Skip to main content

2013 | OriginalPaper | Buchkapitel

17. Fetale Magnetresonanztomografie

verfasst von : Chressen Catharina Remus, Dr. med., Ruxandra Milos, Dr. med., Ulrike Wedegärtner, Prof. Dr. med.

Erschienen in: Ultraschalldiagnostik in Geburtshilfe und Gynäkologie

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Die fetale Magnetresonanztomografie (MRT) hat in den letzten Jahren erheblich an klinischer Bedeutung gewonnen (Glenn u. Barkovich 2006, Levine et al. 2003a, Levine et al. 2002).
Literatur
Zurück zum Zitat Achiron R, Schimmel M, Achiron A, Mashiach S (1993) Fetal mild idiopathic lateral ventriculomegaly: is there a correlation with fetal trisomy. Ultrasound Obstet Gynecol 3(2):89–92CrossRefPubMed Achiron R, Schimmel M, Achiron A, Mashiach S (1993) Fetal mild idiopathic lateral ventriculomegaly: is there a correlation with fetal trisomy. Ultrasound Obstet Gynecol 3(2):89–92CrossRefPubMed
Zurück zum Zitat Aitken LA, Lindan CE, Sidney S, Gupta N, Barkovich AJ, Sorel M, Wu YW (2009) Chiari type I malformation in a pediatric population. Pediatr Neurol 40(6):449–454CrossRefPubMedPubMedCentral Aitken LA, Lindan CE, Sidney S, Gupta N, Barkovich AJ, Sorel M, Wu YW (2009) Chiari type I malformation in a pediatric population. Pediatr Neurol 40(6):449–454CrossRefPubMedPubMedCentral
Zurück zum Zitat Alamo L, Laswad T, Schnyder P, Meuli R, Vial Y, Osterheld M-C, Gudinchet F (2010) Fetal MRI as complement to US in the diagnosis and characterization of anomalies of the genito-urinary tract. Eur J Radiol 76(2):258–264CrossRefPubMed Alamo L, Laswad T, Schnyder P, Meuli R, Vial Y, Osterheld M-C, Gudinchet F (2010) Fetal MRI as complement to US in the diagnosis and characterization of anomalies of the genito-urinary tract. Eur J Radiol 76(2):258–264CrossRefPubMed
Zurück zum Zitat Al-Assiri A, Wiseman N, Bunge M (2005) Prenatal diagnosis of intrathoracic stomach (gastric herniation). J Pediatr Surg 40(2):E15–E17CrossRefPubMed Al-Assiri A, Wiseman N, Bunge M (2005) Prenatal diagnosis of intrathoracic stomach (gastric herniation). J Pediatr Surg 40(2):E15–E17CrossRefPubMed
Zurück zum Zitat Al-Hussein HA, Graham EM, Tekes A, Huisman TAGM (2011) Pre- and postnatal imaging of a congenital hepatoblastoma. Fetal Diagn Ther 30(2):157–159CrossRefPubMed Al-Hussein HA, Graham EM, Tekes A, Huisman TAGM (2011) Pre- and postnatal imaging of a congenital hepatoblastoma. Fetal Diagn Ther 30(2):157–159CrossRefPubMed
Zurück zum Zitat Ando K, Ishikura R, Ogawa M, Shakudo M, Takada Y, Minagawa K, Tanaka H et al (2007) MRI tight posterior fossa sign for prenatal diagnosis of Chiari type II malformation. Neuroradiology 49(12):1033–1039CrossRefPubMed Ando K, Ishikura R, Ogawa M, Shakudo M, Takada Y, Minagawa K, Tanaka H et al (2007) MRI tight posterior fossa sign for prenatal diagnosis of Chiari type II malformation. Neuroradiology 49(12):1033–1039CrossRefPubMed
Zurück zum Zitat Bahado-Singh R, Oz U, Mari G, Jones D, Paidas M, Onderoglu L (1998) Fetal splenic size in anemia due to Rh-alloimmunization. Obstet Gynecol 92(5):828–832PubMed Bahado-Singh R, Oz U, Mari G, Jones D, Paidas M, Onderoglu L (1998) Fetal splenic size in anemia due to Rh-alloimmunization. Obstet Gynecol 92(5):828–832PubMed
Zurück zum Zitat Baker PN, Johnson IR, Harvey PR, Gowland PA, Mansfield P (1994) A three-year follow-up of children imaged in utero with echo-planar magnetic resonance. Am J Obstet Gynecol 170(1 Pt 1):32–33CrossRefPubMed Baker PN, Johnson IR, Harvey PR, Gowland PA, Mansfield P (1994) A three-year follow-up of children imaged in utero with echo-planar magnetic resonance. Am J Obstet Gynecol 170(1 Pt 1):32–33CrossRefPubMed
Zurück zum Zitat Barkovich AJ, Rowley H, Bollen A (1995) Correlation of prenatal events with the development of polymicrogyria. AJNR Am J Neuroradiol 16(4 Suppl):822–827PubMedPubMedCentral Barkovich AJ, Rowley H, Bollen A (1995) Correlation of prenatal events with the development of polymicrogyria. AJNR Am J Neuroradiol 16(4 Suppl):822–827PubMedPubMedCentral
Zurück zum Zitat Basser PJ, Pajevic S, Pierpaoli C, Duda J, Aldroubi A (2000) In vivo fiber tractography using DT-MRI data. Magn Reson Med 44(4):625–632CrossRefPubMed Basser PJ, Pajevic S, Pierpaoli C, Duda J, Aldroubi A (2000) In vivo fiber tractography using DT-MRI data. Magn Reson Med 44(4):625–632CrossRefPubMed
Zurück zum Zitat Biran-Gol Y, Malinger G, Cohen H, Davidovitch M, Lev D, Lerman-Sagie T, Schweiger A (2010) Developmental outcome of isolated fetal macrocephaly. Ultrasound Obstet Gynecol 36(2):147–153CrossRefPubMed Biran-Gol Y, Malinger G, Cohen H, Davidovitch M, Lev D, Lerman-Sagie T, Schweiger A (2010) Developmental outcome of isolated fetal macrocephaly. Ultrasound Obstet Gynecol 36(2):147–153CrossRefPubMed
