nach oben

Archives of Osteoporosis

Erschienen in:

01.12.2023 | Review

Frequency of osteoporosis in Chinese patients with rheumatoid arthritis: a meta-analysis

verfasst von: Tian-Xin Chen, Zhi-Long Zhang, Sheng-Ping Yang, Yu-Qi Zhu

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2023

Einloggen, um Zugang zu erhalten

Abstract

Objective

To evaluate the current frequency of osteoporosis (OP) in Chinese patients with rheumatoid arthritis (RA) through meta-analysis.

Methods

The databases of PubMed, Web of Science, Cochrane Library, CNKI, Wan Fang, CBM, and VIP were searched for relevant literature regarding the occurrence of OP in Chinese patients with RA from January 1, 2000, to September 15, 2022. The literature was screened using inclusion and exclusion criteria, and qualifying articles were subjected to data extraction, quality evaluation, and meta-analysis using Stata 17.0 software.

Results

Altogether, 44 publications were included in this study, with a total sample size of 12,264 RA cases and 4532 patients with OP. Meta-analysis revealed that the frequency of OP in patients with RA was 37.67% [95% CI: 34.38%, 40.97%], while subgroup analysis showed that the frequency in South China was 49.43% [95% CI: 40.53%, 58.32%]. Also, the frequency in men was 29.29% [95% CI: 22.42%, 36.16%], which was significantly lower than in women (41.89% [95% CI: 36.87%, 46.90%]). The incidence rate in pre-menopausal women was only 15.19% [95% CI: 8.79%, 21.59%], much lower than the figure of 54.29% [95% CI: 45.28%, 63.30%] for post-menopausal women. Additionally, the frequency rates in the low, intermediate, and high disease activity groups were 24.52% [95% CI: 11.52%, 37.52%)], 27.67% [95% CI: 13.50%, 41.85%], and 57.96% [95% CI: 37.35%, 78.56%], respectively.

Conclusion

The frequency of OP in the Chinese RA population is higher than the world average, and patients with RA should receive standardized anti-RA therapy at an early stage, with emphasis on bone health in postmenopausal women, patients with high disease activity or longer disease duration.

Nur mit Berechtigung zugänglich

Wu HY, Cheng KM, Guo Q, Yang WG, Tong LJ, Wang WL, Sun ZM (2021) Mapping knowledge structure and themes trends of osteoporosis in rheumatoid arthritis: a bibliometric analysis. Front Med 8:787228. https://doi.org/10.3389/fmed.2021.787228CrossRef

Wang LH, Yu W, Yin XG et al (2021) Prevalence of osteoporosis and fracture in China: the China osteoporosis prevalence study. JAMA Network Open 4(8):e2121106. https://doi.org/10.1001/jamanetworkopen.2021.21106CrossRefPubMedPubMedCentral

Wysham KD, Baker JF, Shoback DM (2021) Osteoporosis and fractures in rheumatoid arthritis. Curr Opin Rheumatol 33(3):270–276. https://doi.org/10.1097/BOR.0000000000000789CrossRefPubMed

Liu YQ, Liu Y, Chen ZY, Li H, Xiao T (2021) Rheumatoid arthritis and osteoporosis: a bi-directional Mendelian randomization study. Aging 13(10):14109–14130. https://doi.org/10.18632/aging.203029CrossRefPubMedPubMedCentral

Kanis JA, Melton LJ, Christiansen CC, Johnston CC, Khaltaev N (1994) The diagnosis of osteoporosis. J Bone Miner Res 9(8):1137–1141. https://doi.org/10.1002/jbmr.5650090802CrossRefPubMed

Padrão P, Laszczyńska O, Silva-Matos C, Damasceno A, Lunet N (2012) Low fruit and vegetable consumption in Mozambique: results from a WHO STEPwise approach to chronic disease risk factor surveillance. Br J Nutr 107(3):428–435. https://doi.org/10.1017/S0007114511003023CrossRefPubMed

Cai SF, Xing QD, Feng JN, Chen JF, Xu XR (2018) Analysis of the risk factors of osteoporosis in elderly patients with rheumatoid arthritis. Chin J Osteoporosis 07:922–925+939. https://doi.org/10.3969/j.issn.1006-7108.2018.07.017CrossRef

