Skip to main content
Erschienen in: Journal of General Internal Medicine 11/2009

01.11.2009 | Editorial

Don’t Be ‘Mis-led’: Few Herbal Products have Been Implicated in Lead Poisoning

verfasst von: Adriane Fugh-Berman, MD

Erschienen in: Journal of General Internal Medicine | Ausgabe 11/2009

Einloggen, um Zugang zu erhalten

Excerpt

The Beuttner study1 in this issue of JGIM used NHANES data to draw an association between lead levels and the use of herbal supplements, but the findings should raise more caution about interpretations than herbs. Although geometric means of blood lead levels were 10% higher among women who used herbs, compared to nonusers, all geometric means were low. Only 0.6% of the population had elevated (>10 mcg/dL) blood levels and the authors provide no evidence that elevated lead levels were more common in users of herbs. Increased lead levels, even if statistically significant, are of questionable clinical significance when levels remain in the low-normal range. As the authors note, men had higher blood lead levels than women, and although the use of supplements was similar in men and women, no association between lead levels and herb use was found among men. …
Literatur
1.
Zurück zum Zitat Buettner C, Mukamal KJ, Gardiner P, Davis RB, Phillips RS, Mittleman MA. Herbal supplement use and blood lead levels of united states adults. J Gen Intern Med. 2009, Jul 3. doi:10.1007/s11606-009-1050-5. Buettner C, Mukamal KJ, Gardiner P, Davis RB, Phillips RS, Mittleman MA. Herbal supplement use and blood lead levels of united states adults. J Gen Intern Med. 2009, Jul 3. doi:10.​1007/​s11606-009-1050-5.
7.
Zurück zum Zitat Kang-Yum E, Oransky SH. Chinese patent medicine as a potential source of mercury poisoning. Vet Hum Toxicol. 1992;34(3):235–8. Jun.PubMed Kang-Yum E, Oransky SH. Chinese patent medicine as a potential source of mercury poisoning. Vet Hum Toxicol. 1992;34(3):235–8. Jun.PubMed
8.
Zurück zum Zitat Dilda PJ, Hogg PJ. Arsenical-based cancer drugs. Cancer Treat Rev. 2007;33(6):542–64. Epub 2007 Jul 10, Oct.CrossRefPubMed Dilda PJ, Hogg PJ. Arsenical-based cancer drugs. Cancer Treat Rev. 2007;33(6):542–64. Epub 2007 Jul 10, Oct.CrossRefPubMed
9.
Zurück zum Zitat Salt DE, Blaylock M, Kumar NPBA, et al. Phytoremediation: a novel strategy for the removal of toxic metals from the environment using plants. Biotechnoolgy. 1995;13:468–74.CrossRef Salt DE, Blaylock M, Kumar NPBA, et al. Phytoremediation: a novel strategy for the removal of toxic metals from the environment using plants. Biotechnoolgy. 1995;13:468–74.CrossRef
10.
Zurück zum Zitat López ML, Peralta-Videa JR, Benitez T, Gardea-Torresdey JL. Enhancement of lead uptake by alfalfa (Medicago sativa) using EDTA and a plant growth promoter. Chemosphere. 2005;61(4):595–8. Epub 2005 Apr 7, Oct.CrossRefPubMed López ML, Peralta-Videa JR, Benitez T, Gardea-Torresdey JL. Enhancement of lead uptake by alfalfa (Medicago sativa) using EDTA and a plant growth promoter. Chemosphere. 2005;61(4):595–8. Epub 2005 Apr 7, Oct.CrossRefPubMed
11.
Zurück zum Zitat Salido AL, Hasty KL, Lim JM, Butcher DJ. Phytoremediation of arsenic and lead in contaminated soil using Chinese brake ferns (Pteris vittata) and Indian mustard (Brassica juncea). Int J Phytoremediat. 2003;5(2):89–103.CrossRef Salido AL, Hasty KL, Lim JM, Butcher DJ. Phytoremediation of arsenic and lead in contaminated soil using Chinese brake ferns (Pteris vittata) and Indian mustard (Brassica juncea). Int J Phytoremediat. 2003;5(2):89–103.CrossRef
12.
Zurück zum Zitat Pourjafar M, Aghbolaghi PA, Shakhse-Niaie M. Effect of garlic along with lead acetate administration on lead burden of some tissues in mice. Pak J Biol Sci. 2007;10(16):2772–4. Aug 15.CrossRefPubMed Pourjafar M, Aghbolaghi PA, Shakhse-Niaie M. Effect of garlic along with lead acetate administration on lead burden of some tissues in mice. Pak J Biol Sci. 2007;10(16):2772–4. Aug 15.CrossRefPubMed
13.
Zurück zum Zitat Pourjafar M, Aghbolaghi PA, Shakhse-Niaie M, et al. Garlic (Allium sativum L.) as a potential antidote for cadmium and lead intoxication: cadmium and lead distribution and analysis in different miceorgans. Biol Trace Elem Res. 2007;120(1–3):227–34. Winter. Pourjafar M, Aghbolaghi PA, Shakhse-Niaie M, et al. Garlic (Allium sativum L.) as a potential antidote for cadmium and lead intoxication: cadmium and lead distribution and analysis in different miceorgans. Biol Trace Elem Res. 2007;120(1–3):227–34. Winter.
14.
Zurück zum Zitat Senapati SK, Dey S, Dwivedi SK, Swarup D. Effect of garlic (Allium sativum L.) extract on tissue lead level in rats. J Ethnopharmacol. 2001;76(3):229–32. Aug.CrossRefPubMed Senapati SK, Dey S, Dwivedi SK, Swarup D. Effect of garlic (Allium sativum L.) extract on tissue lead level in rats. J Ethnopharmacol. 2001;76(3):229–32. Aug.CrossRefPubMed
15.
Zurück zum Zitat Najar-Nezhad V, Aslani MR, Balali-Mood M. Evaluation of allicin for the treatment of experimentally induced subacute lead poisoning in sheep. Biol Trace Elem Res. 2008;126(1–3):141–7. Winter.CrossRefPubMed Najar-Nezhad V, Aslani MR, Balali-Mood M. Evaluation of allicin for the treatment of experimentally induced subacute lead poisoning in sheep. Biol Trace Elem Res. 2008;126(1–3):141–7. Winter.CrossRefPubMed
16.
Zurück zum Zitat Aga M, Iwaki K, Ueda Y, et al. Preventive effect of Coriandrum sativum (Chinese parsley) on localized leaddeposition in ICR mice. J Ethnopharmacol. 2001;77(2–3):203–8. Oct.CrossRefPubMed Aga M, Iwaki K, Ueda Y, et al. Preventive effect of Coriandrum sativum (Chinese parsley) on localized leaddeposition in ICR mice. J Ethnopharmacol. 2001;77(2–3):203–8. Oct.CrossRefPubMed
17.
Zurück zum Zitat Ettinger AS, Lamadrid-Figueroa H, Téllez-Rojo MM, et al. Effect of calcium supplementation on blood lead levels in pregnancy: a randomized placebo-controlled trial. Environ Health Perspect. 2009;117(1):26–31. Jan.PubMed Ettinger AS, Lamadrid-Figueroa H, Téllez-Rojo MM, et al. Effect of calcium supplementation on blood lead levels in pregnancy: a randomized placebo-controlled trial. Environ Health Perspect. 2009;117(1):26–31. Jan.PubMed
18.
Zurück zum Zitat Lamadrid-Figueroa H, Téllez-Rojo MM, Mercado-García A, et al. Effect of calcium supplementation on blood lead levels in pregnancy: a randomized placebo-controlled trial. Environ Health Perspect. 2009;117(1):26–31. Jan.PubMed Lamadrid-Figueroa H, Téllez-Rojo MM, Mercado-García A, et al. Effect of calcium supplementation on blood lead levels in pregnancy: a randomized placebo-controlled trial. Environ Health Perspect. 2009;117(1):26–31. Jan.PubMed
19.
Zurück zum Zitat Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology. 2003;14(2):206–12. Mar.CrossRefPubMed Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology. 2003;14(2):206–12. Mar.CrossRefPubMed
Metadaten
Titel
Don’t Be ‘Mis-led’: Few Herbal Products have Been Implicated in Lead Poisoning
verfasst von
Adriane Fugh-Berman, MD
Publikationsdatum
01.11.2009
Verlag
Springer-Verlag
Erschienen in
Journal of General Internal Medicine / Ausgabe 11/2009
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-009-1106-6