Zurück zum Zitat Boddaert N, Klein O, Ferguson N, Sonigo P, Baraton J, Hertz-Pannier L, Parisot D et al (2003) Intellectual prognosis of the Dandy-Walker malformation in children: the importance of vermian lobulation. Neuroradiology 45(5):320–324CrossRefPubMed Boddaert N, Klein O, Ferguson N, Sonigo P, Baraton J, Hertz-Pannier L, Parisot D et al (2003) Intellectual prognosis of the Dandy-Walker malformation in children: the importance of vermian lobulation. Neuroradiology 45(5):320–324CrossRefPubMed
Zurück zum Zitat Braillon A (2010) Practice parameter: evaluation of the child with microcephaly (an evidence-based review): report of the quality standards subcommittee of the American Academy Of Neurology and the Practice Committee Of The Child Neurology Society. Neurology 74(13):1079–1080 (author reply 1080)CrossRefPubMed Braillon A (2010) Practice parameter: evaluation of the child with microcephaly (an evidence-based review): report of the quality standards subcommittee of the American Academy Of Neurology and the Practice Committee Of The Child Neurology Society. Neurology 74(13):1079–1080 (author reply 1080)CrossRefPubMed
Zurück zum Zitat Breeze ACG, Alexander PMA, Murdoch EM, Missfelder-Lobos HH, Hackett GA, Lees CC (2007) Obstetric and neonatal outcomes in severe fetal ventriculomegaly. Prenat Diagn 27(2):124–129CrossRefPubMed Breeze ACG, Alexander PMA, Murdoch EM, Missfelder-Lobos HH, Hackett GA, Lees CC (2007) Obstetric and neonatal outcomes in severe fetal ventriculomegaly. Prenat Diagn 27(2):124–129CrossRefPubMed
Zurück zum Zitat Büsing KA, Kilian AK, Schaible T, Debus A, Weiss C, Neff KW (2008) Reliability and validity of MR image lung volume measurement in fetuses with congenital diaphragmatic hernia and in vitro lung models. Radiology 246(2):553–561CrossRefPubMed Büsing KA, Kilian AK, Schaible T, Debus A, Weiss C, Neff KW (2008) Reliability and validity of MR image lung volume measurement in fetuses with congenital diaphragmatic hernia and in vitro lung models. Radiology 246(2):553–561CrossRefPubMed
Zurück zum Zitat Carcopino X, Chaumoitre K, Shojai R, Panuel M, Boubli L, D’Ercole C (2006) Use of fetal magnetic resonance imaging in differentiating ileal atresia from meconium ileus. Ultrasound Obstet Gynecol 28(7):976–977CrossRefPubMed Carcopino X, Chaumoitre K, Shojai R, Panuel M, Boubli L, D’Ercole C (2006) Use of fetal magnetic resonance imaging in differentiating ileal atresia from meconium ileus. Ultrasound Obstet Gynecol 28(7):976–977CrossRefPubMed
Zurück zum Zitat Cardoza JD, Goldstein RB, Filly RA (1988) Exclusion of fetal ventriculomegaly with a single measurement: the width of the lateral ventricular atrium. Radiology 169(3):711–714CrossRefPubMed Cardoza JD, Goldstein RB, Filly RA (1988) Exclusion of fetal ventriculomegaly with a single measurement: the width of the lateral ventricular atrium. Radiology 169(3):711–714CrossRefPubMed
Zurück zum Zitat Carroll SG, Porter H, Abdel-Fattah S, Kyle PM, Soothill PW (2000) Correlation of prenatal ultrasound diagnosis and pathologic findings in fetal brain abnormalities. Ultrasound Obstet Gynecol 16(2):149–153CrossRefPubMed Carroll SG, Porter H, Abdel-Fattah S, Kyle PM, Soothill PW (2000) Correlation of prenatal ultrasound diagnosis and pathologic findings in fetal brain abnormalities. Ultrasound Obstet Gynecol 16(2):149–153CrossRefPubMed
Zurück zum Zitat Cassart M, Avni FE, Guibaud L, Molho M, D’Haene N, Paupe A (2011) Fetal liver iron overload: the role of MR imaging. Eur Radiol 21(2):295–300CrossRefPubMed Cassart M, Avni FE, Guibaud L, Molho M, D’Haene N, Paupe A (2011) Fetal liver iron overload: the role of MR imaging. Eur Radiol 21(2):295–300CrossRefPubMed
Zurück zum Zitat Cassart M, Massez A, Metens T, Rypens F, Lambot MA, Hall M, Avni FE (2004) Complementary Role of MRI After Sonography in Assessing Bilateral Urinary Tract Anomalies in the Fetus. AJR Am J Roentgenol 182(3):689–695CrossRefPubMed Cassart M, Massez A, Metens T, Rypens F, Lambot MA, Hall M, Avni FE (2004) Complementary Role of MRI After Sonography in Assessing Bilateral Urinary Tract Anomalies in the Fetus. AJR Am J Roentgenol 182(3):689–695CrossRefPubMed
Zurück zum Zitat Chaoui R, Zodan-Marin T, Wisser J (2002) Marked splenomegaly in fetal cytomegalovirus infection: detection supported by three-dimensional power Doppler ultrasound. Ultrasound Obstet Gynecol 20(3):299–302CrossRefPubMed Chaoui R, Zodan-Marin T, Wisser J (2002) Marked splenomegaly in fetal cytomegalovirus infection: detection supported by three-dimensional power Doppler ultrasound. Ultrasound Obstet Gynecol 20(3):299–302CrossRefPubMed
Zurück zum Zitat Chaumoitre K, Colavolpe N, Shojai R, Sarran A, Ercole DC, Panuel M (2007) Diffusion-weighted magnetic resonance imaging with apparent diffusion coefficient (ADC) determination in normal and pathological fetal kidneys. Ultrasound Obstet Gynecol 29(1):22–31CrossRefPubMed Chaumoitre K, Colavolpe N, Shojai R, Sarran A, Ercole DC, Panuel M (2007) Diffusion-weighted magnetic resonance imaging with apparent diffusion coefficient (ADC) determination in normal and pathological fetal kidneys. Ultrasound Obstet Gynecol 29(1):22–31CrossRefPubMed
