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European Journal of Nuclear Medicine and Molecular Imaging

Erschienen in:

01.04.2011 | Editorial Commentary

Diagnosis and therapy are walking together on radiopeptides’ avenue

verfasst von: Luigi Mansi, Irene Virgolini

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 4/2011

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The paper in this issue by Jiang et al. [1] stimulates a reflection on the state of the art and perspectives in radionuclide therapy, centred on the keyword “peptide”. The authors report their preliminary experience on the production of cystine knot peptides (knottins) 2.5D and 2.5F, engineered to bind with high affinity and specificity to integrin receptors, overexpressed on the surface of a variety of malignant human tumour cells and tumour neovasculature. In this study, 2.5D and 2.5F were successfully labelled with ¹⁷⁷Lu, representing potential therapeutic agents in a murine model of human glioma xenografts. …

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10.

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Titel: Diagnosis and therapy are walking together on radiopeptides’ avenue
verfasst von: Luigi Mansi
Irene Virgolini
Publikationsdatum: 01.04.2011
Verlag: Springer-Verlag
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 4/2011
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-011-1762-8

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Diagnosis and therapy are walking together on radiopeptides’ avenue

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