Chen YC, Li SP, Xiang GB, Jin ZM (2018) Diagnostic value of forearm bone mineral density in postmenopausal women with rheumatoid arthritis. Zhejiang Med J 22:2466–2469. https://doi.org/10.12056/j.issn.1006-2785.2018.40.22.2018-1653CrossRef

Feng XY, Zhang FY, Chang ZF, Yang GA, Pang CY, Wang YF (2020) Relationship between osteoporosis and immunoregulatory cytokines in patients with rheumatoid arthritis. Chin J Clin Res 02:154–157. https://doi.org/10.13429/j.cnki.cjcr.2020.02.003CrossRef

10.

Gao J, Liu XJ, Kong RN, Ji LM, Pang YF, Xu MJ, Xu X, Zhao DB (2015) Changes of bone mineral density and bone metabolic biochemical markers in patients with rheumatoid arthritis. Chin J Osteoporosis 09:1119–1122. https://doi.org/10.3969/j.issn.1006-7108.2015.09.021CrossRef

11.

Gong X, Xu SQ, Liu W, Wu Y, Qi S, Ma CC, Xiao H, Xu JH (2017) Clinical research of sarcopenia and vitamin D deficiency in patients with rheumatoid arthritis and spinal osteoporotic fractures. Chin J Osteoporosis 02:221–226. https://doi.org/10.3969/j.issn.1006-7108.2017.02.018CrossRef

12.

He ZX, Cai XY, Lin XJ, Ye JH (2022) Clinical study on the changes of bone mineral density and bone metabolism indexes in elderly patients with rheumatoid arthritis complicated with sarcopenia. Chin J Osteoporosis 03:403–406+425. https://doi.org/10.3969/j.issn.1006-7108.2022.03.018CrossRef

13.

Huang D, Nan H (2020) Clinical analysis of elderly patients with rheumatoid arthritis complicated with osteoporosis. Chin J Lab Med 09:1501–1503. https://doi.org/10.3969/j.issn.1007-4287.2020.09.025CrossRef

14.

Liu W, Xu SQ, Ma XX, Hu LW, Peng LP, Xu JH (2014) Exploration of risk factors on the occurrence of osteoporotic vertebral fracture in patients with rheumatoid arthritis. Chin J Intern Med 11:852–857. https://doi.org/10.3760/cma.j.issn.0578-1426.2014.11.004CrossRef

15.

Liu CP (2019) Analysis of the occurrence and related risk factors of SOPF in the patients with RA. Shandong First Medical University

16.

Pang LN, Xu LN, Liu Y, Ma FY, Li P, Dong HY (2013) The cross-sectional research of bone mineral density in rheumatoid arthritis. Chin J Clin Electron Ed 24:11236–11240. https://doi.org/10.3877/cma.j.issn.1674-0785.2013.24.034CrossRef

17.

Rui JB, Shi DH, Qiu YY, Wang YR, Li J, Tang YY (2019) Bone metabolism changes of patients with connective tissue diseases and effects of YunKe on the patients with rheumatoid arthritis. J Nanjing Med Univ Nat Sci 07:983–987+999. https://doi.org/10.7655/NYDXBNS20190707CrossRef

18.

Shen Y (2019) Analysis of bone metabolic markers in patients with rheumatoid arthritis and its correlation with TCM syndromes. Shanghai University of Traditional Chinese Medicine

19.

Shi YM, Zhu SL, Feng XX, Liu F, Huang JL (2017) Risk factors of osteoporosis in patients with rheumatoid arthritis. Guangdong Med J S1:114–116. https://doi.org/10.3969/j.issn.1001-9448.2017.z1.043CrossRef

20.

Sun YN, Feng XY, Zeng LX, Luo J, Wang YW, Li N, He N (2019) Associations between inflammation, bone remodeling, and generalized bone loss in patients with rheumatoid arthritis. Chin J Osteoporosis 05:660–664. https://doi.org/10.3969/j.issn.1006-7108.2019.05.016CrossRef

21.

