Erschienen in:
21.10.2020 | Original Research
Dosimetric evaluation of a rotating gamma-ray system for stereotactic body radiation therapy
verfasst von:
Ahmed Eldib, Muhammad Fareed, Stephanie Weiss, Shelly Hayes, Binh Nguyen, Grisel Mora, Jinsheng Li, Omar Chibani, Mahmoud Abdelgawad, C-M. Charlie Ma
Erschienen in:
Journal of Radiation Oncology
|
Ausgabe 3-4/2020
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Abstract
Purpose
Gamma-ray stereotactic radiosurgery systems available commercially contain either stationary or rotational source configuration. Rotational systems reduce the number of sources utilized and can also provide beneficial dosimetric properties. In this study, we explore the dosimetric advantage of a novel rotating gamma-ray design for stereotactic body radiotherapy (SBRT) as compared to the well-established CyberKnife system.
Materials and methods
CybeRay (OUR United Corp., Xian, China) is a rotating gamma-ray system (RGS). Its treatment head can rotate 360° in the axial plane and swing 35° in the superior direction. It includes 13 Co-60 sources focusing on the isocenter. The RT Pro planning system (Prowess, Concord, CA) was used for CybeRay treatment planning, while the Multiplan software (Accuray, Sunnyvale, CA) was used for CyberKnife treatment planning. Twelve SBRT patients previously treated with CyberKnife were re-planned for CybeRay, and their treatment plans were compared based on isodose distributions, dose volume histograms, conformity index (CI), and the estimated treatment time.
Results
The planning target volume ranged from 4.4 to 124.2 cc. Both treatment systems provided excellent SBRT plans that meet our clinical acceptance criteria. The mean value of CI was 1.25 for both CyberKnife and CybeRay (p = 0.03). The estimated treatment delivery time for the CyberKnife plans ranged from 13 to 53 min as compared to 6 to 54 min with CybeRay (p = 0.02). CybeRay was superior concerning peripheral doses appearing as excessive isodose lines extending to distal normal tissues.
Conclusion
The new CybeRay machine showed promising dosimetric capabilities for stereotactic radiosurgery and radiotherapy of extra- and intra-cranial lesions.