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Japanese Journal of Radiology
Erschienen in: Japanese Journal of Radiology 3/2014

01.03.2014 | Original Article

Detection of skeletal muscle metastases on initial staging of lung cancer: a retrospective case series

verfasst von: Marialuisa Bocchino, Tullio Valente, Francesco Somma, Ilaria de Rosa, Marco Bifulco, Gaetano Rea

Erschienen in: Japanese Journal of Radiology | Ausgabe 3/2014

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Abstract

Purpose

Estimation of skeletal muscle metastases (SMMs) at the time of diagnosis and/or initial staging of lung cancer.

Materials and methods

Retrospective evaluation of clinical charts and imaging data suggestive of SMMs of patients with histology-proved lung cancer over a 5-year period.

Results

SMMs were identified in 46 out of 1,754 patients. Single and multiple (62.9 % of cases) SMMs were detected by total body multi-detector computed tomography (MDCT). They were associated with poorly differentiated (43 %) and advanced adenocarcinomas (52 %) without clinically relevant symptoms and/or signs. Psoas and buttock muscles were most frequently involved (33.3 %). MDCT findings consisted of well-defined homogeneously hyperdense oval masses (31 %), lesions with ring-like enhancement and central hypoattenuation (68 %), or large abscess-like necrotic lesions (24 %). Sonography revealed well-defined hypoechoic masses (41.6 %), ill-defined hypoechoic lesions (33.3 %), or anechoic areas with a necrotic centre (25 %). Positron emission tomography revealed that all SMMs were metabolically active.

Conclusions

SMMs are uncommon but not negligible in lung cancer, with an estimated prevalence of 2.62 % in our series. Although histology remains the recommended method, use of high-performance imaging techniques and increased clinical suspicion may improve their early detection. Efforts addressing their effect on the natural history of lung cancer are needed.
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Metadaten
Titel
Detection of skeletal muscle metastases on initial staging of lung cancer: a retrospective case series
verfasst von
Marialuisa Bocchino
Tullio Valente
Francesco Somma
Ilaria de Rosa
Marco Bifulco
Gaetano Rea
Publikationsdatum
01.03.2014
Verlag
Springer Japan
Erschienen in
Japanese Journal of Radiology / Ausgabe 3/2014
Print ISSN: 1867-1071
Elektronische ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-014-0281-5

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