Diabetologia

Up Front

Referees 2020

Celebrating 100 years of insulin

Sally M. Marshall

The discovery of insulin in Toronto: beginning a 100 year journey of research and clinical achievement

Michael Fralick, Bernard Zinman

A global perspective on the issue of access to insulin

David Beran, Maria Lazo-Porras, Camille M. Mba, Jean Claude Mbanya

The consequences of hypoglycaemia

Stephanie A. Amiel

Consequences of recurrent hypoglycaemia on brain function in diabetes

Rory J. McCrimmon

Minimising hypoglycaemia in the real world: the challenge of insulin

Chantal Mathieu

Hypothalamic glucose-sensing mechanisms

Nal Ae Yoon, Sabrina Diano

Defining the underlying defect in insulin action in type 2 diabetes

Thiago M. Batista, Nida Haider, C. Ronald Kahn

New closed-loop insulin systems

Charlotte K. Boughton, Roman Hovorka

‘Smart’ insulin-delivery technologies and intrinsic glucose-responsive insulin analogues

Mark A. Jarosinski, Balamurugan Dhayalan, Nischay Rege, Deepak Chatterjee, Michael A. Weiss

The promise of stem cell-derived islet replacement therapy

Douglas Melton

Current and future therapies for type 1 diabetes

Bernt Johan von Scholten, Frederik F. Kreiner, Stephen C. L. Gough, Matthias von Herrath

Realising the long-term promise of insulin therapy: the DCCT/EDIC study

David M. Nathan

Transforming type 1 diabetes: the next wave of innovation

Daniel J. Drucker

Efficacy and safety of PEGylated exenatide injection (PB-119) in treatment-naive type 2 diabetes mellitus patients: a Phase II randomised, double-blind, parallel, placebo-controlled study

Linong Ji, Ying Du, Min Xu, Xiangjun Zhou, Zhaohui Mo, Jianhua Ma, Jiarui Li, Yufeng Li, Jingna Lin, Yanjun Wang, Jing Yang, Weihong Song, Hui Jin, Shuguang Pang, Hui Liu, Ping Li, Jie Liu, Minxiu Yao, Wenhui Li, Xiaohong Jiang, Feixia Shen, Houfa Geng, Haifeng Zhou, Jianmin Ran, Minxiang Lei, Yinghong Du, Shandong Ye, Qingbo Guan, Wenshan Lv, Huiwen Tan, Tao Chen, Jinkui Yang, Guijun Qin, Shiyun Li, Lei Chen

Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial

Robin Assfalg, Jan Knoop, Kristi L. Hoffman, Markus Pfirrmann, Jose Maria Zapardiel-Gonzalo, Anna Hofelich, Anne Eugster, Marc Weigelt, Claudia Matzke, Julia Reinhardt, Yannick Fuchs, Melanie Bunk, Andreas Weiss, Markus Hippich, Kathrin Halfter, Stefanie M. Hauck, Jörg Hasford, Joseph F. Petrosino, Peter Achenbach, Ezio Bonifacio, Anette-Gabriele Ziegler

Potential diabetes overtreatment and risk of adverse events among older adults in Ontario: a population-based study

Iliana C. Lega, Michael A. Campitelli, Peter C. Austin, Yingbo Na, Afshan Zahedi, Freda Leung, Catherine Yu, Susan E. Bronskill, Paula A. Rochon, Lorraine L. Lipscombe

Retinal venular tortuosity and fractal dimension predict incident retinopathy in adults with type 2 diabetes: the Edinburgh Type 2 Diabetes Study

Rachel B. Forster, Emmanuel Sandoval Garcia, Anniek J. Sluiman, Sheila M. Grecian, Stela McLachlan, Tom J. MacGillivray, Mark W. J. Strachan, Jackie F. Price

Size for gestational age affects the risk for type 1 diabetes in children and adolescents: a Swedish national case–control study

Nina Lindell, Marie Bladh, Annelie Carlsson, Ann Josefsson, Karin Aakesson, Ulf Samuelsson

Association of infant diet with subsequent obesity at 2–5 years among children exposed to gestational diabetes: the SWIFT study

Sarvenaz Vandyousefi, Jaimie N. Davis, Erica P. Gunderson

Biphasic dynamics of beta cell mass in a mouse model of congenital hyperinsulinism: implications for type 2 diabetes

Sharona Tornovsky-Babeay, Noa Weinberg-Corem, Rachel Ben-Haroush Schyr, Dana Avrahami, Judith Lavi, Eseye Feleke, Klaus H. Kaestner, Yuval Dor, Benjamin Glaser

Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function

Mu Zhang, Chunjie Yang, Meng Zhu, Li Qian, Yan Luo, Huimin Cheng, Rong Geng, Xiaojun Xu, Cheng Qian, Yu Liu

Heterogeneity in insulin-stimulated glucose uptake among different muscle groups in healthy lean people and people with obesity

Han-Chow E. Koh, Stephan van Vliet, Gretchen A. Meyer, Richard Laforest, Robert J. Gropler, Samuel Klein, Bettina Mittendorfer

Genetic ablation of C-reactive protein gene confers resistance to obesity and insulin resistance in rats

Mengliu Yang, Sheng Qiu, Yirui He, Ling Li, Tong Wu, Ning Ding, Fanghong Li, Allan Z. Zhao, Gangyi Yang

The disproportionate excess mortality risk of COVID-19 in younger people with diabetes warrants vaccination prioritisation

Andrew P. McGovern, Nick J. Thomas, Sebastian J. Vollmer, Andrew T. Hattersley, Bilal A. Mateen, John M. Dennis