Background
Methods
Study design
Study site
Case selection
Case
Control
Inclusion criteria
Exclusion criteria
Sample size calculation
Data collection technique and tools
Data processing and analysis
Ethical consideration
Results
Socio demographic characteristics of study participants
Variable | No. of Cases (%) (n = 120) | No. of Control (%) (n = 240) |
---|---|---|
Age group of mother (years) | ||
19 and below | 10 (8.3) | 18 (7.5) |
20–29 | 51 (42.5) | 103 (42.9) |
30+ | 59 (49.2) | 119 (49.6) |
Marital status of mother | ||
Married | 83 (69.2) | 186 (78.5) |
Not married | 37 (30.8) | 51 (21.5) |
Mothers occupation | ||
Farming | 17 (14.3) | 28 (11.8) |
Trader/artisan | 63 (52.9) | 136 (57.1) |
Government/formal job | 16 (13.4) | 33 (13.9) |
Unemployed | 23 (19.3) | 41 (17.2) |
Residence of mother | ||
Urban | 69 (61.1) | 172 (73.5) |
Rural | 44 (38.9) | 62 (26.5) |
Anthropometric characteristics of study participants
Variables | Cases(N = 120) N (%) | Controls (N = 240) N (%) | OR | 95% CI | p-value |
---|---|---|---|---|---|
Mothers height(m) | |||||
1.46 m or above (normal) | 103 (97.2) | 221 (97.8) | 1 | ref | |
Below 1.46 m(short) | 3 (2.8) | 5 (2.2) | 1.29 | 0.20–6.75 | 0.50 ˄ |
Mothers weight | |||||
45 kg and above | 107 (97.3) | 219 (96.5) | 1 | ref | |
Below 45 kg | 3 (2.7) | 8 (3.5) | 0.77 | 0.13–3.27 | 0.50 ˄ |
BMI of mother (kg/m2) | |||||
18.5–24.9 (normal) | 58 (56.9) | 138 (63.3) | 1 | ref | |
Below 18.5 (underweight) | 3 (2.9) | 13 (6.0) | 0.55 | 0.15–2.01 | 0.36 |
Above 24.9(obese) | 41 (40.2) | 67 (30.7) | 1.46 | 0.89–2.40 | 0.14 |
Obstetric characteristics of study participants
Variables | Cases (N = 120) N (%) | Controls (N = 240) N (%) | OR | 95% CI | P-value |
---|---|---|---|---|---|
Gestation at booking | |||||
1st trimester | 68 (64.8) | 161 (69.1) | 1 | ref | |
2nd trimester | 26 (24.8) | 67 (28.8) | 0.92 | 0.54–1.57 | 0.76 |
3rd trimester | 11 (10.5) | 5 (2.1) | 5.21 | 1.70–15.98 | < 0.001 |
ANC visits | |||||
4 and above | 97 (82.2) | 228 (95.8) | 1 | Ref | |
0–3 | 21 (17.8) | 10 (4.2) | 4.94 | 2.12–11.12 | < 0.001 |
Planned pregnancy | |||||
Yes | 64 (53.8) | 155 (65.1) | 1 | ref | |
No | 55 (46.2) | 83 (34.9) | 1.6 | 1.00–2.53 | 0.038 |
Mode of delivery | |||||
Spontaneous | 73 (61.3) | 172 (72.3) | 1 | Ref | |
Caesarian section | 46 (38.7) | 66 (27.7) | 1.64 | 1.00–2.68 | 0.036 |
Parity | |||||
Nulliparity | 44 (37.3) | 62 (26.1) | 2.66 | 1.09–6.48 | 0.024 |
Primiparity | 21 (17.80 | 55 (23.1) | 1.43 | 0.56–3.65 | 0.45 |
Multiparty(2–3) | 45 (38.1) | 91 (38.2) | 1.85 | 0.78–4.41 | 0.16 |
Grand multiparity(4+) | 8 (6.8) | 30 (12.6) | 1 | ref | |
Family planning method | |||||
No | 84 (70.0) | 185 (77.1) | 1 | Ref | |
Yes | 36 (30.0) | 55 (22.9) | 1.45 | 0.86–2.44 | 0.14 |
Previous abortion | |||||
No | 96 (80.0) | 192 (80.0) | 1 | ref | |
