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Erschienen in: Current Treatment Options in Oncology 8/2019

01.08.2019 | Breast Cancer (EA Comen, Section Editor)

Emerging Role of Genomics and Cell-Free DNA in Breast Cancer

verfasst von: Lorenzo Gerratana, MD, Andrew A. Davis, MD, Ami N. Shah, MD, Chenyu Lin, MD, Carla Corvaja, MD, Massimo Cristofanilli, MD, FACP

Erschienen in: Current Treatment Options in Oncology | Ausgabe 8/2019

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Opinion statement

Precision Medicine is gaining momentum as the future gold standard healthcare strategy as it enables treatment optimization and consequently a potential improvement for quality of life and survival. This paradigm shift was possible thanks to new high-throughput genomics technologies, which provide prognostic and predictive information on tumor biology and potential treatment options, as standard pathological procedures are unable to capture both spatial and temporal tumor heterogeneity. As a result of decreasing costs, both solid and liquid-based genomics have an increasingly important role in clinical trials’ screening procedures and are gradually being incorporated into clinical practice. Notwithstanding the great potential, its clinical utility is still a matter of debate and clinicians need to be aware of caveats in interpreting resulting data.
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Metadaten
Titel
Emerging Role of Genomics and Cell-Free DNA in Breast Cancer
verfasst von
Lorenzo Gerratana, MD
Andrew A. Davis, MD
Ami N. Shah, MD
Chenyu Lin, MD
Carla Corvaja, MD
Massimo Cristofanilli, MD, FACP
Publikationsdatum
01.08.2019
Verlag
Springer US
Erschienen in
Current Treatment Options in Oncology / Ausgabe 8/2019
Print ISSN: 1527-2729
Elektronische ISSN: 1534-6277
DOI
https://doi.org/10.1007/s11864-019-0667-9

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