Tong H, Xu SQ, Gong X, Wang XR, Zong HX, Pan MJ, Teng YZ, Cheng MH, Xiao H, Cai J (2019) Clinical study of associations between BMI, SMI and secondary osteoporosis in patients with rheumatoid arthritis. Chin J Osteoporosis 10:1463–1468. https://doi.org/10.3969/j.issn.1006-7108.2019.10.021CrossRef

22.

Wang C, Xu SQ, Xu YC, Chen KM, Teng ZY, Li WJ, Li M, Cai J (2020) Synergistic effect of sarcopenia and osteoporosis on spinal osteoporotic fracture in patients with rheumatoid arthritis. Chin J Rheumatol 03:192–197. https://doi.org/10.3760/cma.j.issn.1007-7480.2020.03.009CrossRef

23.

Wang H (2014) The FRAX assessment of osteoporotic fracture risk in rheumatoid arthritis. WanNan Medical College

24.

Wang MJ, Zhao ZQ, Xue YJ, Liu QQ (2022) The relationship between serum YWHAH and some inflammatory factors, bone metabolism indicators and complicated osteoporosis in patients with rheumatoid arthritis. Int J Lab Med 13:1562–1566+1571. https://doi.org/10.3969/j.issn.1673-4130.2022.13.006CrossRef

25.

Wang P (2020) Study on the relationship between related factors of rheumatoid arthritis secondary osteoporosis and TCM syndrome types. Shandong University of Traditional Chinese Medicine

26.

Wang XL, Xu SQ, Wang JX, Zong HX, Chu YR, Teng ZY, Li WJ (2022) Effect of sarcopenia on spinal osteoporotic fracture in female patients with rheumatoid arthritis. J Clin Intern Med 08:539–543. https://doi.org/10.3969/j.issn.1001-9057.2022.08.011CrossRef

27.

Wang X, Yu ZM, Sun JY (2018) Changes of bone metabolism in rheumatoid arthritis with different disease activities. Zhejiang Med J 22:2462–2465+2469. https://doi.org/10.12056/j.issn.1006-2785.2018.40.22.2018-1657CrossRef

28.

Wang YY, Jia N, Wei L (2010) The clinical study of the rheumatoid arthritis patients combined with osteoporosis. Chin J Osteoporosis 11:863–868. https://doi.org/10.3969/j.issn.1006-7108.2010.11.015CrossRef

29.

Wang Y, Cao YR, Chen LJ, Li JQ, Jiang Q (2012) Factors associated with the change of bone mineral density in female patients with rheumatoid arthritis. J Bengbu Med Coll 11:1289–1293. https://doi.org/10.3969/j.issn.1000-2200.2012.11.006CrossRef

30.

Wang Y, Deng XR, Geng Y, Zhang ZL (2018) Value of forearm bone mineral density in screening osteoporosis in female patients with rheumatoid arthritis. Chin J Osteoporosis 01:52–58. https://doi.org/10.3969/j.issn.1006-7108.2018.01.013CrossRef

31.

Xu ZH, Guo JH, Yang LX, Lin TT, Zhao ZH, Cai H (2018) Analysis of the positive rate of osteoporosis in 427 rheumatoid arthritis patients. Chin J Osteoporosis 12:1573–1576+1581. https://doi.org/10.3969/j.issn.1006-7108.2018.12.003CrossRef

32.

Yan XB, Lv GR, Xu ZH, Li SL, Yan LS (2020) Correlation and prediction model of rheumatoid arthritis osteoporosis with 7 joints ultrasound score. Chin J Osteoporosis 12:1737–1741. https://doi.org/10.3969/j.issn.1006-7108.2020.12.004CrossRef

33.

Yang QZ, Zhang XF, Chen Y, Lu SH, Wang SJ (2021) A clinical study on the relationships between rheumatoid arthritis and osteoporosis. J Tradit Chin Orthopedics Traumatol 02:26–29. https://doi.org/10.3969/j.issn.1001-6015.2021.02.005CrossRef

34.

