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Erschienen in: Aesthetic Plastic Surgery 5/2009

01.09.2009 | Original Article

Evaluation of the Risk of Systemic Fat Mobilization and Fat Embolus Following Liposuction with Dry and Tumescent Technique: An Experimental Study on Rats

verfasst von: Dilek Şenen, D. Atakul, G. Erten, B. Erdoğan, N. Lortlar

Erschienen in: Aesthetic Plastic Surgery | Ausgabe 5/2009

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Abstract

Background

Clinical studies have revealed that liposuction causes systemic fat mobilization. However, the degree of the risk it causes is not clear. In this study we investigated the risk of systemic fat mobilization and fat embolus in rats following liposuction using dry and tumescent techniques.

Methods

At the end of the procedures, the rats were sacrificed and specimens were obtained from the lungs, kidneys, liver, brain, and skin. Histological examinations of the specimens were carried out. Liposuction was not performed in the control group (n = 8), but blood and tissue specimens for histological examinations were obtained.

Results

We found signs of fat embolus in both blood specimens and histological examinations of tissue samples in the study groups. However, the results of the examinations were normal in the control group. Although there were no fat particles in the blood before liposuction, blood specimens obtained following the procedures and in the long-term had fat particles.
Literatur
1.
Zurück zum Zitat Kenkel JM, Brown SA, Love EJ, Waddle JP, Krueger JE, Noble D, Robinson JB Jr, Rohrich RJ (2004) Hemodynamics, electrolytes and organ histology of larger-volume liposuction in a porcine model. Plast Reconstr Surg 113(5):1391–1399PubMedCrossRef Kenkel JM, Brown SA, Love EJ, Waddle JP, Krueger JE, Noble D, Robinson JB Jr, Rohrich RJ (2004) Hemodynamics, electrolytes and organ histology of larger-volume liposuction in a porcine model. Plast Reconstr Surg 113(5):1391–1399PubMedCrossRef
2.
Zurück zum Zitat Rohrich R (2000) The increased popularity of cosmetic surgery procedures: A look at statistics in plastic surgery. Plast Reconstr Surg 106:1363–1365PubMedCrossRef Rohrich R (2000) The increased popularity of cosmetic surgery procedures: A look at statistics in plastic surgery. Plast Reconstr Surg 106:1363–1365PubMedCrossRef
3.
Zurück zum Zitat Rao RB, Ely SF, Hoffman RS (1999) Deaths related to liposuction. N Engl J Med 340:1471–1475PubMedCrossRef Rao RB, Ely SF, Hoffman RS (1999) Deaths related to liposuction. N Engl J Med 340:1471–1475PubMedCrossRef
4.
Zurück zum Zitat Rohrich R, Beran SJ, Fodor PB (1997) The role of subcutaneous infiltration in suction-assisted lipoplasty: A review. Plast Reconstr Surg 99:514–519PubMedCrossRef Rohrich R, Beran SJ, Fodor PB (1997) The role of subcutaneous infiltration in suction-assisted lipoplasty: A review. Plast Reconstr Surg 99:514–519PubMedCrossRef
6.
Zurück zum Zitat Samdal F (1995) Effect of syringe-assisted liposuction on activation of cascade systems and circulating cells when using superwet or tumescent technique. Ann Plast Surg 35(3):242–248PubMedCrossRef Samdal F (1995) Effect of syringe-assisted liposuction on activation of cascade systems and circulating cells when using superwet or tumescent technique. Ann Plast Surg 35(3):242–248PubMedCrossRef
7.
Zurück zum Zitat Hunstad, Withers (1984) Fat embolism syndrome. West J Med 141:501–505 Hunstad, Withers (1984) Fat embolism syndrome. West J Med 141:501–505
8.
Zurück zum Zitat Teimourian B, Rogers WB (1989) A national survey of complications associated with suction lipectomy. A comparative study. Plast Reconstr Surg 84:628–631PubMedCrossRef Teimourian B, Rogers WB (1989) A national survey of complications associated with suction lipectomy. A comparative study. Plast Reconstr Surg 84:628–631PubMedCrossRef
9.
Zurück zum Zitat Levy D (1990) The fat embolism syndrome. A review. Clin Orthop Relat Res (261):281–286 Levy D (1990) The fat embolism syndrome. A review. Clin Orthop Relat Res (261):281–286
10.
Zurück zum Zitat Fourme T, Vieillard-Baron A, Loubieres Y, Julie C, Page B, Jardin F (1998) Early fat embolism after liposuction. Anesthesiology 89:782–784PubMedCrossRef Fourme T, Vieillard-Baron A, Loubieres Y, Julie C, Page B, Jardin F (1998) Early fat embolism after liposuction. Anesthesiology 89:782–784PubMedCrossRef
11.
