Ausgabe 8/2023
Inhalt (12 Artikel)
Clinical Pharmacokinetics and Pharmacodynamics of the Next Generation Androgen Receptor Inhibitor—Darolutamide
Eva Podgoršek, Niven Mehra, Inge M. van Oort, Diederik M. Somford, Emmy Boerrigter, Nielka P. van Erp
Clinical Pharmacology of Brigatinib: A Next-Generation Anaplastic Lymphoma Kinase Inhibitor
Neeraj Gupta, Michael J. Hanley, Robert J. Griffin, Pingkuan Zhang, Karthik Venkatakrishnan, Vikram Sinha
Population Pharmacokinetics of Total Rabbit Anti-thymocyte Globulin in Non-obese Adult Patients Undergoing Hematopoietic Cell Transplantation for Hematologic Malignancy
Takuto Takahashi, Masahiro Teramoto, Kana Matsumoto, Mutaz M. Jaber, Hiroya Tamaki, Kazuhiro Ikegame, Satoshi Yoshihara, Katsuji Kaida
Pharmacokinetics, Pharmacodynamics and Safety of Janagliflozin in Chinese Type 2 Diabetes Mellitus Patients with Renal Impairment
Hengli Zhao, Zhirui Zhao, Kun He, Nianrong Mi, Kai Lou, Xiaolin Dong, Wenyu Zhang, Jingfang Sun, Xinyu Hu, Shuguang Pang, Hong Cheng, Qing Wen
Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates
Bo-Hao Tang, Jin-Yuan Zhang, Karel Allegaert, Guo-Xiang Hao, Bu-Fan Yao, Stephanie Leroux, Alison H. Thomson, Ze Yu, Fei Gao, Yi Zheng, Yue Zhou, Edmund V. Capparelli, Valerie Biran, Nicolas Simon, Bernd Meibohm, Yoke-Lin Lo, Remedios Marques, Jose-Esteban Peris, Irja Lutsar, Jumpei Saito, Evelyne Jacqz-Aigrain, John van den Anker, Yue-E. Wu, Wei Zhao
A Joint Pharmacokinetic Model for the Simultaneous Description of Plasma and Whole Blood Tacrolimus Concentrations in Kidney and Lung Transplant Recipients
Jeroen V. Koomen, Tim J. Knobbe, Tanja R. Zijp, Daan Kremer, C. Tji Gan, Erik A. M. Verschuuren, Stephan J. L. Bakker, Daan J. Touw, Pieter J. Colin
CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients
Ruben A. G. van Eerden, Nikki S. IJzerman, Milan van Meekeren, Esther Oomen-de Hoop, Niels A. D. Guchelaar, Andrea M. W. Visser, Maja Matic, Ron H. N. van Schaik, Peter de Bruijn, Dirk-Jan A. R. Moes, Pieter A. Jobse, Hans Gelderblom, Alwin D. R. Huitema, Neeltje Steeghs, Ron H. J. Mathijssen, Stijn L. W. Koolen
The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis
Urs Duthaler, Fabio Bachmann, Agustos C. Ozbey, Kenichi Umehara, Neil Parrott, Stephen Fowler, Stephan Krähenbühl
Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs
J. M. Janssen, D. Damoiseaux, J. G. C. van Hasselt, F. C. H. Amant, K. van Calsteren, J. H. Beijnen, A. D. R. Huitema, T. P. C. Dorlo
A Randomized Open-Label Study of Relugolix Alone or Relugolix Combination Therapy in Premenopausal Women
Andrea Lukes, Elizabeth Migoya, Brendan Johnson, Tien-Yi Lee, Yulan Li, Juan Camilo Arjona Ferreira
Comment on: “External Evaluation of Population Pharmacokinetic Models for Precision Dosing: Current State and Knowledge Gaps”
Meng Lv, Shengnan Zhang
Authors’ Reply to Lv et al.: “External Evaluation of Population Pharmacokinetic Models for Precision Dosing: Current State and Knowledge Gaps”
Mehdi El Hassani, Amélie Marsot