Zurück zum Zitat deVries PA (1980) The pathogenesis of gastroschisis and omphalocele. J Pediatr Surg 15(3):245–251CrossRefPubMed deVries PA (1980) The pathogenesis of gastroschisis and omphalocele. J Pediatr Surg 15(3):245–251CrossRefPubMed
Zurück zum Zitat Dobyns WB, Pagon RA, Armstrong D, Curry CJ, Holmes LB, Grix A, Greenberg F et al (1989) Diagnostic criteria for Walker-Warburg syndrome. Am J Med Genet 32(2):195–210CrossRefPubMed Dobyns WB, Pagon RA, Armstrong D, Curry CJ, Holmes LB, Grix A, Greenberg F et al (1989) Diagnostic criteria for Walker-Warburg syndrome. Am J Med Genet 32(2):195–210CrossRefPubMed
Zurück zum Zitat Dolk H (1991) The predictive value of microcephaly during the first year of life for mental retardation at seven years. Dev Med Child Neurol 33(11):974–983CrossRefPubMed Dolk H (1991) The predictive value of microcephaly during the first year of life for mental retardation at seven years. Dev Med Child Neurol 33(11):974–983CrossRefPubMed
Zurück zum Zitat Drugan A, Weissman A, Evans MI (2001) Screening for neural tube defects. Clin Perinatol 28(2):279–287 (vii)CrossRefPubMed Drugan A, Weissman A, Evans MI (2001) Screening for neural tube defects. Clin Perinatol 28(2):279–287 (vii)CrossRefPubMed
Zurück zum Zitat Dubois J, Dehaene-Lambertz G, Perrin M, Mangin JF, Le Bihan D, Duchesnay E, Cointepas Y et al (2008) Asynchrony of the early maturation of white matter bundles in healthy infants: quantitative landmarks revealed noninvasively by diffusion tensor imaging. Hum Brain Mapp 29(1):14–27CrossRefPubMed Dubois J, Dehaene-Lambertz G, Perrin M, Mangin JF, Le Bihan D, Duchesnay E, Cointepas Y et al (2008) Asynchrony of the early maturation of white matter bundles in healthy infants: quantitative landmarks revealed noninvasively by diffusion tensor imaging. Hum Brain Mapp 29(1):14–27CrossRefPubMed
Zurück zum Zitat Dubourg C, David V, Gropman A, Mercier S, Muenke M, Odent S, Pineda-Alvarez DE, Roessler E (2010) Clinical utility gene card for: Holoprosencephaly. Eur J Hum Genet 19(1):121–121PubMedCentral Dubourg C, David V, Gropman A, Mercier S, Muenke M, Odent S, Pineda-Alvarez DE, Roessler E (2010) Clinical utility gene card for: Holoprosencephaly. Eur J Hum Genet 19(1):121–121PubMedCentral
Zurück zum Zitat Durfee SM, Kim FM, Benson CB (2001) Postnatal outcome of fetuses with the prenatal diagnosis of asymmetric hydrocephalus. J Ultrasound Med 20(3):263–268CrossRefPubMed Durfee SM, Kim FM, Benson CB (2001) Postnatal outcome of fetuses with the prenatal diagnosis of asymmetric hydrocephalus. J Ultrasound Med 20(3):263–268CrossRefPubMed
Zurück zum Zitat Ecker JL, Shipp TD, Bromley B, Benacerraf B (2000) The sonographic diagnosis of Dandy-Walker and Dandy-Walker variant: associated findings and outcomes. Prenat Diagn 20(4):328–332CrossRefPubMed Ecker JL, Shipp TD, Bromley B, Benacerraf B (2000) The sonographic diagnosis of Dandy-Walker and Dandy-Walker variant: associated findings and outcomes. Prenat Diagn 20(4):328–332CrossRefPubMed
Zurück zum Zitat Edwards MJ (2006) Review: Hyperthermia and fever during pregnancy. Birth Defects Res A Clin Mol Teratol 76(7):507–516CrossRefPubMed Edwards MJ (2006) Review: Hyperthermia and fever during pregnancy. Birth Defects Res A Clin Mol Teratol 76(7):507–516CrossRefPubMed
Zurück zum Zitat Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R, Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL (2009) Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopias. Hum Mol Genet 18(3):497–516CrossRefPubMed Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R, Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL (2009) Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopias. Hum Mol Genet 18(3):497–516CrossRefPubMed
Zurück zum Zitat Fernández-Mayoralas DM, Fernández-Jaén A, Jiménez-De-la-Peña M, Recio-Rodríguez M, Muñoz-Jareño N, Arroyo-González R (2010) Schizencephaly: pre- and postnatal magnetic resonance imaging. J Child Neurol 25(8):1020–1023CrossRefPubMed Fernández-Mayoralas DM, Fernández-Jaén A, Jiménez-De-la-Peña M, Recio-Rodríguez M, Muñoz-Jareño N, Arroyo-González R (2010) Schizencephaly: pre- and postnatal magnetic resonance imaging. J Child Neurol 25(8):1020–1023CrossRefPubMed
Zurück zum Zitat Forzano F, Mansour S, Ierullo A, Homfray T, Thilaganathan B (2007) Posterior fossa malformation in fetuses: a report of 56 further cases and a review of the literature. Prenat Diagn 27(6):495–501CrossRefPubMed Forzano F, Mansour S, Ierullo A, Homfray T, Thilaganathan B (2007) Posterior fossa malformation in fetuses: a report of 56 further cases and a review of the literature. Prenat Diagn 27(6):495–501CrossRefPubMed
Zurück zum Zitat Fox JW, Lamperti ED, Ekşioğlu YZ, Hong SE, Feng Y, Graham DA, Scheffer IE, Dobyns WB, Hirsch BA, Radtke RA, Berkovic SF, Huttenlocher PR, Walsh CA (1998) Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopias. Neuron 21(6):1315–1325CrossRefPubMed Fox JW, Lamperti ED, Ekşioğlu YZ, Hong SE, Feng Y, Graham DA, Scheffer IE, Dobyns WB, Hirsch BA, Radtke RA, Berkovic SF, Huttenlocher PR, Walsh CA (1998) Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopias. Neuron 21(6):1315–1325CrossRefPubMed