Zurück zum Zitat Fraser RS, Pare PD (1999) Emboli of extravascular tissue and foreign material. In: Fraser RS, Pare PD (eds) Synopsis of diseases of the chest, 4th edn. W.B. Saunders, Philadelphia, pp 1845–1876 Fraser RS, Pare PD (1999) Emboli of extravascular tissue and foreign material. In: Fraser RS, Pare PD (eds) Synopsis of diseases of the chest, 4th edn. W.B. Saunders, Philadelphia, pp 1845–1876
12.
Zurück zum Zitat Grazer FM, de Jong RH (2000) Fatal outcomes from liposuction: Census survey of cosmetic surgeons. Plast Reconstr Surg 105(1):436–446PubMedCrossRef Grazer FM, de Jong RH (2000) Fatal outcomes from liposuction: Census survey of cosmetic surgeons. Plast Reconstr Surg 105(1):436–446PubMedCrossRef
13.
Zurück zum Zitat Gilliland MD, Coates N (1997) Tumescent liposuction complicated by pulmonary edema. Plast Reconstr Surg 99:215–219PubMedCrossRef Gilliland MD, Coates N (1997) Tumescent liposuction complicated by pulmonary edema. Plast Reconstr Surg 99:215–219PubMedCrossRef
14.
Zurück zum Zitat Gorney M (2001) Sucking fat: An 18-year statistical and personal retrospective. Plast Reconstr Surg 107:608–613PubMedCrossRef Gorney M (2001) Sucking fat: An 18-year statistical and personal retrospective. Plast Reconstr Surg 107:608–613PubMedCrossRef
15.
Zurück zum Zitat El-Ali KM, Gourlay T (2006) Assessment of the risk of systemic fat mobilization and fat embolism as a consequence of liposuction: ex vivo study. Plast Reconstr Surg 117(7):2269–2276PubMedCrossRef El-Ali KM, Gourlay T (2006) Assessment of the risk of systemic fat mobilization and fat embolism as a consequence of liposuction: ex vivo study. Plast Reconstr Surg 117(7):2269–2276PubMedCrossRef
16.
Zurück zum Zitat Kiernan JA (1981) Histological and histochemical methods, 1st edn. Pergamon Press, Oxford, pp 201–230 Kiernan JA (1981) Histological and histochemical methods, 1st edn. Pergamon Press, Oxford, pp 201–230
17.
Zurück zum Zitat King MB, Harmon KR (1994) Unusual forms of pulmonary embolism. Clin Chest Med 15(3):561–580PubMed King MB, Harmon KR (1994) Unusual forms of pulmonary embolism. Clin Chest Med 15(3):561–580PubMed
18.
Zurück zum Zitat Laub DR Jr, Laub DR (1990) Fat embolism after liposuction: a case report and review of the literature. Ann Plast Surg 25:48–52PubMedCrossRef Laub DR Jr, Laub DR (1990) Fat embolism after liposuction: a case report and review of the literature. Ann Plast Surg 25:48–52PubMedCrossRef
19.
Zurück zum Zitat Platt MS, Kohler LJ, Ruiz R, Cohle SD, Ravichandran P (2002) Deaths associated with liposuction: case reports and review of the literature. J Forensic Sci 47:205–207PubMed Platt MS, Kohler LJ, Ruiz R, Cohle SD, Ravichandran P (2002) Deaths associated with liposuction: case reports and review of the literature. J Forensic Sci 47:205–207PubMed
20.
Zurück zum Zitat Abbes M, Bourgeon Y (1989) Fat embolism after dermalipectomy and liposuction [letter]. Plast Reconstr Surg 84:546–547PubMedCrossRef Abbes M, Bourgeon Y (1989) Fat embolism after dermalipectomy and liposuction [letter]. Plast Reconstr Surg 84:546–547PubMedCrossRef
21.
Zurück zum Zitat Christman KD (1986) Death following suction lipectomy and abdominoplasty. Plast Reconstr Surg 78:428PubMedCrossRef Christman KD (1986) Death following suction lipectomy and abdominoplasty. Plast Reconstr Surg 78:428PubMedCrossRef
22.
Zurück zum Zitat de Jong RH, Grazer FM (2001) Perioperative management of cosmetic liposuction. Plast Reconstr Surg 107:1039–1044PubMedCrossRef de Jong RH, Grazer FM (2001) Perioperative management of cosmetic liposuction. Plast Reconstr Surg 107:1039–1044PubMedCrossRef
24.
Zurück zum Zitat Foroozan R, Varon J (2004) Bilateral anterior ischemic optic neuropathy after liposuction. J Neuroophthalmol 24(3):211–213PubMed Foroozan R, Varon J (2004) Bilateral anterior ischemic optic neuropathy after liposuction. J Neuroophthalmol 24(3):211–213PubMed
25.
Zurück zum Zitat Ballaux PK, Courlay T, Ratnatunga AH, Taylor KM (1999) A literature review of cardiopulmonary bypass models for rats. Perfusion 14:411PubMed Ballaux PK, Courlay T, Ratnatunga AH, Taylor KM (1999) A literature review of cardiopulmonary bypass models for rats. Perfusion 14:411PubMed
Metadaten
Titel
Evaluation of the Risk of Systemic Fat Mobilization and Fat Embolus Following Liposuction with Dry and Tumescent Technique: An Experimental Study on Rats
verfasst von
Dilek Şenen
D. Atakul
G. Erten
B. Erdoğan
N. Lortlar
Publikationsdatum
01.09.2009
Verlag
Springer-Verlag
Erschienen in
Aesthetic Plastic Surgery / Ausgabe 5/2009
Print ISSN: 0364-216X
Elektronische ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-009-9396-y

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