Background
Methods
Study population
Number | 1-, 2-, or 3-Vessel disease | Culprit lesion | Peak CK [U/l] | Peak Troponine T [ng/l] | LV-EF [%] | LV-EDV-I [ml/cm] | LV-M-I [g/cm] |
---|---|---|---|---|---|---|---|
1 | 2 | RD | 1026 | 1656 | 69 | 0.8 | 0.8 |
2 | 3 | LAD | 149 | 1122 | 30 | 1.0 | 0.9 |
3 | 1 | LAD | 1696 | 1280 | 68 | 1.0 | 0.9 |
4 | 1 | LAD | 46 | 834 | 38 | 1.2 | 0.9 |
5 | 2 | RM | 4102 | 9017 | 58 | 1.1 | 0.9 |
6 | 1 | RCA | 3658 | 3239 | 54 | 1.0 | 0.6 |
7 | 1 | RCA | 1900 | 3749 | 51 | 1.3 | 1.3 |
8 | 1 | RCA | 3020 | 5304 | 45 | 1.0 | 0.8 |
CMR examination
Cine imaging
T2-weighted imaging
T2-mapping
T1-mapping
LGE imaging (LGE)
Image analysis
Phantom experiments
Results
Phantom experiments
Reference T2
| Measured T2
| SNR estimate |
39 | 39 ± 3 | 1412.4 |
58 | 65 ± 9 | 1360.6 |
83 | 77 ± 8 | 2386.9 |
Reference T1
| Measured T1
| SNR estimate |
286 | 250 ± 14 | 571.4 |
520 | 473 ± 10 | 649.8 |
630 | 590 ± 14 | 478.9 |
925 | 880 ± 41 | 1106.5 |
1090 | 1062 ± 9 | 1370.5 |
In-vivo-measurements
# | Map | Time | Sg. 1 | Sg. 2 | Sg. 3 | Sg. 4 | Sg. 5 | Sg. 6 | Sg. 7 | Sg. 8 | Sg. 9 | Sg. 10 | Sg. 11 | Sg. 12 | Sg. 13 | Sg. 14 | Sg. 15 | Sg. 16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | T2
| AMI |
58.5
| 49.9 | 46.4 | 49.4 | 45.5 | 43.2 |
69.1
| 47.4 | 47.0 | 47.3 | 44.8 | 52.9 | 46.0 | 47.7 | 50.5 | 60.9 |
CMI |
48.7
| 47.9 | 49.7 | 46.8 | 46.0 | 46.0 |
53.4
| 49.7 | 49.7 | 50.1 | 49.6 | 48.1 | 48.2 | 51.8 | 50.1 | 46.3 | ||
Native T1
| AMI |
1353.5
| 1216.2 | 1168.3 | 1188.4 | 1090.2 | 1111.0 |
1393.9
| 1205.9 | 1177.5 | 1137.8 | 1127.8 | 1282.2 | - | - | - | - | |
CMI |
1387.8
| 1223.3 | 1182.1 | 1181.1 | 1181.2 | 1106.7 |
1412.7
| 1180.3 | 1162.7 | 1074.9 | 1115.9 | 1274.3 | 1243.1 | 1247.6 | 1166.0 | 1232.4 | ||
Post-cm T1
| AMI |
290.8
| 368.7 | 419.0 | 406.1 | 414.1 | 414.4 |
231.2
| 364.8 | 404.5 | 404.4 | 413.4 | 413.4 | 318.8 | 364.6 | 398.7 | 382.0 | |
CMI |
430.4
| 359.8 | 414.1 | 416.1 | 414.1 | 437.8 |
236.3
| 369.8 | 366.1 | 444.7 | 391.1 | 326.5 | 346.9 | 366.9 | 416.7 | 417.7 | ||
2 | T2
| AMI | 43.9 | 45.0 |
42.4
|
-
| - | 43.0 | 51.0 |
55.3
|
46.4
|
50.6
| 44.9 | 46.9 | 52.3 |
55.3
|
49.5
| 51.3 |
CMI | 51.2 | 42.8 |
66.8
|
63.7
| 50.1 | 48.4 | 48.8 |
47.9
|
55.6
|
55.5
| 42.8 | 43.1 | 46.3 |
50.1
|
49.3
| 44.3 | ||
Native T1
| AMI | 1122.0 | 1134.3 |
1280.7
|
-
| - | 1076.3 | 1214.8 |
1288.5
|
1200.6
|
1056.6
| 1075.7 | 1158.8 | 1253.1 |
1327.7
|
1246.3
| 1140.8 | |
CMI | 1059.3 | 1156.2 |
1383.4
|
1364.8
| 1235.9 | 1069.6 | 1059.7 |
1156.2
|
1383.4
|
1364.8
| 1235.9 | 1069.9 | 1196.9 |
1239.7
|
1146.4
| 1155.8 | ||
Post-cm T1
