Epidemiological Study of Gallbladder Cancer Patients from North Indian Gangetic Planes—a High-Volume Centre’s Experience

The peak incidence of GBC was in 31–50 years age group (58 %). Male to female ratio was 1:4.83, with mean age for females (mean 49.1 years) significantly lower than male counterpart (mean 54.9 years) (p value = 0.000423). Majority of patients were non-vegetarians (67 %) and 84 % of them consumed mustard oil (home made/loose packed) as predominant cooking medium. Majority of the patients of GBC in our study were from low socioeconomic strata (68 %) (Kuppuswamy classes IV, V (lower class)). GBC was more commonly seen in females with the age of menarche less than 14 years (83 %) and the age of the first child birth less than 20 years (56 %). Females with more than two children had higher incidence (57 %). Majority of the female patients (71 %) were postmenopausal. Gallstones were present in 390 out of 490 patients (80 %). Incidental gallbladder carcinoma was detected in 158 out of 490 patients (32 %). Pain abdomen was the most common presenting complaint (98 %). Significant proportion of the patients with GBC presented with distant metastasis (stage IVB) (52 %). The most common histological subtype was adenocarcinoma (78 %).