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Erschienen in: Der Urologe 4/2006

01.09.2006 | Leitthema

Das Nierenzellkarzinom

verfasst von: PD Dr. A. Haferkamp, D. Rohde, S. C. Müller, H. Rübben, M. Hohenfellner

Erschienen in: Die Urologie | Sonderheft 4/2006

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Zusammenfassung

Seit seiner Entdeckung vor 165 Jahren haben sich sowohl in der Diagnostik als auch in der Therapie des Nierenzellkarzinoms große Fortschritte bemerkbar gemacht. Während zunächst eine Standardisierung der Operationstechnik zu einer deutlich verbesserten Langzeitprognose der Patienten führte, sorgte die Einführung von Sonographie, Computertomographie (CT) und Magnetresonanztomographie (MRT) dafür, dass vermehrt kleine inzidentelle Karzinome detektiert wurden, was wiederum in einer besseren Prognose resultierte. Neuere Operationstechniken wie die organerhaltende Tumorresektion oder minimal-invasive Verfahren führten zu weiteren Verbesserungen der operativen Therapie. Beim metastasierten Nierenzellkarzinom stellt die Immuntherapie mit Zytokinen eine wichtige Säule zur Behandlung der Patienten dar. Neue Substanzen, die Faktoren für Tumorzellwachstum und Angiogenese inhibieren, eröffnen neue Therapieansätze, die sich in den nächsten Jahren verstärkt durchsetzen werden.
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Metadaten
Titel
Das Nierenzellkarzinom
verfasst von
PD Dr. A. Haferkamp
D. Rohde
S. C. Müller
H. Rübben
M. Hohenfellner
Publikationsdatum
01.09.2006
Verlag
Springer-Verlag
Erschienen in
Die Urologie / Ausgabe Sonderheft 4/2006
Print ISSN: 2731-7064
Elektronische ISSN: 2731-7072
DOI
https://doi.org/10.1007/s00120-006-1136-1

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