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Erschienen in: Current Geriatrics Reports 1/2023

22.11.2022 | Cardiovascular Disease in the Elderly (M Chen, Section Editor)

Disparities in Heart Failure Management in Older Adults

verfasst von: Ryan C. Martin, MD

Erschienen in: Current Geriatrics Reports | Ausgabe 1/2023

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Abstract

Purpose of the Review:

Patients with a heart failure diagnosis face early mortality and impaired quality of life. Optimal management requires close follow up and appropriate management of guideline-directed medial therapy (GDMT). The purpose of this review is to identify the sources of outcome disparities amongst elderly patients with heart failure, examine which can be acted upon, and propose potential measures to improve care moving forward.

Recent Findings:

Disparities in heart failure outcomes have been observed in comparing the older population to the younger, in blacks or Hispanics vs. whites, and in male vs. female patients. Many disparities on further analysis in recent studies has revealed common causes amongst these groups. Underutilization of GDMT is a major driver of worse outcomes and prognosis. In addition, many disparities previously attributed to race have their underlying cause in access to heart failure-specialized care in lower socioeconomic regions. Lastly, uncontrolled comorbidities, particularly kidney disease, chronic obstructive pulmonary disease (COPD), depression, and atrial fibrillation are associated with worse outcomes and are more prevalent with advancing age, blacks, and men.

Summary:

Disparities in HF management are a result of underutilization of GDMT, limited access to care in low socioeconomic status or rural areas, and uncontrolled comorbidities. Improving care in this population requires a broad approach including community based clinics or partnerships with established primary care offices, protocols for GDMT initiation and dose adjustments, and comprehensive management of not only heart failure but a patient’s other comorbidities.
Literatur
3.
Zurück zum Zitat Matusik P, Dubiel M, Wizner B, Fedyk-Łukasik M, Zdrojewski T, Opolski G, et al. Age-related gap in the management of heart failure patients. The National Project of Prevention and Treatment of Cardiovascular Diseases POLKARD. Cardiology Journal. 2012;19(2):146 − 52. Matusik P, Dubiel M, Wizner B, Fedyk-Łukasik M, Zdrojewski T, Opolski G, et al. Age-related gap in the management of heart failure patients. The National Project of Prevention and Treatment of Cardiovascular Diseases POLKARD. Cardiology Journal. 2012;19(2):146 − 52.
7.
Zurück zum Zitat ● Chen X, Cui X, Thunström E, Pivodic A, Dahlström U, Fu M. Guideline-directed medical therapy in real-world heart failure patients with low blood pressure and renal dysfunction. Clinical Research in Cardiology. 2021;110(7):1051-62. This study questions the historical reluctance to avoid aggressive GDMT titration in the older population. By examining GDMT usage in those with borderline hypotension (SBP ≤ 100 mmHg) and renal dysfunciton (eGFR ≤ 60), Chen et al. demonstrate the survival benefit of being on BB, ACEI/ARB/ARNI, and MRA.https://doi.org/10.1007/s00392-020-01790-y ● Chen X, Cui X, Thunström E, Pivodic A, Dahlström U, Fu M. Guideline-directed medical therapy in real-world heart failure patients with low blood pressure and renal dysfunction. Clinical Research in Cardiology. 2021;110(7):1051-62. This study questions the historical reluctance to avoid aggressive GDMT titration in the older population. By examining GDMT usage in those with borderline hypotension (SBP ≤ 100 mmHg) and renal dysfunciton (eGFR ≤ 60), Chen et al. demonstrate the survival benefit of being on BB, ACEI/ARB/ARNI, and MRA.https://​doi.​org/​10.​1007/​s00392-020-01790-y
11.
Zurück zum Zitat ● Ziaeian B, Heidenreich PA, Xu H, DeVore AD, Matsouaka RA, Hernandez AF, et al. Medicare Expenditures by Race/Ethnicity After Hospitalization for Heart Failure With Preserved Ejection Fraction. JACC: Heart Failure. 2018;6(5):388 – 97. By using Medicare expenditure data, this analysis deftly highlighted the impact of underlying socioeconomic status on outcomes, as reflected in inpatient care costs derived from index admissions and subsequent readmissions.https://doi.org/10.1016/j.jchf.2017.12.007 ● Ziaeian B, Heidenreich PA, Xu H, DeVore AD, Matsouaka RA, Hernandez AF, et al. Medicare Expenditures by Race/Ethnicity After Hospitalization for Heart Failure With Preserved Ejection Fraction. JACC: Heart Failure. 2018;6(5):388 – 97. By using Medicare expenditure data, this analysis deftly highlighted the impact of underlying socioeconomic status on outcomes, as reflected in inpatient care costs derived from index admissions and subsequent readmissions.https://​doi.​org/​10.​1016/​j.​jchf.​2017.​12.​007
15.
Zurück zum Zitat Mathews L, Ding N, Mok Y, Shin JI, Crews DC, Rosamond WD, et al. Impact of Socioeconomic Status on Mortality and Readmission in Patients With Heart Failure With Reduced Ejection Fraction: The ARIC Study. J Am Heart Association. 2022;11(18). https://doi.org/10.1161/jaha.121.024057 Mathews L, Ding N, Mok Y, Shin JI, Crews DC, Rosamond WD, et al. Impact of Socioeconomic Status on Mortality and Readmission in Patients With Heart Failure With Reduced Ejection Fraction: The ARIC Study. J Am Heart Association. 2022;11(18). https://​doi.​org/​10.​1161/​jaha.​121.​024057
20.
Zurück zum Zitat ● Lainščak M, Milinković I, Polovina M, Crespo-Leiro MG, Lund LH, Anker SD, et al. Sex‐ and age‐related differences in the management and outcomes of chronic heart failure: an analysis of patients from the ESC HFA EORP Heart Failure Long‐Term Registry. European Journal of Heart Failure. 2020;22(1):92–102 This study utilized a large volume registry to effectively identify and adjust for confounders in the discrepancy in HF outcomes between men and women.https://doi.org/10.1002/ejhf.1645 ● Lainščak M, Milinković I, Polovina M, Crespo-Leiro MG, Lund LH, Anker SD, et al. Sex‐ and age‐related differences in the management and outcomes of chronic heart failure: an analysis of patients from the ESC HFA EORP Heart Failure Long‐Term Registry. European Journal of Heart Failure. 2020;22(1):92–102 This study utilized a large volume registry to effectively identify and adjust for confounders in the discrepancy in HF outcomes between men and women.https://​doi.​org/​10.​1002/​ejhf.​1645
Metadaten
Titel
Disparities in Heart Failure Management in Older Adults
verfasst von
Ryan C. Martin, MD
Publikationsdatum
22.11.2022
Verlag
Springer US
Erschienen in
Current Geriatrics Reports / Ausgabe 1/2023
Elektronische ISSN: 2196-7865
DOI
https://doi.org/10.1007/s13670-022-00378-w

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