Yang WF, Zhou HQ, Sun XX, Zhang YL, Zhang SG, Peng QL, Wang GC (2014) The significance of serum bone metabolic markers in prediction of joint destruction in patients with rheumatoid arthritis. Chin J Osteoporosis 12:1402–1406. https://doi.org/10.3969/j.issn.1006-7108.2014.12.005CrossRef

35.

Yang XC, Ba YN, Li XY, Wu ZB (2014) Variation characteristics of peripheral blood β-catenin and DKK1 in patients with rheumatoid arthritis and the correlation with bone and joint damage. Chin J Postgrad Med 27:35–38. https://doi.org/10.3760/cma.j.issn.1673-4904.2014.27.013CrossRef

36.

Yu XD, Zhang Y, Li GQ, Li H, Jia JT, Meng DF, Wei H (2016) The study of the prediction of osteoporosis with rheumatoid arthritis activity in postmenopausal women. Chin J Osteoporosis 05:556–559. https://doi.org/10.3969/j.issn.1006-7108.2016.05.009CrossRef

37.

Zhang L, Hou T, Zhao JZ, Zhou JY (2022) Correlation between bone mineral density and neutrophil/lymphocyte ratio in patients with rheumatoid arthritis. Chin J Rheumatol 07(461–465):C7–C2. https://doi.org/10.3760/cma.j.cn141217-20210625-00252CrossRef

38.

Zhang S (2015) The clinical study on bone mineral density in female patients with rheumatoid arthritis. Bengbu Medical College

39.

Zhao WJ, Chang ZF, Zhao JB, Wang YF, Li Q (2022) Analysis of bone mineral density and risk factors in 1061 cases of rheumatoid arthritis. Chin J Osteoporosis 09:1321–1325+1335. https://doi.org/10.3969/j.issn.1006-7108.2022.09.012CrossRef

40.

Zou JM, Yang J, Li SY, Li M (2021) Changes of serum immunoregulatory cytokines in patients with rheumatoid arthritis complicated with osteoporosis. J Chin Physician 07:1026–1029. https://doi.org/10.3760/cma.j.cn431274-20200605-00745CrossRef

41.

Sun Y, Hong L, Gao CB (2020) The association among 14–3–3η protein, inflammation, bone remodeling and osteoporosis in patients with rheumatoid arthritis. Pak J Med Sci 36(5):872–876. https://doi.org/10.12669/pjms.36.5.2403CrossRefPubMedPubMedCentral

42.

Cheng T, Zhang SX, Wang J, Qiao J, Chang MJ, Niu HQ, Liu GY, Li XF (2022) Abnormalities of Peripheral Lymphocyte Subsets in Rheumatoid Arthritis Patients Complicated with Osteoporosis. Rheumatol Therapy 9(4):1049–1059. https://doi.org/10.1007/s40744-022-00452-xCrossRef

43.

Zou JM, Zhu LG, Yang J, Feng JF, Li SY, Luo JA, Li M, Ren Y, Dong JL, Zhang Y, Tian L (2022) Correlation between vitamin D metabolites and rheumatoid arthritis with osteoporosis by ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). J Bone Miner Metab 40(4):696–703. https://doi.org/10.1007/s00774-022-01337-3CrossRefPubMed

44.

Huang H, Wang Y, Xie WH, Geng Y, Gao D, Zhang ZL (2022) Impact of treat-to-target therapy on bone mineral density loss in patients with rheumatoid arthritis: a prospective cohort study. Front Endocrinol 13:867610. https://doi.org/10.3389/fendo.2022.867610CrossRef

45.

Qiu JJ, Lu CD, Zhang L, Zhou X, Zou HL (2022) Osteoporosis in patients with rheumatoid arthritis is associated with serum immune regulatory cellular factors. Clin Rheumatol 41(9):2685–2693. https://doi.org/10.1007/s10067-022-06212-0CrossRefPubMed

46.

Peng JH, Gong Y, Zhang YP, Xiao ZY, Zeng QY, Chen SB (2016) Bone mineral density in patients with rheumatoid arthritis and 4-year follow-up results. J Clin Rheumatol 22(2):71–74. https://doi.org/10.1097/RHU.0000000000000359CrossRefPubMed

47.

