Diabetologia

Up Front

Quantifying beta cell function in the preclinical stages of type 1 diabetes

Alfonso Galderisi, Alice L. J. Carr, Mariangela Martino, Peter Taylor, Peter Senior, Colin Dayan

The challenges of identifying and studying type 1 diabetes in adults

Nicholas J. Thomas, Angus G. Jones

Clinical impact of an integrated e-health system for diabetes self-management support and shared decision making (POWER2DM): a randomised controlled trial

Merel M. Ruissen, José D. Torres-Peña, Bas S. Uitbeijerse, Antonio P. Arenas de Larriva, Sasja D. Huisman, Tuncay Namli, Eckhard Salzsieder, Lutz Vogt, Manuela Ploessnig, Bob van der Putte, Armelle Merle, Gustavo Serra, Gustavo Rodríguez, Albert A. de Graaf, Eelco J. P. de Koning, Javier Delgado-Lista, Jacob K. Sont

Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes

Pernille Svalastoga, Alba Kaci, Janne Molnes, Marie H. Solheim, Bente B. Johansson, Lars Krogvold, Torild Skrivarhaug, Eivind Valen, Stefan Johansson, Anders Molven, Jørn V. Sagen, Eirik Søfteland, Lise Bjørkhaug, Erling Tjora, Ingvild Aukrust, Pål R. Njølstad

Elevated remnant cholesterol and atherosclerotic cardiovascular disease in diabetes: a population-based prospective cohort study

Benjamin N. Wadström, Kasper M. Pedersen, Anders B. Wulff, Børge G. Nordestgaard

Identifying the severity of diabetic retinopathy by visual function measures using both traditional statistical methods and interpretable machine learning: a cross-sectional study

David M. Wright, Usha Chakravarthy, Radha Das, Katie W. Graham, Timos T. Naskas, Jennifer Perais, Frank Kee, Tunde Peto, Ruth E. Hogg

Racial/ethnic and socioeconomic disparities in achievement of treatment goals within a clinical trial: a secondary analysis of the ACCORD trial

Sara J. Cromer, Tanayott Thaweethai, Deborah J. Wexler

Association between timing and consistency of physical activity and type 2 diabetes: a cohort study on participants of the UK Biobank

Caiwei Tian, Charlyne Bürki, Kenneth E. Westerman, Chirag J. Patel

High proinsulin:C-peptide ratio identifies individuals with stage 2 type 1 diabetes at high risk for progression to clinical diagnosis and responses to teplizumab treatment

Emily K. Sims, Susan M. Geyer, S. Alice Long, Kevan C. Herold

CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice

Angela J. T. Bosch, Lena Keller, Laura Steiger, Theresa V. Rohm, Sophia J. Wiedemann, Andy J. Y. Low, Marc Stawiski, Leila Rachid, Julien Roux, Daniel Konrad, Stephan Wueest, Sonia Tugues, Melanie Greter, Marianne Böni-Schnetzler, Daniel T. Meier, Claudia Cavelti-Weder

Contribution of intestinal triglyceride-rich lipoproteins to residual atherosclerotic cardiovascular disease risk in individuals with type 2 diabetes on statin therapy

Marja-Riitta Taskinen, Niina Matikainen, Elias Björnson, Sanni Söderlund, Jussi Inkeri, Antti Hakkarainen, Helka Parviainen, Carina Sihlbom, Annika Thorsell, Linda Andersson, Martin Adiels, Chris J. Packard, Jan Borén

The metabolic response of human trophoblasts derived from term placentas to metformin

Jane L. Tarry-Adkins, India G. Robinson, Lucas C. Pantaleão, Jenna L. Armstrong, Benjamin D. Thackray, Lorenz M. W. Holzner, Alice E. Knapton, Sam Virtue, Benjamin Jenkins, Albert Koulman, Andrew J. Murray, Susan E. Ozanne, Catherine E. Aiken

Structural changes in Schwann cells and nerve fibres in type 1 diabetes: relationship with diabetic polyneuropathy

Xiaoli Hu, Christian Selmer Buhl, Marie Balle Sjogaard, Karoline Schousboe, Hatice Isik Mizrak, Huda Kufaishi, Troels Staehelin Jensen, Christian Stevns Hansen, Knud Bonnet Yderstræde, Ming-Dong Zhang, Patrik Ernfors, Jens Randel Nyengaard, Pall Karlsson

Improved prediction of long-term kidney outcomes in people with type 2 diabetes by levels of circulating haematopoietic stem/progenitor cells

Benedetta Maria Bonora, Mario Luca Morieri, Marella Marassi, Roberta Cappellari, Angelo Avogaro, Gian Paolo Fadini

Continuous glucose monitoring-derived time in range and CV are associated with altered tissue characteristics of the carotid artery wall in people with type 2 diabetes

Tomoya Mita, Naoto Katakami, Yosuke Okada, Hidenori Yoshii, Takeshi Osonoi, Keiko Nishida, Toshihiko Shiraiwa, Akira Kurozumi, Naohiro Taya, Satomi Wakasugi, Fumiya Sato, Ryota Ishii, Masahiko Gosho, Iichiro Shimomura, Hirotaka Watada

Lipotoxicity-polarised macrophage-derived exosomes regulate mitochondrial fitness through Miro1-mediated mitophagy inhibition and contribute to type 2 diabetes development in mice

Jian-Ming Li, Xianyu Li, Lawrence W. C. Chan, Ruinian Hu, Tian Zheng, Haojie Li, Sijun Yang

Presymptomatic type 1 diabetes and disease severity at onset

Josephine Schneider, Gita Gemulla, Wieland Kiess, Reinhard Berner, Angela Hommel

Presymptomatic type 1 diabetes and disease severity at onset. Reply to Schneider J, Gemulla G, Kiess W et al [letter]

Sandra Hummel, Nadine Friedl, Christiane Winkler, Anette-G. Ziegler, Peter Achenbach