Erschienen in:
01.09.2007 | Letter
Comment on: Holt HB, Wild SH, Postle AD et al (2007) Cortisol clearance and associations with insulin sensitivity, body fat and fatty liver in middle-aged men. Diabetologia 50:1024–1032
verfasst von:
M. N. Kerstens, R. P. F. Dullaart
Erschienen in:
Diabetologia
|
Ausgabe 9/2007
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Excerpt
To the Editor: In their interesting study, Holt et al. [
1] studied the metabolism of cortisol and its relationship with insulin sensitivity in a group of middle-aged healthy men, with adjustment for fat content, fat distribution and for the presence of non-alcoholic fatty liver disease. One of their key observations was the demonstration of a significant inverse correlation between cortisol clearance and insulin sensitivity, but several methodological issues may hamper the interpretation of their results. …