nach oben

Erschienen in:

12.10.2021 | Original Article

Erbium, chromium-doped: yttrium, scandium, gallium, garnet and diode lasers in the treatment of peri‐implantitis: clinical and biochemical outcomes in a randomized-controlled clinical trial

verfasst von: Nazli Zeynep Alpaslan Yayli, Ahmet Cemil Talmac, Serap Keskin Tunc, Damla Akbal, Dicle Altindal, Abdullah Seckin Ertugrul

Erschienen in: Lasers in Medical Science | Ausgabe 1/2022

Einloggen, um Zugang zu erhalten

Abstract

This study aims to evaluate the effects of 940 nm diode laser and 2780 nm erbium, chromium-doped: yttrium, scandium, gallium, garnet (Er,Cr:YSGG) laser used in addition to mechanical therapy in the non-surgical treatment of peri-implantitis on clinical parameters and matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) levels in the peri-implant crevicular fluid. A total of 50 patients with peri-implantitis were randomized into three groups to receive peri-implant treatment. The control group (n = 17) only received conventional non-surgical mechanical therapy. The trial groups [(diode group (n = 16) and Er,Cr:YSGG group (n = 17)] received dental laser in addition to mechanical therapy. Gingival index (GI), plaque index (PI), bleeding on probing, probing depth (PD), MMP-9, and TIMP-1 levels were assessed at baseline (T0) and at 6 months after treatment (T1). The GI, PI, and PD significantly decreased in all groups at T1, compared to T0 (p < 0.05). The decrease in the PD was similar between the control and diode groups with Er,Cr:YSGG providing more reduction (1.16 ± 0.64 mm) than either method (p = 0.032). A significant intra-group decrease in MMP-9 level was only observed in the Er,Cr:YSGG group (p = 0.009). The decrease in TIMP-1 level from T0 to T1 was similar between the control and the diode groups (p > 0.05) and it was significantly lower than the decrease in the Er,Cr:YSGG group (p < 0.05). Addition of diode laser to non-surgical mechanical therapy does not provide any additional benefit for treatment outcomes. The Er,Cr:YSGG laser seems to be more efficient both at clinical and molecular levels. ClinicalTrials, ID: NCT04730687. Registered 13 April 2021. Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04730687

Sinjab K, Garaicoa-Pazmino C, Wang H-L (2018) Decision making for management of periimplant diseases. Implant Dent 27(3):276–281. https://doi.org/10.1097/ID.0000000000000775CrossRefPubMed

Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, Chen S, Cochran D, Derks J, Figuero E, Hämmerle CHF, Heitz-Mayfield LJA, Huynh-Ba G, Iacono V, Koo KT, Lambert F, McCauley L, Quirynen M, Renvert S, Salvi GE, Schwarz F, Tarnow D, Tomasi C, Wang HL, Zitzmann N (2018) Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 world workshop on the classification of periodontal and peri-Implant diseases and conditions. J Clin Periodontol 45(20):286–291. https://doi.org/10.1111/jcpe.12957CrossRef

Mailoa J, Lin G-H, Chan H-L, MacEachern M, Wang H-L (2014) Clinical outcomes of using lasers for peri-implantitis surface detoxification: a systematic review and meta-analysis. J Periodontol 85(9):1194–1202. https://doi.org/10.1902/jop.2014.130620CrossRefPubMed

Teughels W, Van Assche N, Sliepen I, Quirynen M (2006) Effect of material characteristics and/or surface topography on biofilm development. Clin Oral Implant Res 17(2):68–81. https://doi.org/10.1111/j.1600-0501.2006.01353.xCrossRef

Mizutani K, Aoki A, Coluzzi D, Yukna R, Wang CY, Pavlic V (2000) Izumi, Y (2016) Lasers in minimally invasive periodontal and peri-implant therapy. Periodontol 71(1):185–212. https://doi.org/10.1111/prd.12123CrossRef

Świder K, Dominiak M, Grzech-Leśniak K, Matys J (2019) Effect of different laser wavelengths on periodontopathogens in peri-implantitis: a review of in vivo studies. Microorganisms 7(7):189. https://doi.org/10.3390/microorganisms7070189CrossRefPubMedCentral

Aoki A, Mizutani K, Takasaki AA, Sasaki KM, Nagai S, Schwarz F, Yoshida I, Eguro T, Zeredo JL, Izumi Y (2008) Current status of clinical laser applications in periodontal therapy. Gen Dent 56(7):674–687PubMed

Gokhale SR, Padhye AM, Byakod G, Jain SA, Padbidri V, Shivaswamy S (2012) A comparative evaluation of the efficacy of diode laser as an adjunct to mechanical debridement versus conventional mechanical debridement in periodontal flap surgery: a clinical and microbiological study. Photomed Laser Surg 30(10):598–603. https://doi.org/10.1089/pho.2012.3252CrossRefPubMed

Gonçalves F, Zanetti AL, Zanetti RV, Martelli FS, Avila-Campos MJ, Tomazinho LF, Granjeiro JM (2010) Effectiveness of 980-mm diode and 1064-nm extra-long-pulse neodymium-doped yttrium aluminum garnet lasers in implant disinfection. Photomed Laser Surg 28(2):273–280. https://doi.org/10.1089/pho.2009.2496CrossRefPubMed

10.

