Diabetologia

Up Front

Diabetes and artificial intelligence beyond the closed loop: a review of the landscape, promise and challenges

Scott C. Mackenzie, Chris A. R. Sainsbury, Deborah J. Wake

A narrative commentary about interoperability in medical devices and data used in diabetes therapy from an academic EU/UK/US perspective

Johan Jendle, Peter Adolfsson, Pratik Choudhary, Klemen Dovc, Alexander Fleming, David C. Klonoff, Julia K. Mader, Nick Oliver, Jennifer L. Sherr, Jan Šoupal, Lutz Heinemann

Mineralocorticoid receptor overactivation: targeting systemic impact with non-steroidal mineralocorticoid receptor antagonists

Gianluigi Savarese, Felix Lindberg, Gerasimos Filippatos, Javed Butler, Stefan D. Anker

Early time-restricted carbohydrate consumption vs conventional dieting in type 2 diabetes: a randomised controlled trial

Domenico Tricò, Maria Chiara Masoni, Simona Baldi, Noemi Cimbalo, Luca Sacchetta, Maria Tiziana Scozzaro, Giulia Nesti, Alessandro Mengozzi, Lorenzo Nesti, Martina Chiriacò, Andrea Natali

A diminished sciatic nerve structural integrity is associated with distinct peripheral sensory phenotypes in individuals with type 2 diabetes

Christoph M. Mooshage, Dimitrios Tsilingiris, Lukas Schimpfle, Lukas Seebauer, Omar Eldesouky, Taraneh Aziz-Safaie, Anja Hohmann, Stephan Herzig, Julia Szendroedi, Peter Nawroth, Sabine Heiland, Martin Bendszus, Felix T. Kurz, Stefan Kopf, Johann M. E. Jende, Zoltan Kender

HOMA-IR and the Matsuda Index as predictors of progression to type 1 diabetes in autoantibody-positive relatives

Alessandra Petrelli, Federica Cugnata, Debora Carnovale, Emanuele Bosi, Ingrid M. Libman, Lorenzo Piemonti, David Cuthbertson, Jay M. Sosenko

Hyperglycaemia, diabetes and risk of fragility fractures: observational and Mendelian randomisation studies

Frida Emanuelsson, Shoaib Afzal, Niklas R. Jørgensen, Børge G. Nordestgaard, Marianne Benn

Effects of maternal type 1 diabetes and confounding factors on neonatal microbiomes

Marzena Gajecka, Pawel Gutaj, Katarzyna Jaskiewicz, Malgorzata Rydzanicz, Tomasz Szczapa, Dorota Kaminska, Grzegorz Kosewski, Juliusz Przyslawski, Rafal Ploski, Ewa Wender-Ozegowska

Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas

Sarah Meulebrouck, Victoria Scherrer, Raphaël Boutry, Bénédicte Toussaint, Emmanuel Vaillant, Aurélie Dechaume, Hélène Loiselle, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Michel Marre, Morgane Baron, Martine Vaxillaire, Mehdi Derhourhi, Mathilde Boissel, Philippe Froguel, Amélie Bonnefond

Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention

Emilie Moens de Hase, Audrey M. Neyrinck, Julie Rodriguez, Miriam Cnop, Nicolas Paquot, Jean-Paul Thissen, Yining Xu, Ana Beloqui, Laure B. Bindels, Nathalie M. Delzenne, Matthias Van Hul, Patrice D. Cani

Habitual carbohydrate intake is not correlated with circulating β-hydroxybutyrate levels in pregnant women with overweight and obesity at 28 weeks' gestation

Helen L. Tanner, Hui Ting Ng, Grace Murphy, Helen L. Barrett, Leonie K. Callaway, H. David McIntyre, Marloes Dekker Nitert

RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine

Michael G. Miskelly, Andreas Lindqvist, Elena Piccinin, Alexander Hamilton, Elaine Cowan, Bent-Johnny Nergård, Rita Del Giudice, Mtakai Ngara, Luis R. Cataldo, Dmytro Kryvokhyzha, Petr Volkov, Luke Engelking, Isabella Artner, Jens O. Lagerstedt, Lena Eliasson, Emma Ahlqvist, Antonio Moschetta, Jan Hedenbro, Nils Wierup

Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia

Judit Castillo-Armengol, Flavia Marzetta, Ana Rodriguez Sanchez-Archidona, Christian Fledelius, Mark Evans, Alison McNeilly, Rory J. McCrimmon, Mark Ibberson, Bernard Thorens

High intensity interval training as a novel treatment for impaired awareness of hypoglycaemia in people with type 1 diabetes (HIT4HYPOS): a randomised parallel-group study

Catriona M. Farrell, Alison D. McNeilly, Simona Hapca, Paul A. Fournier, Timothy W. Jones, Andrea Facchinetti, Giacomo Cappon, Daniel J. West, Rory J. McCrimmon

Correction to: Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia

Judit Castillo‑Armengol, Flavia Marzetta, Ana Rodriguez Sanchez-Archidona, Christian Fledelius, Mark Evans, Alison McNeilly, Rory J. McCrimmon, Mark Ibberson, Bernard Thorens