Zurück zum Zitat Gaglioti P, Danelon D, Bontempo S, Mombrò M, Cardaropoli S, Todros T (2005) Fetal cerebral ventriculomegaly: outcome in 176 cases. Ultrasound Obstet Gynecol 25(4):372–377CrossRefPubMed Gaglioti P, Danelon D, Bontempo S, Mombrò M, Cardaropoli S, Todros T (2005) Fetal cerebral ventriculomegaly: outcome in 176 cases. Ultrasound Obstet Gynecol 25(4):372–377CrossRefPubMed
Zurück zum Zitat Gaglioti P, Oberto M, Todros T (2009) The significance of fetal ventriculomegaly: etiology, short- and long-term outcomes. Prenat Diagn 29(4):381–388CrossRefPubMed Gaglioti P, Oberto M, Todros T (2009) The significance of fetal ventriculomegaly: etiology, short- and long-term outcomes. Prenat Diagn 29(4):381–388CrossRefPubMed
Zurück zum Zitat Garel C, Delezoide AL, Guibaud L, Sebag G, Gressens P, Elmaleh-Bergès M, Hassan M et al. (2004) MRI of the Fetal Brain: Normal Development and Cerebral Pathologies (V. Delezoide, Tran.) 1. Aufl. Springer Heidelberg Berlin New York, p. 267 Garel C, Delezoide AL, Guibaud L, Sebag G, Gressens P, Elmaleh-Bergès M, Hassan M et al. (2004) MRI of the Fetal Brain: Normal Development and Cerebral Pathologies (V. Delezoide, Tran.) 1. Aufl. Springer Heidelberg Berlin New York, p. 267
Zurück zum Zitat Gilles FH, Leviton A, Dooling EC (1983) The Developing human brain. growth and epidemiologic neuropathology. J. Wright Psg Inc, , S. 349 Gilles FH, Leviton A, Dooling EC (1983) The Developing human brain. growth and epidemiologic neuropathology. J. Wright Psg Inc, , S. 349
Zurück zum Zitat Glenn OA, Barkovich J (2006) Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis: part 2. AJNR Am J Neuroradiol 27(9):1807–1814PubMedPubMedCentral Glenn OA, Barkovich J (2006) Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis: part 2. AJNR Am J Neuroradiol 27(9):1807–1814PubMedPubMedCentral
Zurück zum Zitat Glover P, Hykin J, Gowland P, Wright J, Johnson I, Mansfield P (1995) An assessment of the intrauterine sound intensity level during obstetric echo-planar magnetic resonance imaging. Br J Radiol 68(814):1090–1094CrossRefPubMed Glover P, Hykin J, Gowland P, Wright J, Johnson I, Mansfield P (1995) An assessment of the intrauterine sound intensity level during obstetric echo-planar magnetic resonance imaging. Br J Radiol 68(814):1090–1094CrossRefPubMed
Zurück zum Zitat Goldstein RB, La Pidus AS, Filly RA, Cardoza J (1990) Mild lateral cerebral ventricular dilatation in utero: clinical significance and prognosis. Radiology 176(1):237–242CrossRefPubMed Goldstein RB, La Pidus AS, Filly RA, Cardoza J (1990) Mild lateral cerebral ventricular dilatation in utero: clinical significance and prognosis. Radiology 176(1):237–242CrossRefPubMed
Zurück zum Zitat Greco P, Vimercati A, Selvaggi L (2002) Isolated mild fetal cerebral ventriculomegaly. Prenat Diagn 22(2):162–163CrossRefPubMed Greco P, Vimercati A, Selvaggi L (2002) Isolated mild fetal cerebral ventriculomegaly. Prenat Diagn 22(2):162–163CrossRefPubMed
Zurück zum Zitat Gupta JK, Lilford RJ (1995) Assessment and management of fetal agenesis of the corpus callosum. Prenat Diagn 15(4):301–312CrossRefPubMed Gupta JK, Lilford RJ (1995) Assessment and management of fetal agenesis of the corpus callosum. Prenat Diagn 15(4):301–312CrossRefPubMed
Zurück zum Zitat Gupta P, Kumar S, Sharma R, Gadodia A, Roy KK, Sharma JB (2010) The role of magnetic resonance imaging in fetal renal anomalies. Int J Gynaecol Obstet 111(3):209–212CrossRefPubMed Gupta P, Kumar S, Sharma R, Gadodia A, Roy KK, Sharma JB (2010) The role of magnetic resonance imaging in fetal renal anomalies. Int J Gynaecol Obstet 111(3):209–212CrossRefPubMed
Zurück zum Zitat Hand JW, Li Y, Hajnal JV (2010) Numerical study of RF exposure and the resulting temperature rise in the foetus during a magnetic resonance procedure. Phys Med Biol 55(4):913–930CrossRefPubMed Hand JW, Li Y, Hajnal JV (2010) Numerical study of RF exposure and the resulting temperature rise in the foetus during a magnetic resonance procedure. Phys Med Biol 55(4):913–930CrossRefPubMed
Zurück zum Zitat Harper T, Fordham LA, Wolfe HM (2007) The fetal dandy walker complex: associated anomalies, perinatal outcome and postnatal imaging. Fetal Diagn Ther 22(4):277–281CrossRefPubMed Harper T, Fordham LA, Wolfe HM (2007) The fetal dandy walker complex: associated anomalies, perinatal outcome and postnatal imaging. Fetal Diagn Ther 22(4):277–281CrossRefPubMed
Zurück zum Zitat Hill BJ, Joe BN, Qayyum A, Yeh BM, Goldstein R, Coakley FV (2005) Supplemental Value of MRI in Fetal Abdominal Disease Detected on Prenatal Sonography: Preliminary Experience. AJR Am J Roentgenol 184(3):993–998CrossRefPubMed Hill BJ, Joe BN, Qayyum A, Yeh BM, Goldstein R, Coakley FV (2005) Supplemental Value of MRI in Fetal Abdominal Disease Detected on Prenatal Sonography: Preliminary Experience. AJR Am J Roentgenol 184(3):993–998CrossRefPubMed
