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Open Access 01.12.2016 | Erratum

Erratum to: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

verfasst von: J. R. Hens, I. Sinha, F. Perodin, T. Cooper, R. Sinha, J. Plummer, C. E. Perrone, D. Orentreich

Erschienen in: BMC Cancer | Ausgabe 1/2016

The online version of the original article can be found under doi:10.1186/s12885-016-2367-1.

The online version of the original article can be found at http://dx.doi.org/10.1186/s12885-016-2367-1.

Erratum

After publication of the original article [1], it was noticed that the uncorrected version of this article was published which contained a typographical error within Tables 1 and 2. Within Table 1 the value “11.4 ± 4 03” incorrectly read as “114 ± 4 03”. Within Table 2 the value “46.9 ± 17” incorrectly read as “46 9 ± 17”. These errors do not in any way effect the results, findings, interpretation, conclusions, or the scientific basis of the paper. The correct versions of Tables 1 and 2 can be found below, and have been corrected in the original article.

Table 1

Physiological parameters of mice on MR and CF diets. A 2-tailed t-test was conducted

	CF			MR
	Mean (g) SD	Mean (%) SD	N	Mean SD	Mean (%) SD	N
Body weight	26.6 ± 2.79		18	23.9 ± 2.3***		20
Liver	1.13 ± 0.15	4.35 ± 0.43	19	0.988 ± 0.13 **	4.15 ± 0.49	20
Spleen	0.102 ± 0.02	0.383 ± 0.07	19	0.104 ± 0.15	0.436 ± 0.59	20
MFP (both)	0.271 ± 0.06	1.01 ± 0.20	18	0.275 ± 0.10	1.13 ± 0.35	20
Kidney (both)	0.343 ± 0.04	1.33 ± 0.19	19	0.303 ± 0.05 **	1.27 ± 0.19	20
Muscle-left side	0.123 ± 0.02	0.475 ± 0.89	19	0.081 ± 0.03 ****	0.339 ± 0.15 **	20
Tumor-wt (mg)	20.2 ± 6.1 ^a	0.079 ± 0.30	15	11.4 ± 4 03 ^a ****	0.049 ± 0.02***	20

**** p ≤ 0.0001, *** p ≤ 0.001, ** p ≤ 0.01

^a tumor is in mg not g

Table 2

Plasma amino acid concentrations from mice on MR and CF diets. Levels of methionine, cysteine, and taurine in the plasma from mice on the MR diet are significantly lower than those on the control diet. The Kruskal-Wallis test was used to analyze the differences in amino acid concentration

	CF		MR
	Mean (nmol/mL) SD	N	Mean (nmol/mL) SD	N
Ala	398 ± 85	17	520 ± 122 ***	18
Arg	133 ± 29	17	117 ± 21	18
Asp	11.8 ± 4.9	16	10.3 ± 3.1	18
Cys	4.39 ± 2.4	13	2.22 ± 0.44 *	9
Gln	622 ± 89	17	812 ± 106****	18
Glu	106 ± 20	17	117 ± 19	18
His	88.8 ± 11	17	112 ± 20***	18
Ile	94.8 ± 32	17	108 ± 27	18
Leu	139 ± 47	17	180 ± 46**	18
Met	248 ± 125	17	46.9 ± 17****	18
Orn	62.7 ± 29	17	114 ± 41***	18
Phe	114 ± 42	17	132 ± 39	18
Pro	69.5 ± 8.6	17	82.4 ± 34	18
Ser	218 ± 34	17	339 ± 84****	18
Tau	226 ± 50	17	77.1 ± 35****	18
Thr	346 ± 94	17	383 ± 136	18
Tyr	89.5 ± 19	17	107 ± 28*	18
Trp	130 ± 29	17	128 ± 29	18

**** p ≤ 0.0001, *** p ≤ 0.001, ** p ≤ 0.01, * p ≤ 0.05

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Hens JR, Sinha I, Perodin F, Cooper T, Sinha R, Plummer J, et al. Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice. BMC Cancer. 2016;16:349. doi:10.1186/s12885-016-2367-1.CrossRefPubMedPubMedCentral

Titel: Erratum to: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice
verfasst von: J. R. Hens
I. Sinha
F. Perodin
T. Cooper
R. Sinha
J. Plummer
C. E. Perrone
D. Orentreich
Publikationsdatum: 01.12.2016
Verlag: BioMed Central
Erschienen in: BMC Cancer / Ausgabe 1/2016
Elektronische ISSN: 1471-2407
DOI: https://doi.org/10.1186/s12885-016-2404-0

Springer Medizin

Erratum to: Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice

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