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Immunologic Research

Immunologic Research OnlineFirst articles

30.07.2020 | Original Article

Comparative study between human mesenchymal stem cells and etanercept as immunomodulatory agents in rat model of rheumatoid arthritis

To compare human adipose tissue mesenchymal stem cells (AT-MSCs) and etanercept as immunomodulatory agents for collagen-induced arthritis (CIA). CIA was induced by rats’ immunization with collagen type II (CII) in complete Freund’s adjuvant in …

24.07.2020 | Original Article

Blockade of PD-1 and TIM-3 immune checkpoints fails to restore the function of exhausted CD8+ T cells in early clinical stages of chronic lymphocytic leukemia

Blocking antibodies targeting immune checkpoint molecules achieved invaluable success in tumor therapy and amazing clinical responses in a variety of cancers. Although common treatment protocols have improved overall survival in patients with …

26.11.2019 | Original Article

Combined prime-boost immunization with systemic and mucosal pneumococcal vaccines based on Pneumococcal surface protein A to enhance protection against lethal pneumococcal infections

Limited protective effects of commercially available vaccines necessitate the development of novel pneumococcal vaccines. We recently reported a pneumococcal systemic vaccine containing two proteins, Pneumococcal surface protein A (PspA of family …

23.11.2019 | Original Article

Inflammatory involvement into phototoxic reaction in erythropoietic protoporphyria (EPP) patients

Phototoxic reaction is a known feature of EPP at least in part triggered by the oxidative status, complement system activation, and mast cell response. The aim of this study was to verify some aspects involved in phototoxic reaction during a …

23.11.2019 | Letter to the Editor

Effect of atorvastatin on rheumatoid arthritis–associated autoreactive T cells

Utilizing rheumatoid peptides as previously described [ 2 ], we performed an analysis of autoreactive T cells. To determine T cell activation, we used flow cytometry to measure the expression of activity markers HLA-DR and CD25 on CD4+ and CD8+ T …

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IMMUNOLOGIC RESEARCH represents a unique medium for the presentation, interpretation, and clarification of complex scientific data. Information is presented in the form of interpretive synthesis reviews, original research articles, symposia, editorials, and theoretical essays. The scope of coverage extends to cellular immunology, immunogenetics, molecular and structural immunology, immunoregulation and autoimmunity, immunopathology, tumor immunology, host defense and microbial immunity, including viral immunology, immunohematology, mucosal immunity, complement, transplantation immunology, clinical immunology, neuroimmunology, immunoendocrinology, immunotoxicology, translational immunology, and history of immunology.

Edited to serve as an information resource, as well as a conventional medium for innovative original research reports, the journal introduces a format of interpretive synthesis reviews authored by investigators who discovered many of the findings they report.

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