Zurück zum Zitat Hirsch JF, Pierre-Kahn A, Renier D, Sainte-Rose C, Hoppe-Hirsch E (1984) The Dandy-Walker malformation. A review of 40 cases. J Neurosurg 61(3):515–522CrossRefPubMed Hirsch JF, Pierre-Kahn A, Renier D, Sainte-Rose C, Hoppe-Hirsch E (1984) The Dandy-Walker malformation. A review of 40 cases. J Neurosurg 61(3):515–522CrossRefPubMed
Zurück zum Zitat den Hollander NS, Vinkesteijn A, Schmitz-van Splunder P, Catsman-Berrevoets CE, Wladimiroff JW (1998) Prenatally diagnosed fetal ventriculomegaly; prognosis and outcome. Prenat Diagn 18(6):557–566CrossRef den Hollander NS, Vinkesteijn A, Schmitz-van Splunder P, Catsman-Berrevoets CE, Wladimiroff JW (1998) Prenatally diagnosed fetal ventriculomegaly; prognosis and outcome. Prenat Diagn 18(6):557–566CrossRef
Zurück zum Zitat Hörmann M, Brugger PC, Balassy C, Witzani L, Prayer D (2006) Fetal MRI of the urinary system. Eur J Radiol 57(2):303–311CrossRefPubMed Hörmann M, Brugger PC, Balassy C, Witzani L, Prayer D (2006) Fetal MRI of the urinary system. Eur J Radiol 57(2):303–311CrossRefPubMed
Zurück zum Zitat Huang H, Xue R, Zhang J, Ren T, Richards LJ, Yarowsky P, Miller MI, Mori S (2009) Anatomical characterization of human fetal brain development with diffusion tensor magnetic resonance imaging. J Neurosci 29(13):4263–4273CrossRefPubMedPubMedCentral Huang H, Xue R, Zhang J, Ren T, Richards LJ, Yarowsky P, Miller MI, Mori S (2009) Anatomical characterization of human fetal brain development with diffusion tensor magnetic resonance imaging. J Neurosci 29(13):4263–4273CrossRefPubMedPubMedCentral
Zurück zum Zitat Huisman TAGM, Kellenberger CJ (2008) MR imaging characteristics of the normal fetal gastrointestinal tract and abdomen. Eur J Radiol 65(1):170–181CrossRefPubMed Huisman TAGM, Kellenberger CJ (2008) MR imaging characteristics of the normal fetal gastrointestinal tract and abdomen. Eur J Radiol 65(1):170–181CrossRefPubMed
Zurück zum Zitat Kanal E, Barkovich AJ, Bell C, Borgstede JP, Bradley Jr WG, Froelich JW, Gilk T, Gimbel JR, Gosbee J, Kuhni-Kaminski E, Lester Jr JW, Nyenhuis J, Parag Y, Schaefer DJ, Sebek-Scoumis EA, Weinreb J, Zaremba LA, Wilcox P, Lucey L, Sass N, ACR Blue Ribbon Panel on MR Safety (2007) ACR guidance document for safe MR practices: 2007. AJR Am J Roentgenol 188(6):1447–1474CrossRefPubMed Kanal E, Barkovich AJ, Bell C, Borgstede JP, Bradley Jr WG, Froelich JW, Gilk T, Gimbel JR, Gosbee J, Kuhni-Kaminski E, Lester Jr JW, Nyenhuis J, Parag Y, Schaefer DJ, Sebek-Scoumis EA, Weinreb J, Zaremba LA, Wilcox P, Lucey L, Sass N, ACR Blue Ribbon Panel on MR Safety (2007) ACR guidance document for safe MR practices: 2007. AJR Am J Roentgenol 188(6):1447–1474CrossRefPubMed
Zurück zum Zitat Kasprian G, Brugger PC, Weber M, Krssák M, Krampl E, Herold C, Prayer D (2008) In utero tractography of fetal white matter development. NeuroImage 43(2):213–224CrossRefPubMed Kasprian G, Brugger PC, Weber M, Krssák M, Krampl E, Herold C, Prayer D (2008) In utero tractography of fetal white matter development. NeuroImage 43(2):213–224CrossRefPubMed
Zurück zum Zitat Kato M, Das S, Petras K, Kitamura K, Morohashi K, Abuelo DN, Barr M, Bonneau D, Brady AF, Carpenter NJ, Cipero KL, Frisone F, Fukuda T, Guerrini R, Iida E, Itoh M, Lewanda AF, Nanba Y, Oka A, Proud VK, Saugier-Veber P, Schelley SL, Selicorni A, Shaner R, Silengo M, Stewart F, Sugiyama N, Toyama J, Toutain A, Vargas AL, Yanazawa M, Zackai EH, Dobyns WB (2004) Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation. Hum Mutat 23(2):147–159CrossRefPubMed Kato M, Das S, Petras K, Kitamura K, Morohashi K, Abuelo DN, Barr M, Bonneau D, Brady AF, Carpenter NJ, Cipero KL, Frisone F, Fukuda T, Guerrini R, Iida E, Itoh M, Lewanda AF, Nanba Y, Oka A, Proud VK, Saugier-Veber P, Schelley SL, Selicorni A, Shaner R, Silengo M, Stewart F, Sugiyama N, Toyama J, Toutain A, Vargas AL, Yanazawa M, Zackai EH, Dobyns WB (2004) Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation. Hum Mutat 23(2):147–159CrossRefPubMed
Zurück zum Zitat Kehl S, Zirulnik A, Debus A, Sütterlin M, Siemer J, Neff W (2011) In vitro models of the fetal lung: comparison of lung volume measurements with 3-dimensional sonography and magnetic resonance imaging. J Ultrasound Med 30(8):1085–1091CrossRefPubMed Kehl S, Zirulnik A, Debus A, Sütterlin M, Siemer J, Neff W (2011) In vitro models of the fetal lung: comparison of lung volume measurements with 3-dimensional sonography and magnetic resonance imaging. J Ultrasound Med 30(8):1085–1091CrossRefPubMed
Zurück zum Zitat Klein O, Pierre-Kahn A, Boddaert N, Parisot D, Brunelle F (2003) Dandy-Walker malformation: prenatal diagnosis and prognosis. Childs Nerv Syst 19:484–489CrossRefPubMed Klein O, Pierre-Kahn A, Boddaert N, Parisot D, Brunelle F (2003) Dandy-Walker malformation: prenatal diagnosis and prognosis. Childs Nerv Syst 19:484–489CrossRefPubMed
