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Erschienen in: Heart and Vessels 1/2022

10.08.2021 | Original Article

Decrease in red cell distribution width as a useful predictor of success after catheter ablation for atrial fibrillation: a retrospective multi-center study

verfasst von: Issei Yoshimoto, Koichi Inoue, Naoya Oketani, Hitoshi Ichiki, Masato Okada, Nobuaki Tanaka, Yuko Hirao, Takafumi Oka, Koji Tanaka, Shinichi Harada, Toshinari Onishi, Yasushi Koyama, Atsunori Okamura, Katsuomi Iwakura, Kenshi Fujii, Masaaki Miyata, Mitsuru Ohishi

Erschienen in: Heart and Vessels | Ausgabe 1/2022

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Abstract

Red cell distribution width (RDW) is reportedly associated with cardiovascular events, including atrial fibrillation (AF). We investigated whether the RDW values were associated with the outcomes of catheter ablation for AF. This retrospective multicenter study included 501 patients with AF (239 paroxysmal AF cases, 196 persistent AF cases, and 66 long-standing persistent AF cases) who underwent initial AF ablation between March 2017 and May 2018. The RDW values were evaluated before and at 1–3 months after the procedure. The patients were stratified based on the recurrence of AF within 1 year after the index procedure with a blanking period of 3 months into recurrence group (107 patients, 21.4%) and no-recurrence group (394 patients, 78.6%). There were no significant differences in preoperative RDW values between the groups (p = 0.37). The RDW value did not change significantly after the ablation in the recurrence group (13.55–13.60%, p = 0.37), although it decreased significantly in the no-recurrence group (13.64–13.37%, p < 0.001). Multivariate Cox proportional hazards regression analyses revealed that a postoperative change in RDW (ΔRDW) was independently associated with AF recurrence (hazard ratio 2.00, 95% confidence interval 1.42–2.76, p < 0.001). Receiver operating characteristic curve analysis revealed that a ΔRDW cut-off value of − 0.1% provided a c-statistic of 0.65 for predicting AF recurrence. Decrease in RDW during the blanking period after ablation independently predicted the 1-year success of AF ablation.
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Metadaten
Titel
Decrease in red cell distribution width as a useful predictor of success after catheter ablation for atrial fibrillation: a retrospective multi-center study
verfasst von
Issei Yoshimoto
Koichi Inoue
Naoya Oketani
Hitoshi Ichiki
Masato Okada
Nobuaki Tanaka
Yuko Hirao
Takafumi Oka
Koji Tanaka
Shinichi Harada
Toshinari Onishi
Yasushi Koyama
Atsunori Okamura
Katsuomi Iwakura
Kenshi Fujii
Masaaki Miyata
Mitsuru Ohishi
Publikationsdatum
10.08.2021
Verlag
Springer Japan
Erschienen in
Heart and Vessels / Ausgabe 1/2022
Print ISSN: 0910-8327
Elektronische ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-021-01891-2

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