Hu ZR, Xu SM, Lin H, Ni WF, Yang QY, Qi J, Du KQ, Gu JR, Lin ZM (2020) Prevalence and risk factors for bone loss in Southern Chinese with rheumatic diseases. BMC Musculoskelet Disord 30;21(1):416. https://doi.org/10.1186/s12891-020-03403-1CrossRef

48.

Cheng TT, Yu SF, Su FM, Chen YC, Su YJ, Chiu WC, Hsu CY, Chen JF, Ko CH, Lai HM (2018) Anti-CCP-positive patients with RA have a higher 10-year probability of fracture evaluated by FRAX®: a registry study of RA with osteoporosis/fracture. Arthritis Res Ther 20(1):16. https://doi.org/10.1186/s13075-018-1515-1CrossRefPubMedPubMedCentral

49.

Meng J, Li YC, Yuan XX, Lu YW (2017) Evaluating osteoporotic fracture risk with the Fracture Risk Assessment Tool in Chinese patients with rheumatoid arthritis. Med 96(18):e6677. https://doi.org/10.1097/MD.0000000000006677CrossRef

50.

Lian L, Wang JX, Xu YC, Zong HX, Teng YZ, Xu SQ (2022) Sarcopenia may be a risk factor for osteoporosis in chinese patients with rheumatoid arthritis. Int J Gen Med 15:2075–2085. https://doi.org/10.2147/IJGM.S349435CrossRefPubMedPubMedCentral

51.

Ashai S, Harvey NC (2020) Rheumatoid arthritis and bone health. Clin Med (Lond) 20(6):565–567. https://doi.org/10.7861/clinmed.20.6.rabhCrossRefPubMed

52.

Moshayedi S, Tasorian B, Almasi-Hashiani A (2022) The prevalence of osteoporosis in rheumatoid arthritis patient: a systematic review and meta-analysis. Sci Rep 12(1):15844. https://doi.org/10.1038/s41598-022-20016-xCrossRefPubMedPubMedCentral

53.

Choi ST, Kwon S-R, Jung J-Y, Kim H-A, Kim S-S, Kim SH, Kim J-M, Park J-H, Suh C-H (2018) Prevalence and fracture risk of osteoporosis in patients with rheumatoid arthritis: a multicenter comparative study of the FRAX and WHO Criteria. J Clin Med 7(12):507. https://doi.org/10.3390/jcm7120507CrossRefPubMedPubMedCentral

54.

Chen P, Li ZZ, Hu YH (2016) Prevalence of osteoporosis in China: a meta-analysis and systematic review. BMC Public Health 16(1):1039. https://doi.org/10.1186/s12889-016-3712-7CrossRefPubMedPubMedCentral

55.

Zeng Q, Li N, Wang QQ, Feng J, Sun DM, Zhang Q, Huang JY, Wen QX, Hu R, Wang L, Ma YZ, Fu XX, Dong SY, Cheng XG (2019) The prevalence of osteoporosis in China, a nationwide, multicenter DXA survey. J Bone Miner Res 34(10):1789–1797. https://doi.org/10.1002/jbmr.3757CrossRefPubMed

56.

Yeum KJ, Song BC, Joo NS (2016) Impact of geographic location on vitamin D status and bone mineral density. Int J Environ Res Public Health 13(2):184. https://doi.org/10.3390/ijerph13020184CrossRefPubMedPubMedCentral

57.

Fogarty P, O’Beirne B, Casey C (2005) Epidemiology of the most frequent diseases in the European a-symptomatic post-menopausal women. Is there any difference between Ireland and the rest of Europe? Maturitas 52(Suppl 1):S3-6. https://doi.org/10.1016/j.maturitas.2005.06.018CrossRefPubMed

58.

Odén A, Kanis JA, McCloskey EV, Johansson H (2014) The effect of latitude on the risk and seasonal variation in hip fracture in Sweden. J Bone Miner Res 29(10):2217–2223. https://doi.org/10.1002/jbmr.2250CrossRefPubMed

59.

Xu ZC, Tang Y, Connor T, Li DP, Li YK, Liu JG (2017) Climate variability and trends at a national scale. Sci Rep 7(1):3258. https://doi.org/10.1038/s41598-017-03297-5CrossRefPubMedPubMedCentral

60.