Zurück zum Zitat Kotil K, Kilinc B, Bilge T (2008) Diagnosis and management of large occipitocervical cephaloceles: a 10-year experience. Pediatr Neurosurg 44(3):193–198CrossRefPubMed Kotil K, Kilinc B, Bilge T (2008) Diagnosis and management of large occipitocervical cephaloceles: a 10-year experience. Pediatr Neurosurg 44(3):193–198CrossRefPubMed
Zurück zum Zitat Kurtz AB, Wapner RJ, Rubin CS, Cole-Beuglet C, Ross RD, Goldberg BB (1980) Ultrasound criteria for in utero diagnosis of microcephaly. J Clin Ultrasound 8(1):11–16CrossRefPubMed Kurtz AB, Wapner RJ, Rubin CS, Cole-Beuglet C, Ross RD, Goldberg BB (1980) Ultrasound criteria for in utero diagnosis of microcephaly. J Clin Ultrasound 8(1):11–16CrossRefPubMed
Zurück zum Zitat Lee SK, Kim DI, Kim J, Kim DJ, Kim HD, Kim DS, Mori S (2005) Diffusion-tensor MR imaging and fiber tractography: a new method of describing aberrant fiber connections in developmental CNS anomalies. Radiographics 25(1):53–65 (discussion 66–68)CrossRefPubMed Lee SK, Kim DI, Kim J, Kim DJ, Kim HD, Kim DS, Mori S (2005) Diffusion-tensor MR imaging and fiber tractography: a new method of describing aberrant fiber connections in developmental CNS anomalies. Radiographics 25(1):53–65 (discussion 66–68)CrossRefPubMed
Zurück zum Zitat Lee TC, Lim FY, Keswani SG, Frischer JS, Haberman B, Kingma PS, Habli M, Jaekle RK, Sharp G, Kline-Fath B, Rubio EI, Calvo M, Guimaraes C, Crombleholme TM (2011) Late gestation fetal magnetic resonance imaging-derived total lung volume predicts postnatal survival and need for extracorporeal membrane oxygenation support in isolated congenital diaphragmatic hernia. J Pediatr Surg 46(6):1165–1171CrossRefPubMed Lee TC, Lim FY, Keswani SG, Frischer JS, Haberman B, Kingma PS, Habli M, Jaekle RK, Sharp G, Kline-Fath B, Rubio EI, Calvo M, Guimaraes C, Crombleholme TM (2011) Late gestation fetal magnetic resonance imaging-derived total lung volume predicts postnatal survival and need for extracorporeal membrane oxygenation support in isolated congenital diaphragmatic hernia. J Pediatr Surg 46(6):1165–1171CrossRefPubMed
Zurück zum Zitat Leitner Y, Goez H, Gull I, Mesterman R, Weiner E, Jaffa A, Harel S (2004) Antenatal diagnosis of central nervous system anomalies: can we predict prognosis. J Child Neurol 19(6):435–438CrossRefPubMed Leitner Y, Goez H, Gull I, Mesterman R, Weiner E, Jaffa A, Harel S (2004) Antenatal diagnosis of central nervous system anomalies: can we predict prognosis. J Child Neurol 19(6):435–438CrossRefPubMed
Zurück zum Zitat Levine D, Barnes PD (1999) Cortical maturation in normal and abnormal fetuses as assessed with prenatal MR imaging. Radiology 210(3):751–758CrossRefPubMed Levine D, Barnes PD (1999) Cortical maturation in normal and abnormal fetuses as assessed with prenatal MR imaging. Radiology 210(3):751–758CrossRefPubMed
Zurück zum Zitat Levine D, Barnes PD, Robertson RR, Wong G, Mehta TS (2003) Fast MR imaging of fetal central nervous system abnormalities. Radiology 229(1):51–61CrossRefPubMed Levine D, Barnes PD, Robertson RR, Wong G, Mehta TS (2003) Fast MR imaging of fetal central nervous system abnormalities. Radiology 229(1):51–61CrossRefPubMed
Zurück zum Zitat Levine D, Barnewolt CE, Mehta TS, Trop I, Estroff J, Wong G (2003) Fetal thoracic abnormalities: MR imaging. Radiology 228(2):379–388CrossRefPubMed Levine D, Barnewolt CE, Mehta TS, Trop I, Estroff J, Wong G (2003) Fetal thoracic abnormalities: MR imaging. Radiology 228(2):379–388CrossRefPubMed
Zurück zum Zitat Levine D, Trop I, Mehta TS, Barnes PD (2002) MR imaging appearance of fetal cerebral ventricular morphology. Radiology 223(3):652–660CrossRefPubMed Levine D, Trop I, Mehta TS, Barnes PD (2002) MR imaging appearance of fetal cerebral ventricular morphology. Radiology 223(3):652–660CrossRefPubMed
Zurück zum Zitat Limperopoulos C, Robertson Jr RL, Khwaja OS, Robson CD, Estroff JA, Barnewolt C, Levine D, Morash D, Nemes L, Zaccagnini L, du Plessis AJ (2008) How accurately does current fetal imaging identify posterior fossa anomalies. AJR Am J Roentgenol 190(6):1637–1643CrossRefPubMedPubMedCentral Limperopoulos C, Robertson Jr RL, Khwaja OS, Robson CD, Estroff JA, Barnewolt C, Levine D, Morash D, Nemes L, Zaccagnini L, du Plessis AJ (2008) How accurately does current fetal imaging identify posterior fossa anomalies. AJR Am J Roentgenol 190(6):1637–1643CrossRefPubMedPubMedCentral
Zurück zum Zitat Liu YP, Chen CP, Shih SL, Chen YF, Yang FS, Chen SC (2010) Fetal cystic lung lesions: evaluation with magnetic resonance imaging. Pediatr Pulmonol 45(6):592–600PubMed Liu YP, Chen CP, Shih SL, Chen YF, Yang FS, Chen SC (2010) Fetal cystic lung lesions: evaluation with magnetic resonance imaging. Pediatr Pulmonol 45(6):592–600PubMed
