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Erschienen in: Breast Cancer Research 1/1999

01.12.1999 | Commentary

Epithelial stem cells in the mammary gland: casting light into dark corners

verfasst von: Elizabeth Anderson, Robert B Clarke

Erschienen in: Breast Cancer Research | Ausgabe 1/1999

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Abstract

The epithelial structures of the human breast or the mouse mammary gland are derived from a relatively small number of multipotent, tissue-specific stem cells, of which we are surprisingly ignorant. We do not know how many are required to produce a complete mammary gland, how many times they divide during the process, where they are situated in the gland, or even what they look like. We want to know the answers to these questions, not just to satisfy intellectual curiosity, but also because the answers may shed light on the evolution of breast cancer. Now, studies carried out by Kordon and Smith at the National Cancer Institute have pointed the way toward a new understanding of mammary stem cells and their progeny.
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Metadaten
Titel
Epithelial stem cells in the mammary gland: casting light into dark corners
verfasst von
Elizabeth Anderson
Robert B Clarke
Publikationsdatum
01.12.1999
Verlag
BioMed Central
Erschienen in
Breast Cancer Research / Ausgabe 1/1999
Elektronische ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr5

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