Albaker AM, ArRejaie AS, Alrabiah M, Abduljabbar T (2018) Effect of photodynamic and laser therapy in the treatment of peri-implant mucositis: a systematic review. Photodiagnosis Photodyn Ther 21:147–152. https://doi.org/10.1016/j.pdpdt.2017.11.011CrossRefPubMed

11.

Aimetti M, Mariani GM, Ferrarotti F, Ercoli E, Liu CC, Romano F (2019) Adjunctive efficacy of diode laser in the treatment of peri-implant mucositis with mechanical therapy: a randomized clinical trial. Clin Oral Implants Res 30(5):429–438. https://doi.org/10.1111/clr.13428CrossRefPubMed

12.

Norton MR (2017) Efficacy of Er:YAG laser in the decontamination of peri-implant disease: a one-year prospective closed cohort study. Int J Periodontics Restorative Dent 37(6):781–788. https://doi.org/10.11607/prd.3324CrossRefPubMed

13.

Alassy H, Parachuru P, Wolff L (2019) Peri-implantitis diagnosis and prognosis using biomarkers in peri-implant crevicular fluid: a narrative review. Diagnostics 9(4):214. https://doi.org/10.3390/diagnostics9040214CrossRefPubMedCentral

14.

Corrêa MG, Pimentel SP, Ribeiro FV, Cirano FR, Casati MZ (2019) Host response and peri-implantitis. Braz Oral Res 33(1):e066. https://doi.org/10.1590/1807-3107bor-2019.vol33.0066CrossRefPubMed

15.

Emecen-Huja P, Eubank TD, Shapiro V, Yildiz V, Tatakis DN, Leblebicioglu B (2013) Peri-implant versus periodontal wound healing. J Clin Periodontol 40(8):816–824. https://doi.org/10.1111/jcpe.12127CrossRefPubMedPubMedCentral

16.

Moher D, Hopewell S, Schulz KF, Montori V, Gøtzsche P, Devereaux PJ, Elbourne D, Egger M, Altman DG, Consolidated Standards of Reporting Trials Group (2010) CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol 63(8):1–37. https://doi.org/10.1016/j.jclinepi.2010.03.004CrossRef

17.

Renvert S, Persson GR, Pirih FQ, Camargo PM (2018) Peri-implant health, peri-implant mucositis, and peri-implantitis: case definitions and diagnostic considerations. J Periodontol 89(1):304–312. https://doi.org/10.1002/JPER.17-0588CrossRef

18.

Silness J, Löe H (1964) Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condtion. Acta Odontol Scand 22:121–135. https://doi.org/10.3109/00016356408993968CrossRefPubMed

19.

Löe H, Silness J (1963) Periodontal disease in pregnancy. I Prevalence and severity. Acta Odontol Scand 21:533–551. https://doi.org/10.3109/00016356309011240CrossRefPubMed

20.

Ainamo J, Bay I (1975) Problems and proposals for recording gingivitis and plaque. Int Dent J 25(4):229–235PubMed

21.

Arisan V, Karabuda ZC, Arici SV, Topcuoglu N, Kulekci G (2015) A randomized clinical trial of an adjunct diode laser application for the nonsurgical treatment of peri-implantitis. Photomed Laser Surg 33(11):547–554. https://doi.org/10.1089/pho.2015.3956CrossRefPubMedPubMedCentral

22.

Castro GL, Gallas M, Núñez IR, Borrajo JLL, Álvarez JC, Varela LG (2007) Scanning electron microscopic analysis of diode laser-treated titanium implant surfaces. Photomed Laser Surg 25(2):124–128. https://doi.org/10.1089/pho.2006.1086CrossRefPubMed

23.

Birang E, TalebiArdekani MR, Rajabzadeh M, Sarmadi G, Birang R, Gutknecht N (2017) Evaluation of effectiveness of photodynamic therapy with low-level diode laser in nonsurgical treatment of peri-implantitis. J Lasers Med Sci 8(3):136–142. https://doi.org/10.15171/jlms.2017.25CrossRefPubMedPubMedCentral

24.

Kotsakis GA, Konstantinidis I, Karoussis IK, Ma X, Chu H (2014) Systematic review and meta-analysis of the effect of various laser wavelengths in the treatment of peri-implantitis. J Periodontol 85(9):1203–1213. https://doi.org/10.1902/jop.2014.130610CrossRefPubMed

25.

Al-Falaki R, Cronshaw M, Hughes FJ (2014) Treatment outcome following use of the erbium, chromium:yttrium, scandium, gallium, garnet laser in the non-surgical management of peri-implantitis: a case series. Br Dent J 217(8):453–457. https://doi.org/10.1038/sj.bdj.2014.910CrossRefPubMed

26.

Yao WL, Lin J, Salamanca E, Pan YH, Tsai PY, Leu SJ, Yang KC, Huang HM, Huang HY, Chang WJ (2020) Er, Cr:YSGG laser performance improves biological response on titanium surfaces. Materials (Basel) 13(3):756. https://doi.org/10.3390/ma13030756CrossRef

27.