Zurück zum Zitat Malinger G, Lev D, Ben-Sira L, Hoffmann C, Vinkler H, Viñals F, Herrera M et al (2011) Can syndromic macrocephaly be diagnosed in utero. Ultrasound Obstet Gynecol 37(1):72–81CrossRefPubMed Malinger G, Lev D, Ben-Sira L, Hoffmann C, Vinkler H, Viñals F, Herrera M et al (2011) Can syndromic macrocephaly be diagnosed in utero. Ultrasound Obstet Gynecol 37(1):72–81CrossRefPubMed
Zurück zum Zitat Maricich SM, Aqeeb KA, Moayedi Y, Mathes EL, Patel MS, Chitayat D, Lyon G, Leroy JG, Zoghbi HY (2011) Pontocerebellar hypoplasia: review of classification and genetics, and exclusion of several genes known to be important for cerebellar development. J Child Neurol 26(3):288–294CrossRefPubMed Maricich SM, Aqeeb KA, Moayedi Y, Mathes EL, Patel MS, Chitayat D, Lyon G, Leroy JG, Zoghbi HY (2011) Pontocerebellar hypoplasia: review of classification and genetics, and exclusion of several genes known to be important for cerebellar development. J Child Neurol 26(3):288–294CrossRefPubMed
Zurück zum Zitat McLone DG, Dias MS (2003) The Chiari II malformation: cause and impact Child’s nervous system. Childs Nerv Syst 19:540–550CrossRefPubMed McLone DG, Dias MS (2003) The Chiari II malformation: cause and impact Child’s nervous system. Childs Nerv Syst 19:540–550CrossRefPubMed
Zurück zum Zitat Meoded A, Poretti A, Tekes A, Flammang A, Pryde S, Huisman TAGM (2011) Prenatal MR diffusion tractography in a fetus with complete corpus callosum agenesis. Neuropediatrics 42(3):122–123CrossRefPubMed Meoded A, Poretti A, Tekes A, Flammang A, Pryde S, Huisman TAGM (2011) Prenatal MR diffusion tractography in a fetus with complete corpus callosum agenesis. Neuropediatrics 42(3):122–123CrossRefPubMed
Zurück zum Zitat Milhorat TH, Bolognese PA, Nishikawa M, McDonnell NB, Francomano CA (2007) Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and chiari malformation type I in patients with hereditary disorders of connective tissue. J Neurosurg Spine 7(6):601–609CrossRefPubMed Milhorat TH, Bolognese PA, Nishikawa M, McDonnell NB, Francomano CA (2007) Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and chiari malformation type I in patients with hereditary disorders of connective tissue. J Neurosurg Spine 7(6):601–609CrossRefPubMed
Zurück zum Zitat Mitchell LA, Simon EM, Filly RA, Barkovich AJ (2000) Antenatal diagnosis of subependymal heterotopias. AJNR Am J Neuroradiol 21(2):296–300PubMedPubMedCentral Mitchell LA, Simon EM, Filly RA, Barkovich AJ (2000) Antenatal diagnosis of subependymal heterotopias. AJNR Am J Neuroradiol 21(2):296–300PubMedPubMedCentral
Zurück zum Zitat Morris JE, Rickard S, Paley MNJ, Griffiths PD, Rigby A, Whitby EH (2007) The value of in-utero magnetic resonance imaging in ultrasound diagnosed foetal isolated cerebral ventriculomegaly. Clin Radiol 62(2):140–144CrossRefPubMed Morris JE, Rickard S, Paley MNJ, Griffiths PD, Rigby A, Whitby EH (2007) The value of in-utero magnetic resonance imaging in ultrasound diagnosed foetal isolated cerebral ventriculomegaly. Clin Radiol 62(2):140–144CrossRefPubMed
Zurück zum Zitat Oh KY, Kennedy AM, Frias AE, Byrne JLB (2005) Fetal schizencephaly: pre- and postnatal imaging with a review of the clinical manifestations. Radiographics 25(3):647–657CrossRefPubMed Oh KY, Kennedy AM, Frias AE, Byrne JLB (2005) Fetal schizencephaly: pre- and postnatal imaging with a review of the clinical manifestations. Radiographics 25(3):647–657CrossRefPubMed
Zurück zum Zitat Orioli IM, Castilla EE (2010) Epidemiology of holoprosencephaly: Prevalence and risk factors. Am J Med Genet C Semin Med Genet 154(1):13–21CrossRef Orioli IM, Castilla EE (2010) Epidemiology of holoprosencephaly: Prevalence and risk factors. Am J Med Genet C Semin Med Genet 154(1):13–21CrossRef
Zurück zum Zitat Partridge SC, Mukherjee P, Berman JI, Henry RG, Glenn OA, Lu Y, Miller SP et al (2005) Tractography-based quantitation of diffusion tensor imaging parameters in white matter tracts of preterm newborns. J Magn Reson Imaging 22(4):467–474CrossRefPubMed Partridge SC, Mukherjee P, Berman JI, Henry RG, Glenn OA, Lu Y, Miller SP et al (2005) Tractography-based quantitation of diffusion tensor imaging parameters in white matter tracts of preterm newborns. J Magn Reson Imaging 22(4):467–474CrossRefPubMed
Zurück zum Zitat Poretti A, Dietrich Alber F, Brancati F, Dallapiccola B, Valente EM, Boltshauser E (2009) Normal cognitive functions in joubert syndrome. Neuropediatrics 40(6):287–290CrossRefPubMed Poretti A, Dietrich Alber F, Brancati F, Dallapiccola B, Valente EM, Boltshauser E (2009) Normal cognitive functions in joubert syndrome. Neuropediatrics 40(6):287–290CrossRefPubMed
Zurück zum Zitat Rubesova E, Vance CJ, Ringertz HG, Barth RA (2009) Three-Dimensional MRI Volumetric Measurements of the Normal Fetal Colon. AJR Am J Roentgenol 192(3):761–765CrossRefPubMed Rubesova E, Vance CJ, Ringertz HG, Barth RA (2009) Three-Dimensional MRI Volumetric Measurements of the Normal Fetal Colon. AJR Am J Roentgenol 192(3):761–765CrossRefPubMed