| AMI | 423.6 | 415.0 |
341.6
|
374.7
| 280.4 | 431.8 | 360.2 |
341.0
|
378.4
|
251.0
| 423.7 | 398.5 | 351.9 |
346.9
|
376.7
| 406.5 | |
CMI | 416.2 | 403.9 |
285.3
|
289.4
| 324.6 | 426.4 | 328.4 |
337.4
|
382.7
|
306.1
| 451.3 | 429.0 | 379.7 |
365.9
|
442.9
| 436.9 | ||
3 | T2
| AMI |
51.1
|
44.4
| 44.9 | 45.2 | 44.6 | 43.3 |
52.8
|
45.2
| 43.8 | 42.4 | 40.3 | 43.7 |
57.4
|
62.7
| 45.9 | 43.9 |
CMI |
49.9
|
42.1
| 44.1 | 43.9 | 44.1 | 44.2 |
49.9
|
43.2
| 43.1 | 42.1 | 42.6 | 41.1 |
45.7
|
48.4
| 43.7 | 44.3 | ||
Native T1
| AMI |
1244.2
|
1144.2
| 1135.5 | 1176.8 | 1119.9 | 1129.3 |
1217.4
|
1185.6
| 1174.8 | 1168.0 | 1139.0 | 1170.7 |
1239.0
|
1444.0
| 1213.3 | 1212.6 | |
CMI |
1160.0
|
1134.0
| 1117.8 | - | - | - |
1300.0
|
1141.5
| 1152.0 | 1216.5 | 1123.4 | 1184.6 |
1253.0
|
1250.6
| 1204.9 | 1182.8 | ||
Post-cm T1
| AMI |
409.6
|
468.6
| 471.8 | 475.7 | 458.6 | 458.4 |
413.7
|
383,0
| 441.7 | 492.3 | 463.4 | 462.9 |
411.2
|
333.7
| 467.2 | 460.3 | |
CMI |
403.9
|
421.8
| 419.1 | 440.8 | - | 429.4 |
362.4
|
422.0
| 445.2 | 438.4 | 450.5 | 433.0 |
348.0
|
349.4
| 436.8 | 416.9 | ||
4 | T2
| AMI |
56.5
|
58.0
|
51.8
| 50.5 | 49.6 | 46.5 |
-
|
62.4
|
58.7
| 53.5 | 49.6 | 53.5 |
61.5
|
57.0
| 56.9 | 60.2 |
CMI |
51.7
|
56.9
|
61.4
| 53.5 | 54.1 | 49.5 |
57.0
|
53.8
|
54.8
| 53.8 | 51.1 | 54.7 |
53.7
|
52.7
| 54.3 | 51.6 | ||
Native T1
| AMI |
1326.1
|
1344.8
|
1271.8
| 1184.9 | 1272.8 | 1246.7 |
1370.8
|
1334.8
|
1327.6
| 1193.3 | - | 1215.9 |
1388.5
|
1473.2
| 1304.5 | 1155.1 | |
CMI |
1171.9
|
1230.0
|
1364.6
| 1284.5 | 1249.3 | 1102.7 |
1224.9
|
1269.1
|
1278.4
| 1199.9 | 1186.8 | 1233.2 |
1236.9
|
1278.9
| 1241.6 | 1184.5 | ||
Post-cm T1
| AMI |
-
|
337.5
|
383.8
| 394.0 | 444.4 | 418.4 |
-
|
327.0
|
394.9
| 423.5 | 417.7 | 379.6 |
329.3
|
315.9
| 390.6 | 412.3 | |
CMI |
-
|
310.1
|
362.3
| 461.1 | 456.9 | 421.5 |
369.3
|
310.1
|
362.3
| 451.3 | 455.5 | 421.5 |
372.8
|
322.7
| 430.1 | 411.9 | ||
5 | T2
| AMI | 45.7 | 45.0 | 51.5 | 51.2 |
56.7
|
55.2
| 48.2 | 44.5 | 50.3 | 48.9 |
58.1
|
53.5
| 52.7 | 47.0 | 47.2 | 57.2 |
CMI | 45.0 | 44.4 | 48.0 | 47.7 |
47.7
|
48.4
| 55.5 | 43.2 | 43.1 | 52.9 |
47.0
|
48.5
| 47.2 | 50.2 | 48.6 | 44.6 | ||
Native T1
| AMI | 1124.3 | 1206.7 | 1195.1 | 1207.0 |
1205.9
|
1128.9
| 1060.3 | 1138.6 | 1169.2 | 1179.3 |
1199.7
|
1158.1
| 1098.9 | 1168.6 | 1201.4 | 1305.3 | |
CMI | - | - | 1202.1 | 1190.3 |
1225.7
|
1211.2
| 1138.6 | 1139.2 | 1175.5 | 1368.9 |
1276.1
|
1205.1
| 1148.9 | 1148.8 | - | 1212.1 | ||
Post-cm T1
| AMI | 484.1 | 464.7 | 465.3 | 482.4 |
391.8
|
387.0
| 473.4 | 489.3 | 485.8 | 497.0 |
405.2
|
395.4
