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Erschienen in:

01.04.2021 | Original Article

Feasibility of computed tomography-based assessment of skeletal muscle mass in hemodialysis patients

verfasst von: Tomoaki Takata, Aki Motoe, Katsumi Tanida, Sosuke Taniguchi, Ayami Ida, Kentaro Yamada, Shintaro Hamada, Masaya Ogawa, Marie Yamamoto, Yukari Mae, Takuji Iyama, Munehiro Taniguchi, Akihisa Nakaoka, Hajime Isomoto

Erschienen in: Journal of Nephrology | Ausgabe 2/2021

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Abstract

Background

Sarcopenia is a major health issue especially in patients on maintenance hemodialysis. Low skeletal muscle mass is included in the diagnostic criteria for sarcopenia. The skeletal muscle mass is usually evaluated by modalities such as bioimpedance analysis (BIA) or dual-energy X-ray absorptiometry, however the assessment of skeletal muscle mass using computed tomography (CT) images has not been established. The purpose of the study was to investigate the feasibility of the assessment of skeletal muscle mass using CT images in hemodialysis patients.

Methods

Skeletal muscle mass index (SMI) was measured by BIA and psoas muscle index (PMI) was measured by cross-sectional CT images in 131 patients. The relationship between SMI and PMI and the diagnostic ability of PMI for low muscle mass were evaluated. Furthermore, the patients were followed up and long-term survival in patients with low and high PMI were compared.

Results

PMI measured at the L3 vertebral level was strongly correlated with SMI (r = 0.597, p < 0.001). Age, sex, and SMI were the influencing factors for PMI. Patients with low PMI showed higher incidence rates of mortality during the follow up.

Conclusions

PMI assessed by CT image can be an alternative to BIA in patients on hemodialysis.

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Titel: Feasibility of computed tomography-based assessment of skeletal muscle mass in hemodialysis patients
verfasst von: Tomoaki Takata
Aki Motoe
Katsumi Tanida
Sosuke Taniguchi
Ayami Ida
Kentaro Yamada
Shintaro Hamada
Masaya Ogawa
Marie Yamamoto
Yukari Mae
Takuji Iyama
Munehiro Taniguchi
Akihisa Nakaoka
Hajime Isomoto
Publikationsdatum: 01.04.2021
Verlag: Springer International Publishing
Erschienen in: Journal of Nephrology / Ausgabe 2/2021
Print ISSN: 1121-8428
Elektronische ISSN: 1724-6059
DOI: https://doi.org/10.1007/s40620-020-00871-5

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Feasibility of computed tomography-based assessment of skeletal muscle mass in hemodialysis patients