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Erschienen in: Digestive Diseases and Sciences 6/2007

01.06.2007 | Review article

Detection and Treatment of Early Flat and Depressed Colorectal Cancer Using High-Magnification Chromoscopic Colonoscopy: A Change in Paradigm for Western Endoscopists?

verfasst von: David Paul Hurlstone, David S. Sanders, Mike Thomson

Erschienen in: Digestive Diseases and Sciences | Ausgabe 6/2007

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Abstract

Japanese researchers reported flat and depressed colorectal lesions in the 1980s. Such lesions were thought irrelevant to Western populations and described as “Phantom” or “Akitas” carcinoma. Many depressed neoplasms arise through the de novo pathogenic sequence and demonstrate early invasive characteristics. All investigators report difficulties in identifying flat and depressed lesions using conventional colonoscopy. Failure to detect and treat such lesions may be responsible for the current shortfalls in secondary colorectal cancer prevention. Given the introduction of colorectal cancer screening programs in the United Kingdom, Europe, and the United States, it is essential to re-evaluate the significance of flat lesions as applicable to Western cohorts and explore the safety and efficacy of new endoscopic technology and interventional therapeutics.
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Metadaten
Titel
Detection and Treatment of Early Flat and Depressed Colorectal Cancer Using High-Magnification Chromoscopic Colonoscopy: A Change in Paradigm for Western Endoscopists?
verfasst von
David Paul Hurlstone
David S. Sanders
Mike Thomson
Publikationsdatum
01.06.2007
Erschienen in
Digestive Diseases and Sciences / Ausgabe 6/2007
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-006-9460-2

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