipsilateral renal agenesis and menses. A case report and literature review. J Reprod Med 32:47–58PubMed Morgan MA, Thurnau GR, Smith ML (1987) Uterus didelphys with hematocolpos, ipsilateral renal agenesis and menses. A case report and literature review. J Reprod Med 32:47–58PubMed
11.
Zurück zum Zitat Haddad B, Barranger E, Paniel B (1999) Blind hemivagina: long-term follow-up and reproductive performance in 42 cases. Hum Reprod 14(8):1962–1964PubMedCrossRef Haddad B, Barranger E, Paniel B (1999) Blind hemivagina: long-term follow-up and reproductive performance in 42 cases. Hum Reprod 14(8):1962–1964PubMedCrossRef
12.
Zurück zum Zitat Vercellini P, Daguati R, Somigliana E, Viganò P, Lanzani A, Fedele L (2007) Asymmetric lateral distribution of obstructed hemivagina and renal agenesis in women with uterus didelphys: institutional case series and a systematic literature review. Fertil Steril 87(4):719–724PubMedCrossRef Vercellini P, Daguati R, Somigliana E, Viganò P, Lanzani A, Fedele L (2007) Asymmetric lateral distribution of obstructed hemivagina and renal agenesis in women with uterus didelphys: institutional case series and a systematic literature review. Fertil Steril 87(4):719–724PubMedCrossRef
Metadaten
Titel
Clinical characteristics and treatment of Herlyn–Werner–Wunderlich syndrome
verfasst von
Jinhui Wang
Lan Zhu
Jinghe Lang
Zhufeng Liu
Dawei Sun
Jinhua Leng
Qingbo Fan
Publikationsdatum
01.11.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 5/2014
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-014-3286-5

Weitere Artikel der Ausgabe 5/2014

Archives of Gynecology and Obstetrics 5/2014 Zur Ausgabe

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

26.04.2024 Hirsutismus Nachrichten

Laser- und Lichtbehandlungen können bei Frauen mit polyzystischem Ovarialsyndrom (PCOS) den übermäßigen Haarwuchs verringern und das Wohlbefinden verbessern – bei alleiniger Anwendung oder in Kombination mit Medikamenten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bislang gibt es kein Medikament zur Prävention von Wochenbettdepressionen. Das Injektionsanästhetikum Esketamin könnte womöglich diese Lücke füllen.

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

22.04.2024 DGIM 2024 Kongressbericht

Durch die Häufung nach der COVID-19-Pandemie sind Infektionen mit dem Respiratorischen Synzytial-Virus (RSV) in den Fokus gerückt. Fachgesellschaften empfehlen eine Impfung inzwischen nicht nur für Säuglinge und Kleinkinder.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.