Ausgabe 4/2022
Inhalt (13 Artikel)
Time for Isoniazid Pharmacogenomic-Guided Therapy of Tuberculosis Based on NAT2 Acetylation Profiles in India
Nikhat Khan, Aparup Das
Systematic Review and Pharmacokinetic Meta-analysis of Doxorubicin Exposure in Transcatheter Arterial Chemoembolization and Doxorubicin-Eluted Beads Chemoembolization for Treatment of Unresectable Hepatocellular Carcinoma
Mohammadreza Zarisfi, Arta Kasaeian, Anna Wen, Eleni Liapi
Characterization of Correction Factors to Enable Assessment of Clinical Risk from In Vitro CYP3A4 Induction Data and Basic Drug-Drug Interaction Models
Diane Ramsden, Cody L. Fullenwider
A Mechanistic Absorption and Disposition Model of Ritonavir to Predict Exposure and Drug–Drug Interaction Potential of CYP3A4/5 and CYP2D6 Substrates
Sumit Arora, Amita Pansari, Peter J. Kilford, Masoud Jamei, David B. Turner, Iain Gardner
Population Pharmacokinetic Modelling of Acetaminophen and Ibuprofen: the Influence of Body Composition, Formulation and Feeding in Healthy Adult Volunteers
James D. Morse, Ioana Stanescu, Hartley C. Atkinson, Brian J. Anderson
Safety, Tolerability, and Pharmacokinetic Study of 101BHG-D01 Nasal Spray, a Novel Long-Acting and Selective Cholinergic M Receptor Antagonist, in Healthy Chinese Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Escalation, First-In-Human Study
Nan-nan Chu, Kai Huang, Lin-Ling Que, Ying Ding, Xiang-hong Gu, Lin Zhang, Jia-kun Wang, Xiao-ping Chen, Zhan-guo Sun, Qing He
A Population Pharmacokinetic Model of Whole-Blood and Intracellular Tacrolimus in Kidney Transplant Recipients
Linda G. Franken, Marith I. Francke, Louise M. Andrews, Ron H. N. van Schaik, Yi Li, Lucia E. A. de Wit, Carla C. Baan, Dennis A. Hesselink, Brenda C. M de Winter
Integrated Population Pharmacokinetic Analysis of Ustekinumab Across Multiple Immune-Mediated Inflammatory Disease Populations and Healthy Subjects
Jie Shao, Zhenhua Xu, Yan Xu
Results From Phase I Studies Investigating the Dose Linearity of Finerenone Tablets and the Influence of Food or pH-Modifying Comedications on its Pharmacokinetics in Healthy Male Volunteers
Roland Heinig, Johannes Nagelschmitz, Stephanie Loewen
Therapeutic Drug Monitoring and Prolonged Infusions of Ceftolozane/Tazobactam for MDR/XDR Pseudomonas aeruginosa Infections: An Observational Study
María Eugenia Navarrete-Rouco, Sònia Luque, Luisa Sorlí, Adela Benítez-Cano, Jason A. Roberts, Santiago Grau
Bioavailability Study of a Transdermal Patch Formulation of Rivastigmine Compared with Exelon in Healthy Subjects
Adelaida Morte, Anna Vaqué, Marc Iniesta, Barbara Schug, Cornelius Koch, Rafael De la Torre, Bjoern Schurad
An Open Label, Phase 1, Randomized, Seven-treatment, Seven-period, Crossover Study to Assess the Relative Bioavailability, pH Effect, Food Effect, and Dose Proportionality of CC-292, a Potent and Orally Available Bruton’s Tyrosine Kinase Inhibitor
Yiming Cheng, Liangang Liu, Yongjun Xue, Simon Zhou, Yan Li
Pharmacokinetic and Pharmacodynamic Properties of Indole-3-carbinol in Experimental Focal Ischemic Injury
Kakarla Ramakrishna, Shreyans K. Jain, Sairam Krishnamurthy