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Erschienen in: Archives of Virology 5/2017

07.02.2017 | Annotated Sequence Record

Complete genome sequence of Menghai flavivirus, a novel insect-specific flavivirus from China

verfasst von: Xianglilan Zhang, Xiaofang Guo, Hang Fan, Qiumin Zhao, Shuqing Zuo, Qiang Sun, Guangqian Pei, Shi Cheng, Xiaoping An, Yunfei Wang, Zhiqiang Mi, Yong Huang, Zhiyi Zhang, Yigang Tong, Hongning Zhou, Jiusong Zhang

Erschienen in: Archives of Virology | Ausgabe 5/2017

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Abstract

Menghai flavivirus (MFV) was isolated from Aedes albopictus in Menghai county of Yunnan Province, China, during an arboviruses screening program in August 2010. Whole genome sequencing of MFV was performed using an Ion PGM™ Sequencer. The complete genome of MFV was 10897 nucleotides in length and encoded a polyprotein and fairly interesting flavivirus orf (FIFO). The polyprotein contained three flavivirus structural proteins (C, prM/M and E) and seven nonstructural proteins. Nucleotide BLAST analysis revealed that the MFV genome showed highest similarity to Xishuangbanna Aedes flavivirus, a novel insect-specific flavivirus recently isolated from the same area. These species shared a query cover of 99%, but only 71% identity, while FIFO showed no similarity with any of the published sequences. Genomic and phylogenetic analyses suggested that MFV was a novel species of the genus Flavivirus. Our findings enrich our understanding of the genetics and prevalence of the family Flaviviridae.
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Metadaten
Titel
Complete genome sequence of Menghai flavivirus, a novel insect-specific flavivirus from China
verfasst von
Xianglilan Zhang
Xiaofang Guo
Hang Fan
Qiumin Zhao
Shuqing Zuo
Qiang Sun
Guangqian Pei
Shi Cheng
Xiaoping An
Yunfei Wang
Zhiqiang Mi
Yong Huang
Zhiyi Zhang
Yigang Tong
Hongning Zhou
Jiusong Zhang
Publikationsdatum
07.02.2017
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 5/2017
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-017-3232-5

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