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Graefe's Archive for Clinical and Experimental Ophthalmology

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12.12.2018 | Retinal Disorders

Evaluation of retinal vasculature before and after treatment of children with obstructive sleep apnea-hypopnea syndrome by optical coherence tomography angiography

verfasst von: Haiyun Ye, Ce Zheng, Xiaoping Lan, Limin Zhao, Tong Qiao, Xiaoyan Li, Yidan Zhang

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 3/2019

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Abstract

Purpose

To evaluate the effect of adenoidectomy on the brains of children with obstructive sleep apnea-hypopnea syndrome (OSAS) through observation of the alteration of retinal perfusion by optical coherence tomography angiography (OCTA).

Methods

Sixty-two children with OSAS (124 eyes; 5.94 ± 1.64 years old; 53.2% boys) were enrolled in this study. Their retinal vascular network density indices, including vascular diameter (VD), vascular area density (VAD), vessel skeleton density (VSD), vessel perimeter index (VPI) on the macular superficial/deep capillary plexus (SCP/DCP), and the size of the foveal avascular zone (FAZ) were analyzed by OCTA before treatment and at 1 month after the adenoidectomy.

Results

After the adenoidectomy, the values of VD, VAD, VSD, and VPI in the SCP/DCP of the parafovea were significantly increased (p < 0.01). The FAZ was significantly diminished in the SCP (t = 4.50, p < 0.05) and increased in the DCP (t = − 4.43, p < 0.05). The peripapillary indices in the SCP/DCP were not significantly changed (p > 0.05).

Conclusion

By improvement of hypoxia, the response of the parafoveal vessels was more sensitive than that of the peripapillary region in children with OSAS. Therefore, OCTA may be an ideal method to evaluate the changes of the retinal vascular system, which could be an effective parameter for the early evaluation of adenoidectomy on cases of pediatric OSAS.

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Titel: Evaluation of retinal vasculature before and after treatment of children with obstructive sleep apnea-hypopnea syndrome by optical coherence tomography angiography
verfasst von: Haiyun Ye
Ce Zheng
Xiaoping Lan
Limin Zhao
Tong Qiao
Xiaoyan Li
Yidan Zhang
Publikationsdatum: 12.12.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 3/2019
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-018-04207-9

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