Background
Methods
Study populations
CAC-scoring CT and assessment of Agatston score
Measurement of abdominal and cardiac adipose tissue by CT
Characteristics of metabolic syndrome components
Statistical analysis
Results
Clinical characteristics of the study participants
Age (years) | 54.94 ± 9.05 |
---|---|
Men (male) | 79 % |
Waist circumference (cm) | 89.17 ± 8.90 |
BMI (kg/m2) | 24.90 ± 3.36 |
HDL-C (mg/dL) | 41 (18, 201) |
Triglycerides (mg/dL) | 130 (44, 2182) |
Diabetes mellitus (%) | 23 % |
Current smokers (%) | 45 % |
Hypertension (%) | 40 % |
Number of metabolic components | 2.35 ± 1.32 |
Agatston score | 8.50 (44,2182) |
Total volume of AVAT (mm3) | 1129.09 ± 530.62 |
Total volume of PAT (mm3) | 219.29 ± 90.02 |
Total volume of EAT (mm3) | 121.33 ± 45.65 |
EATth-LAVG (mm) | 15.92 ± 4.47 |
EATth-RAVG (mm) | 17.08 ± 3.74 |
EATth-AIVG (mm) | 8.36 ± 10.96 |
Correlations between cardiometabolic risk and adipose tissue measurements
Pearson correlation coefficients between cardiometabolic risk and adipose Tissue measurements
BMI | Waist circumference | Metabolic syndrome components | Agatston score on a four ranking scale | Agatston score | |
---|---|---|---|---|---|
Total volume of AVAT | 0.706**
| 0.775**
| 0.519**
| 0.169*
| 0.064 |
Total volume of PAT | 0.529**
| 0.629**
| 0.382**
| 0.250**
| 0.109 |
Total volume of EAT | 0.487**
| 0.526**
| 0.264**
| 0.127 | 0.083 |
EATth-LAVG | 0.275**
| 0.239**
| 0.250**
| 0.307**
| 0.287**
|
EATth-RAVG | 0.059**
| 0.116 | −0.014 | 0.046 | 0.100 |
EATth-AIVG | 0.052**
| 0.074 | 0.052 | −0.060 | −0.019 |
Clustering of cardiometabolic risk factors: factor analysis
Characteristic | Factor 1 | Factor 2 |
---|---|---|
Waist circumference | 0.881 | −0.156 |
BMI | 0.841 | −0.228 |
Metabolic components | 0.570 | 0.188 |
Agatston score | 0.157 | 0.823 |
Total volume of AVAT | 0.890 | −0.136 |
Total volume of PAT | 0.809 | 0.059 |
Total volume of EAT | 0.702 | −0.046 |
EATth-LAVG | 0.467 | 0.629 |
Percentage of total variance explained | 49.91 | 15.10 |
Cumulative % | 49.91 | 65.01 |
Abdominal or cardiac adiposity in cardiometabolic risk factors
Predictora
| OR | 95 % CI |
P value |
---|---|---|---|
Age (years) | 1.039 | 0.996–1.084 | .074 |
Gender (male) | 0.196 | 0.063–0.614 | .154 |
Waist circumference (cm) | 1.010 | 0.963–1.067 | .051 |
Total volume of AVAT (mm3) | 1.200 | 1.080–1.320 | <0.001 |
Total volume of PAT (mm3) | 1.002 | 0.991–1.013 | .747 |
Total volume of EAT (mm3) | 0.995 | 0.984–1.006 | .378 |
EATth-LAVG (mm) | 0.954 | 0.871–1.046 | .316 |
Predictora
| OR | 95 % CI |
P value |
---|---|---|---|
Age (years) | 1.10 | 1.065–1.143 | <0.001 |
Gender (male) | 0.18 | 0.070–0.496 | .001 |
Waist circumference (cm) | 1.02 | 0.966–1.070 | .528 |
Hypertension | 0.56 | 0.314–0.979 | .059 |
Diabetes mellitus | 0.46 | 0.237–0.912 | .026 |
HDL-C (mg/dL) | 0.99 | 0.979–1.018 | .858 |
Triglycerides (mg/dL) | 1.00 | 0.998–1.002 | .863 |
Current smokers | 0.93 | 0.508–1.707 | .819 |
Total volume of AVAT (mm3) | 0.99 | 0.998–1.000 | .303 |
Total volume of PAT (mm3) | 0.99 | 0.999–1.015 | .088 |
Total volume of EAT (mm3) | 0.99 | 0.986–1.002 | .142 |
EATth-LAVG (mm) | 1.11 | 1.034–1.184 | .004 |