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Erschienen in: Forensic Science, Medicine and Pathology 4/2020

11.05.2020 | Images in Forensics

Fatal Epstein-Barr virus infection in an immunocompetent host: a postmortem diagnosis

verfasst von: Aniello Maiese, Raffaele La Russa, Giovanna Passaro, Paola Santoro, Alessandra De Matteis, Vittorio Fineschi

Erschienen in: Forensic Science, Medicine and Pathology | Ausgabe 4/2020

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Abstract

Meningoencephalitis is the most common neurological complication related to Epstein-Barr virus (EBV), and in immunocompetent adults, it is most commonly self-limited. We describe a case of fatal EBV infection characterized by meningoencephalitis, foci of myocarditis and interstitial nephritis in an immunocompetent 74-year-old man. The postmortem diagnosis was made based on the presence of EBV DNA in the cerebrospinal fluid and by immunohistochemical assay that showed spots of intracellular positivity to anti-EBV antibody in brain tissue.
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Metadaten
Titel
Fatal Epstein-Barr virus infection in an immunocompetent host: a postmortem diagnosis
verfasst von
Aniello Maiese
Raffaele La Russa
Giovanna Passaro
Paola Santoro
Alessandra De Matteis
Vittorio Fineschi
Publikationsdatum
11.05.2020
Verlag
Springer US
Erschienen in
Forensic Science, Medicine and Pathology / Ausgabe 4/2020
Print ISSN: 1547-769X
Elektronische ISSN: 1556-2891
DOI
https://doi.org/10.1007/s12024-020-00254-z

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