| 436.8 | 456.8 | 513.0 | 415.3 | |
CMI | 326.9 | 332.1 | 332.8 | 333.4 |
275.9
|
228.8
| 489.3 | 456.3 | 468.8 | 483.1 |
379.7
|
330.0
| 441.7 | 449.7 | 490.0 | 448.7 | ||
6 | T2
| AMI | 46.3 | 45.2 | 47.5 | 52.4 |
56.5
|
54.5
| 48.2 | 46.6 | 47.1 | 51.0 |
59.5
|
50.4
| 44.6 | 48.4 | 64.7 |
55.8
|
CMI | 46.5 | 46.2 | 49.5 | 49.2 |
57.7
|
51.1
| 48.1 | 44.0 | 48.8 | 53.1 |
56.8
|
48.7
| 48.1 | 53.1 | 56.8 |
48.7
| ||
Native T1
| AMI | 1169.3 | 1242.5 | 1228.4 | - |
1406.4
|
1376.2
| 1224.6 | 1230.6 | 1257.8 | 1269.2 |
1350.0
|
1379.3
| 1160.4 | 1200.0 | 1413.6 |
1359.2
| |
CMI | 1356.9 | 1247.2 | 1219.7 | 1205.7 |
1332.1
|
1430.5
| - | - | - | - |
-
|
-
| 1146.1 | 1178.7 | 1264.5 |
1300.7
| ||
Post-cm T1
| AMI | 474.0 | 474.0 | 474.2 | 447.9 |
334.9
|
356.7
| 485.1 | 432.3 | 465.8 | 370.5 |
346.1
|
477.9
| 480.0 | 471.8 | 392.2 |
428.8
| |
CMI | 334.3 | 370.5 | 360.7 | 359.0 |
303.6
|
246.7
| 327.2 | 383.7 | 395.6 | 294.1 |
303.1
|
379.2
| 402.2 | 406.4 | 380.5 |
276.5
| ||
7 | T2
| AMI | 51.7 | 55.4 |
73.7
|
77.3
| 55.3 | 54.5 | 51.1 | 57.2 |
76.6
|
79.9
| 52.0 | 52.6 | - | - | - | - |
CMI | 48.2 | 49.0 |
48.5
|
56.8
| - | 46.7 | 51.1 | 51.6 |
61.9
|
55.4
| 50.6 | 49.7 | 48.1 | 50.9 | 56.3 | 45.4 | ||
Native T1
| AMI | 1202.6 | 1333.5 |
1423.4
|
1539.3
| 1328.1 | 1216.3 | 1120.2 | 1246.5 |
1522.5
|
1474.8
| 1214.9 | 1186.9 | - | - | - | - | |
CMI | 1183.5 | 1234.8 |
1326.9
|
1395.0
| 1216.2 | 1248.2 | 1158.1 | 1245.3 |
1334.1
|
1298.4
| - | 1207.3 | 1198.3 | 1254.1 | 1354.8 | - | ||
Post-cm T1
| AMI | 517.1 | 484.0 |
329.7
|
289.8
| 463.3 | 511.3 | 527.3 | 485.6 |
342.3
|
399.0
| 523.1 | 518.8 | - | - | - | - | |
CMI | 480.0 | 463.6 |
342.0
|
280.8
| 436.7 | 471.2 | 492.0 | 462.0 |
426.9
|
336.1
| - | 485.7 | 491.9 | 461.9 | 332.9 | 483.2 | ||
8 | T2
| AMI | 51.2 | 53.4 | 63.8 |
58.3
|
57.1
| 51.8 | 53.0 | 51.5 | 66.9 |
63.9
|
58.8
| 54.7 | 55.1 | 54.5 |
62.4
| 57.6 |
CMI | 50.3 | 53.6 | 56.0 |
54.7
|
46.4
| 49.3 | 47.8 | 49.4 | 59.1 |
61.8
|
50.8
| 47.8 | 48.9 | 50.3 |
59.1
| 48.6 | ||
Native T1
| AMI | 1182.4 | 1196.6 | 1338.9 |
1402.0
|
1329.1
| 1194.3 | 1157.9 | 1216.7 | 1396.3 |
1383.0
|
1268.0
| 1224.3 | 1207.2 | 1279.9 |
1500.1
| 1296.4 | |
CMI | 1247.9 | 1236.2 | 1299.9 |
1291.7
|
1229.7
| 1228.7 | 1184.6 | 1190.6 | 1311.3 |
1350.4
|
1253.1
| 1246.0 | 1215.2 | 1241.6 |
1346.4
| 1316.8 | ||
Post-cm T1
| AMI | 465.5 | 441.5 | 374.6 |
331.4
|
386.7
| 457.2 | 434.6 | 423.8 | 367.5 |
314.7
|
411.0
| 435.6 | 424.4 | 414.8 |
331.5
| 429.8 | |
CMI | 492.2 | 503.4 | 505.4 |
350.5
|
386.5
| 525.4 | 512.3 | 547.9 | 515.5 |
385.6
|
551.5
| 558.6 | 509.3 | 547.7 |
480.2
| 541.0 |