Yes | 24 (20.0) | 48 (20.0) | 1.01 | 0.55–1.79 | 0.99 |
Previous LBW/premature Delivery | |||||
No | 109 (90.8) | 232 (96.3) | 1 | ref | |
Yes | 11 (9.2) | 9 (3.7) | 2.6 | 0.95–7.31 | 0.034 |
Maternal health characteristics of study participants
Variables | Cases(N = 120) N (%) | Controls(N = 240) N (%) | OR | 95% CI | p-value |
---|---|---|---|---|---|
First trimester hemoglobin | |||||
11 g/dl and above | 39 (33.3) | 124 (52.1) | 1 | ref | |
Below 11 g/dl | 78 (66.6) | 114 (47.9) | 2.18 | 1.34–3.55 | < 0.001 |
Hospital admissions in pregnancy | |||||
No | 72 (60.0) | 191 (79.9) | 1 | ref | |
Yes | 48 (40) | 48 (20.1) | 2.65 | 1.59–4.42 | < 0.001 |
Iron supplementation intake | |||||
Always | 69 (57.5) | 175 (73.2) | 1 | ref | |
Not regularly | 32 (26.7) | 47 (19.7) | 1.73 | 1.01–2.94 | 0.042 |
Never | 19 (15.8) | 17 (7.1) | 2.83 | 1.37–5.85 | < 0.001 |
Poor appetite | |||||
No | 49 (41.2) | 122 (52.6) | 1 | ref | |
Yes | 70 (58.8) | 110 (47.4) | 1.58 | 0.99–2.54 | 0.043 |
Poor appetite | |||||
No | 49 (41.2) | 122 (52.6) | 1 | ref | |
Yes | 70 (58.8) | 110 (47.4) | 1.58 | 0.99–2.54 | 0.043 |
Intake of Herbal medications | |||||
No | 92 (76.7) | 218 (90.8) | 1 | ref | |
Yes | 28 (23.3) | 22 (9.2) | 3.02 | 1.57–5.84 | < 0.001 |
Determinants of LBW among study participants
Characteristics | Cases N = 120 (%) | Controls N = 240 (%) | cOR (95%CI) | aOR (95%C) |
---|---|---|---|---|
Gestation at delivery | ||||
Term delivery(37–40 weeks) | 76 (63.3) | 228 (95.8) | 1 | 1 |
Preterm delivery(32-36 weeks) | 32 (26.4) | 9 (3.8) | 10.5* (4.46–24.68) | 13.70* (4.64–40.45) |
Severe preterm delivery (< 32 weeks) | 12 (10.3) | 1 (0.4) | 61.89* (6.84–560.33) | 58.50* (6.66–513.87) |
Educational level of mother | ||||
Post-secondary/tertiary | 16 (13.4) | 43 (18.1) | 1 | 1 |
Primary/JHS | 35 (29.4) | 101 (42.0) | 0.94 (0.47–1.88) | 1.15 (0.39–3.40) |
Secondary | 57 (47.1) | 68 (28.2) | 2.25* (1.13–4.47) | 4.19* (1.45–12.07) |
No formal education | 12 (10.1) | 28 (11.8) | 1.16 (0.47–2.81) | 1.88 (0.46–7.63) |
Supplementary iron intake | ||||
Regular intake | 69 (57.5) | 175 (73.2) | 1 | 1 |
Irregular intake | 32 (26.7) | 47 (19.7) | 1.73* (1.01–2.94) | 2.19 (0.99–4.84) |
No intake | 19 (15.8) | 17 (7.1) | 2.83* (1.37–5.85) | 3.19* (0.99–4.84) |
Who mother lived with during pregnancy | ||||
Partner | 55 (46.2) | 157 (65.4) | 1 | 1 |
Extended family | 41 (34.5) | 63 (26.2) | 1.86* (1.12–3.09) | 2.43* (1.15–5.10) |
Lived alone | 23 (19.3) | 20 (8.4) | 3.24* (1.62–6.48) | 3.95* (1.33–11.74) |
1st trimester hemoglobin | ||||
11 g/dl and above | 39 (33.3) | 125 (52.1) | 1 | 1 |
Below 11 g/dl | 78 (66.6) | 115 (47.9) | 2.18* (1.34–3.55) | 3.14* (1.50–6.58) |
Hospital admissions during pregnancy | ||||
No | 72 (60.0) | 192 (79.9) | 1 | 1 |
Yes | 48 (40) | 48 (20.1) | 2.65* (1.59–4.42) | 2.08 (1.00–4.30) |