Introduction
Materials and methods
Participants
Measures
Statistical analysis
Results
Mean | SD | Minimum | Maximum | |
---|---|---|---|---|
Age, years | 65.24 | 8.29 | 44 | 82 |
Education, years | 10.90 | 4.67 | 3 | 18 |
nM/nF | 26/16 | - | - | - |
Disease duration, years | 10.16 | 5.64 | 2 | 25 |
UPDRS-III | 14.28 | 7.77 | 3 | 34 |
H&Y | 2.2 | 0.64 | 1.5 | 4 |
LEDD | 646.19 | 354.57 | 150 | 1465 |
MoCA total raw score | 21.02 | 4.27 | 13 | 28 |
Visuospatial abilities | 2.56 | 1.04 | 1 | 4 |
Executive functions | 1.88 | 1.45 | 0 | 4 |
Language | 4.60 | 1.44 | 1 | 6 |
Orientation | 5.88 | 0.44 | 4 | 6 |
Attention | 4.84 | 1.14 | 2 | 6 |
MoCA total adjusted score | 21.91 | 3.14 | 15.5 | 27.6 |
PAS score | 10.70 | 9.5 | 0 | 37 |
BDI-II score | 8.1 | 7.06 | 0 | 27 |
DAS total score | 22.55 | 9.32 | 6 | 56 |
DAS emotional | 7.83 | 4.68 | 0 | 18 |
DAS executive | 5.36 | 4.92 | 0 | 21 |
DAS behavioural/cognitive initiation | 9.36 | 4.69 | 1 | 22 |
PDQ-8 total score | 8.07 | 6.93 | 0 | 26 |
TEPS total score | 68.77 | 14.83 | 36 | 90 |
TEPS anticipatory pleasure | 34.15 | 10.22 | 13 | 49 |
TEPS consummatory pleasure | 36.92 | 7.45 | 23 | 47 |
T0 | T1 | Z | p | Cohen dz | |
---|---|---|---|---|---|
LEDD | 646.19 ± 354.57 | 848.4 ± 432.54 | − 2.63 | 0.008 | 0.731 |
UPDRS-III | 14.28 ± 7.77 | 13.52 ± 7.65 | − 1.24 | 0.213 | 0.345 |
H&Y | 2.2 ± 0.64 | 2.37 ± 0.69 | 0.00 | 1.00 | 0.000 |
PAS score | 10.7 ± 9.5 | 8.10 ± 6.56 | − 1.75 | 0.079 | 0.487 |
BDI-II score | 8.10 ± 7.06 | 8.02 ± 4.47 | − 0.85 | 0.392 | 0.237 |
DAS total score | 22.55 ± 9.32 | 20 ± 8.2 | − 1.68 | 0.093 | 0.466 |
DAS emotional | 7.83 ± 4.68 | 5.64 ± 3.5 | − 2.49 | 0.013 | 0.691 |
DAS executive | 5.36 ± 4.92 | 5.88 ± 4.6 | − 0.64 | 0.520 | 0.178 |
DAS behavioural/cognitive initiation | 9.36 ± 4.69 | 8.64 ± 4.9 | − 0.80 | 0.423 | 0.222 |
PDQ-8 total score | 8.07 ± 6.93 | 6.88 ± 4.66 | − 1.03 | 0.300 | 0.277 |
TEPS total score | 68.77 ± 14.83 | 81.29 ± 6.74 | − 2.23 | 0.025 | 0.621 |
TEPS anticipatory pleasure | 34.15 ± 10.22 | 40.55 ± 4.57 | − 1.22 | 0.221 | 0.340 |
TEPS consummatory pleasure | 36.92 ± 7.45 | 40.76 ± 4.14 | − 1.71 | 0.086 | 0.477 |