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Erschienen in:
22.06.2022 | Original Article
Comparison of Asthma Control among Children 5–18 Years of Age by Asthma Control Test Questionnaire of Global Initiative for Asthma 2017 (GINA-2017) Against Spirometry
Erschienen in: Indian Journal of Pediatrics | Ausgabe 8/2023
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Objective
To compare asthma control by Asthma Control Test (ACT)/Childhood Asthma Control Test (cACT) Questionnaire of Global Initiative for Asthma 2017 (GINA-2017) against spirometry in children, 5–18 y of age, with asthma.
Methods
A prospective observational study was conducted between July 2017 and March 2019 in pulmonology OPD of a tertiary care center. Children with asthma aged 5–18 y, falling under the inclusion criteria had spirometry and cACT/ACT questionnaire before starting inhaled corticosteroids. After 12 wk, symptom control was reassessed by ACT/cACT and spirometry. Chi-square/Fischer exact test and paired t-test/Mann–Whitney U test used for qualitative and quantitative data, respectively.
Results
ACT/cACT pretreatment score was 12.76 (2.521), and at follow-up the score was 23.94 (1.941) (p < 0.001). Control by GINA increased from 2.04% to 91.84% at follow-up (p < 0.001). Significant improvement in forced expiratory volume in first second (FEV1), forced expiratory volume/forced vital capacity (FEV1/FVC), forced expiratory flow between 25 and 75% of FVC (FEF25−75) and peak expiratory flow rate (PEFR) between pretreatment and follow-up seen were −71.86%, 106.84%, 101.82%, and 97.51% vs. 82.2%, 109.55%, 110.38%, and 107.00%, respectively. Positive correlation between ACT/cACT and FEV1 (r = 0.26, p ≤ 0.05), PEFR (r = 0.30, p ≤ 0.05).
Conclusions
There is a good correlation of symptom control between ACT/cACT and spirometry with significant positive correlation for FEV1, PEFR.