Erschienen in:
01.06.2021 | COVID-19 | Brief Report
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Management of COVID-19 pneumonia in a child with NEMO deficiency
verfasst von:
Gulsum Alkan, Hasibe Artac, Sadiye Kubra Tuter Oz, Melike Emiroglu
Erschienen in:
Immunologic Research
|
Ausgabe 4/2021
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Excerpt
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by hypomorphic mutations in encoding the nuclear factor κB (NF-κB) essential modulator (NEMO) protein. This primary immunodeficiency disease is characterized by T and B cell dysfunction, antibody deficiency (hypogammaglobulinemia and hyperimmunoglobulin M), low natural killer cell function, and the impairment of encoding cytokines and chemokines. [
1] Patients with NEMO deficiency, susceptibility to bacterial, viral, atypical mycobacterial, and
Pneumocystis jirovecii infections are well defined. [
2] …