Li X, Qiao Y, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Yan S, Xie X, Huang D, Chen J, Chen Z, Lv J, Li L (2019) China Kadoorie Biobank Collaborative Group; Tea consumption and bone health in Chinese adults: a population-based study. Osteoporos Int 30(2):333–341. https://doi.org/10.1007/s00198-018-4767-3CrossRefPubMed

61.

Messina M (2014) Soy foods, isoflavones, and the health of postmenopausal women. Am J Clin Nutr 100(Suppl 1):423S-S430. https://doi.org/10.3945/ajcn.113.071464CrossRefPubMed

62.

Raine C, Giles I (2022) What is the impact of sex hormones on the pathogenesis of rheumatoid arthritis? Front Med 9:909879. https://doi.org/10.3389/fmed.2022.909879CrossRef

63.

Favalli EG, Biggioggero M, Crotti M, Becciolini A, Raimondo MG, Meroni PL (2019) Sex and Management of Rheumatoid Arthritis. Clin Rev Allergy Immunol 56(3):333–345. https://doi.org/10.1007/s12016-018-8672-5CrossRefPubMed

64.

Upala S, Yong WC, Sanguankeo A (2017) Bone mineral density is decreased in fibromyalgia syndrome: a systematic review and meta-analysis. Rheumatol Int 37(4):617–622. https://doi.org/10.1007/s00296-016-3625-xCrossRefPubMed

65.

Schweiger JU, Schweiger U, Hüppe M, Kahl KG, Greggersen W, Fassbinder E (2016) Bone density and depressive disorder: a meta-analysis. Brain Behavior 6(8):e00489. https://doi.org/10.1002/brb3.489CrossRefPubMedPubMedCentral

66.

Forsblad-d’Elia H, Carlsten H (2011) Bone mineral density by digital X-ray radiogrammetry is strongly decreased and associated with joint destruction in long-standing rheumatoid arthritis: a cross-sectional study. BMC Musculoskelet Disord 12:242. https://doi.org/10.1186/1471-2474-12-242CrossRefPubMedPubMedCentral

67.

Suh CH (2020) Clinical characteristics of osteoporosis in patients with rheumatoid arthritis: disease activity matters. Osteoporosis Sarcopenia 6(2):37–38. https://doi.org/10.1016/j.afos.2020.05.001CrossRefPubMedPubMedCentral

68.

Abdulkhaliq A, Cheikh M, Almuntashri F, Alzahrani H, Nadwi H, Kadi E, Abed M, Janaini M, Monjed A, Janoudi N, Almoallim H (2021) A comparison of demographics, disease activity, disability, and treatment among rheumatoid arthritis patients with and without osteoporosis. Open Access Rheumatol 13:275–283. https://doi.org/10.2147/OARRR.S318810CrossRefPubMedPubMedCentral

69.

Turcotte AF, O’Connor S, Morin SN, Gibbs JC, Willie BN, Jean S, Gagnon C (2021) Association between obesity and risk of fracture, bone mineral density and bone quality in adults: A systematic review and meta-analysis. PloS One 16(6):e0252487. https://doi.org/10.1371/journal.pone.0252487CrossRefPubMedPubMedCentral

70.

Alvarez-Nemegyei J, Pacheco-Pantoja E, González-Salazar M, López-Villanueva RF, May-Kim S, Martínez-Vargas L, Quintal-Gutiérrez D (2020) Association between overweight/obesity and clinical activity in rheumatoid arthritis. Reumatol Clin 16(6):462–467. https://doi.org/10.1016/j.reuma.2018.11.005CrossRefPubMed

71.

Somers TJ, Blumenthal JA, Dorfman CS, Huffman KM, Edmond SN, Miller SN, Wren AA, Caldwell D, Keefe FJ (2022) Effects of a weight and pain management program in patients with rheumatoid arthritis with obesity: a randomized controlled pilot investigation. J Clin Rheumatol 28(1):7–13. https://doi.org/10.1097/RHU.0000000000001793CrossRefPubMed

72.