Weitere Artikel der Ausgabe 11/2009

Journal of General Internal Medicine 11/2009 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Die „Zehn Gebote“ des Endokarditis-Managements

30.04.2024 Endokarditis Leitlinie kompakt

Worauf kommt es beim Management von Personen mit infektiöser Endokarditis an? Eine Kardiologin und ein Kardiologe fassen die zehn wichtigsten Punkte der neuen ESC-Leitlinie zusammen.

Strenge Blutdruckeinstellung lohnt auch im Alter noch

30.04.2024 Arterielle Hypertonie Nachrichten

Ältere Frauen, die von chronischen Erkrankungen weitgehend verschont sind, haben offenbar die besten Chancen, ihren 90. Geburtstag zu erleben, wenn ihr systolischer Blutdruck < 130 mmHg liegt. Das scheint selbst für 80-Jährige noch zu gelten.

Frauen bekommen seltener eine intensive Statintherapie

30.04.2024 Statine Nachrichten

Frauen in den Niederlanden erhalten bei vergleichbarem kardiovaskulärem Risiko seltener eine intensive Statintherapie als Männer. Ihre LDL-Zielwerte erreichen sie aber fast ähnlich oft.

Reizdarmsyndrom: Diäten wirksamer als Medikamente

29.04.2024 Reizdarmsyndrom Nachrichten

Bei Reizdarmsyndrom scheinen Diäten, wie etwa die FODMAP-arme oder die kohlenhydratreduzierte Ernährung, effektiver als eine medikamentöse Therapie zu sein. Das hat eine Studie aus Schweden ergeben, die die drei Therapieoptionen im direkten Vergleich analysierte.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.