Zurück zum Zitat Salomon LJ, Ouahba J, Delezoide AL, Vuillard E, Oury JF, Sebag G, Garel C (2006) Third-trimester fetal MRI in isolated 10- to 12-mm ventriculomegaly: is it worth it. BJOG 113(8):942–947CrossRefPubMed Salomon LJ, Ouahba J, Delezoide AL, Vuillard E, Oury JF, Sebag G, Garel C (2006) Third-trimester fetal MRI in isolated 10- to 12-mm ventriculomegaly: is it worth it. BJOG 113(8):942–947CrossRefPubMed
Zurück zum Zitat Savelli S, Di Maurizio M, Perrone A, Tesei J, La Barbera L, Angeletti M, Francioso A et al (2007) MRI with diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) assessment in the evaluation of normal and abnormal fetal kidneys: preliminary experience. Prenat Diagn 27(12):1104–1111CrossRefPubMed Savelli S, Di Maurizio M, Perrone A, Tesei J, La Barbera L, Angeletti M, Francioso A et al (2007) MRI with diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) assessment in the evaluation of normal and abnormal fetal kidneys: preliminary experience. Prenat Diagn 27(12):1104–1111CrossRefPubMed
Zurück zum Zitat Shellock FG, Crues JV (2004) MR procedures: biologic effects, safety, and patient care. Radiology 232(3):635–652CrossRefPubMed Shellock FG, Crues JV (2004) MR procedures: biologic effects, safety, and patient care. Radiology 232(3):635–652CrossRefPubMed
Zurück zum Zitat Shellock FG, Kanal E (1999) Safety of magnetic resonance imaging contrast agents. J Magn Reson Imaging 10(3):477–484CrossRefPubMed Shellock FG, Kanal E (1999) Safety of magnetic resonance imaging contrast agents. J Magn Reson Imaging 10(3):477–484CrossRefPubMed
Zurück zum Zitat Shinmoto H, Kashima K, Yuasa Y, Ishimoto H, Morikawa Y, Tanimoto A et al (2000) MR imaging of non-CNS fetal abnormalities: a pictorial essay. Radiographics 20(5):1227–1243CrossRefPubMed Shinmoto H, Kashima K, Yuasa Y, Ishimoto H, Morikawa Y, Tanimoto A et al (2000) MR imaging of non-CNS fetal abnormalities: a pictorial essay. Radiographics 20(5):1227–1243CrossRefPubMed
Zurück zum Zitat Sonigo PC, Rypens FF, Carteret M, Delezoide AL, Brunelle FO (1998) MR imaging of fetal cerebral anomalies. Pediatr Radiol 28(4):212–222CrossRefPubMed Sonigo PC, Rypens FF, Carteret M, Delezoide AL, Brunelle FO (1998) MR imaging of fetal cerebral anomalies. Pediatr Radiol 28(4):212–222CrossRefPubMed
Zurück zum Zitat Srour M, Rioux MF, Varga C, Lortie A, Major P, Robitaille Y, Décarie JC et al (2011) The clinical spectrum of nodular heterotopias in children: report of 31 patients. Epilepsia 52(4):728–737CrossRefPubMed Srour M, Rioux MF, Varga C, Lortie A, Major P, Robitaille Y, Décarie JC et al (2011) The clinical spectrum of nodular heterotopias in children: report of 31 patients. Epilepsia 52(4):728–737CrossRefPubMed
Zurück zum Zitat Tavano A, Grasso R, Gagliardi C, Triulzi F, Bresolin N, Fabbro F, Borgatti R (2007) Disorders of cognitive and affective development in cerebellar malformations. Brain 130(Pt 10):2646–2660CrossRefPubMed Tavano A, Grasso R, Gagliardi C, Triulzi F, Bresolin N, Fabbro F, Borgatti R (2007) Disorders of cognitive and affective development in cerebellar malformations. Brain 130(Pt 10):2646–2660CrossRefPubMed
Zurück zum Zitat Ventura P, Presicci A, Perniola T, Campa MG, Margari L (2006) Mental retardation and epilepsy in patients with isolated cerebellar hypoplasia. J Child Neurol 21(9):776–781CrossRefPubMed Ventura P, Presicci A, Perniola T, Campa MG, Margari L (2006) Mental retardation and epilepsy in patients with isolated cerebellar hypoplasia. J Child Neurol 21(9):776–781CrossRefPubMed
Zurück zum Zitat Watts R, Liston C, Niogi S, Uluğ AM (2003) Fiber tracking using magnetic resonance diffusion tensor imaging and its applications to human brain development. Ment Retard Dev Disabil Res Rev 9(3):168–177CrossRefPubMed Watts R, Liston C, Niogi S, Uluğ AM (2003) Fiber tracking using magnetic resonance diffusion tensor imaging and its applications to human brain development. Ment Retard Dev Disabil Res Rev 9(3):168–177CrossRefPubMed
Zurück zum Zitat Wax JR, Bookman L, Cartin A, Pinette MG, Blackstone J (2003) Mild fetal cerebral ventriculomegaly: diagnosis, clinical associations, and outcomes. Obstet Gynecol Surv 58(6):407–414PubMed Wax JR, Bookman L, Cartin A, Pinette MG, Blackstone J (2003) Mild fetal cerebral ventriculomegaly: diagnosis, clinical associations, and outcomes. Obstet Gynecol Surv 58(6):407–414PubMed
Zurück zum Zitat Webb DW, Fryer AE, Osborne JP (1996) Morbidity associated with tuberous sclerosis: a population study. Dev Med Child Neurol 38(2):146–155CrossRefPubMed Webb DW, Fryer AE, Osborne JP (1996) Morbidity associated with tuberous sclerosis: a population study. Dev Med Child Neurol 38(2):146–155CrossRefPubMed
Metadaten
Titel
Fetale Magnetresonanztomografie
verfasst von
Chressen Catharina Remus, Dr. med.
Ruxandra Milos, Dr. med.
Ulrike Wedegärtner, Prof. Dr. med.
Copyright-Jahr
2013
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-29633-8_17

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.