Lerario F, Roncati M, Gariffo A, Attorresi E, Lucchese A, Galanakis A, Palaia G, Romeo U (2016) Non-surgical periodontal treatment of peri-implant diseases with the adjunctive use of diode laser: preliminary clinical study. Lasers Med Sci 31(1):1–6. https://doi.org/10.1007/s10103-015-1785-7CrossRefPubMed

28.

Strever JM, Lee J, Ealick W, Peacock M, Shelby D, Susin C, Mettenberg D, El-Awady A, Rueggeberg F, Cutler CW (2017) Erbium, chromium:yttrium-scandium-gallium-garnet laser effectively ablates single-species biofilms on titanium disks without detectable surface damage. J Periodontol 88(5):484–492. https://doi.org/10.1902/jop.2016.160529CrossRefPubMed

29.

Miller RJ (2004) Treatment of the contaminated implant surface using the Er, Cr:YSGG laser. Implant Dent 13(2):165–170. https://doi.org/10.1097/01.id.0000127521.06443.0bCrossRefPubMed

30.

Roncati M, Lucchese A, Carinci F (2013) Non-surgical treatment of peri-implantitis with the adjunctive use of an 810-nm diode laser. J Indian Soc Periodontol 17(6):812–815. https://doi.org/10.4103/0972-124X.124531CrossRefPubMedPubMedCentral

31.

Romanos GE, Gutknecht N, Dieter S, Schwarz F, Crespi R, Sculean A (2009) Laser wavelengths and oral implantology. Lasers Med Sci 24(6):961–970. https://doi.org/10.1007/s10103-009-0676-1CrossRefPubMed

32.

Schwarz F, Aoki A, Sculean A (2000) Becker J (2009) The impact of laser application on periodontal and peri-implant wound healing. Periodontol 51:79–108. https://doi.org/10.1111/j.1600-0757.2009.00301.xCrossRef

33.

Siefert SA, Sarkar R (2012) Matrix metalloproteinases in vascular physiology and disease. Vascular 20(4):210–216. https://doi.org/10.1258/vasc.2011.201202CrossRefPubMed

34.

Baker EA, Leaper DJ (2003) Profiles of matrix metalloproteinases and their tissue inhibitors in intraperitoneal drainage fluid: relationship to wound healing. Wound Repair Regen 11(4):268–274. https://doi.org/10.1046/j.1524-475x.2003.11406.xCrossRefPubMed

35.

Alpagot T, Suzara V, Bhattacharyya M (2006) The associations between gingival crevice fluid matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and periodontitis in human immunodeficiency virus-positive patients. J Periodontal Res 41(6):491–497. https://doi.org/10.1111/j.1600-0765.2006.00887.xCrossRefPubMed

36.

Ghighi M, Llorens A, Baroukh B, Chaussain C, Bouchard P, Gosset M (2018) Differences between inflammatory and catabolic mediators of peri-implantitis and periodontitis lesions following initial mechanical therapy: an exploratory study. J Periodontal Res 53(1):29–39. https://doi.org/10.1111/jre.12483CrossRefPubMed

37.

Wang HL, Garaicoa-Pazmino C, Collins A, Ong HS, Chudri R, Giannobile WV (2016) Protein biomarkers and microbial profiles in peri-implantitis. Clin Oral Implants Res 27(9):1129–1136. https://doi.org/10.1111/clr.12708CrossRefPubMed

38.

Tuter G, Kurtis B, Serdar M (2002) Effects of phase I periodontal treatment on gingival crevicular fluid levels of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1. J Periodontol 73(5):487–493. https://doi.org/10.1902/jop.2002.73.5.487CrossRefPubMed

39.

Ghassib I, Chen Z, Zhu J, Wang HL (2019) Use of IL-1 β, IL-6, TNF-α, and MMP-8 biomarkers to distinguish peri-implant diseases: a systematic review and meta-analysis. Clin Implant Dent Relat Res 21(1):190–207. https://doi.org/10.1111/cid.12694CrossRefPubMed

Titel: Erbium, chromium-doped: yttrium, scandium, gallium, garnet and diode lasers in the treatment of peri‐implantitis: clinical and biochemical outcomes in a randomized-controlled clinical trial
verfasst von: Nazli Zeynep Alpaslan Yayli
Ahmet Cemil Talmac
Serap Keskin Tunc
Damla Akbal
Dicle Altindal
Abdullah Seckin Ertugrul
Publikationsdatum: 12.10.2021
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 1/2022
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-021-03436-5

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2022

Photobiomodulation and diffusing optical fiber on spinal cord’s impact on nerve cells from normal spinal cord tissue in piglets

Antitumor effects of targeted killing of tumor-associated macrophages under photothermal conditions

Laser interstitial thermotherapy (LITT) for breast cancer: dosimetry optimization and numerical simulation

Mechanistic aspects of photobiomodulation therapy in the nervous system

A systematic review of randomised controlled trials investigating laser assisted drug delivery for the treatment of keloid and hypertrophic scars

The optimal settings of holmium YAG laser in treatment of pediatric urolithiasis