Li HQ, Wallin M, Barregard L, Sallsten G, Lundh T, Ohlsson C, Mellström D, Andersson EM (2020) Smoking-induced risk of osteoporosis is partly mediated by cadmium from tobacco smoke: the MrOS Sweden Study. J Bone Miner Res 35(8):1424–1429. https://doi.org/10.1002/jbmr.4014CrossRefPubMed

73.

Maurel DB, Boisseau N, Benhamou CL, Jaffre C (2012) Alcohol and bone: review of dose effects and mechanisms. Osteoporos Int 23(1):1–16. https://doi.org/10.1007/s00198-011-1787-7CrossRefPubMed

74.

Giuseppe DD, Alfredsson L, Bottai M, Askling J, Wolk A (2012) Long term alcohol intake and risk of rheumatoid arthritis in women: a population based cohort study. BMJ (Clin Res Ed.) 345:e4230. https://doi.org/10.1136/bmj.e4230CrossRef

75.

Scott LC, Tan R, Stahl D, Steer S, Lewis CM, Cope AP (2013) The protective effect of alcohol on developing rheumatoid arthritis: a systematic review and meta-analysis. Rheumatol (Oxford) 52(5):856–867. https://doi.org/10.1093/rheumatology/kes376CrossRef

76.

Raterman HG, Bultink IE, Lems WF (2020) Osteoporosis in patients with rheumatoid arthritis: an update in epidemiology, pathogenesis, and fracture prevention. Exp Opin Pharmacother 21(14):1725–1737. https://doi.org/10.1080/14656566.2020.1787381CrossRef

77.

Jin S, Hsieh E, Peng L, Yu C, Wang Y, Wu C, Wang Q, Li M, Zeng X (2018) Incidence of fractures among patients with rheumatoid arthritis: a systematic review and meta-analysis. Osteoporos Int 29(6):1263–1275. https://doi.org/10.1007/s00198-018-4473-1CrossRefPubMed

78.

Wang Y, Zhao R, Gu Z, Dong C, Guo G, Li L (2020) Effects of glucocorticoids on osteoporosis in rheumatoid arthritis: a systematic review and meta-analysis. Osteoporos Int 31(8):1401–1409. https://doi.org/10.1007/s00198-020-05360-wCrossRefPubMed

79.

Zhang LL, Li LD, Hong XL, Guo ZX (2022) Meta-analysis of the prevalence of osteoporosis induced by systemic glucocorticoid in Chinese population. Mod Prev Med 12:2298–2304

80.

Thakur A, Riyaz B, Patil A, Kaur A, Kapoor B, Mishra V (2018) Novel drug delivery systems for NSAIDs in management of rheumatoid arthritis: an overview. Biomed Pharmacother = Biomed Pharmacother 106:1011–1023. https://doi.org/10.1016/j.biopha.2018.07.027CrossRefPubMed

81.

Zerbini CAF, Clark P, Mendez-Sanchez L, Pereira RMR, Messina OD, Uña CR, Adachi JD, Lems WF, Cooper C, Lane NE (2017) IOF Chronic Inflammation and Bone Structure (CIBS) Working Group; Biologic therapies and bone loss in rheumatoid arthritis. Osteoporos Int 28(2):429–446. https://doi.org/10.1007/s00198-016-3769-2CrossRefPubMed

82.

Takeuchi T, Tanaka Y, Soen S, Yamanaka S, Yoneda T, Tanaka S, Nitta T, Okubo N, Genant HK, Heijde DVD (2019) Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic drugs (DESIRABLE study): a randomised, double-blind, placebo-controlled phase 3 trial. Ann Rheum Dis 78(7):899–907. https://doi.org/10.1136/annrheumdis-2018-214827CrossRefPubMed

83.

Deng L, Yao FL, Tian F, Luo XW, Yu SY, Wen ZH (2022) Influence of iguratimod on bone metabolism in patients with rheumatoid arthritis: a meta-analysis. Int J Clin Pract 2022:5684293. https://doi.org/10.1155/2022/5684293CrossRefPubMedPubMedCentral

Titel: Frequency of osteoporosis in Chinese patients with rheumatoid arthritis: a meta-analysis
verfasst von: Tian-Xin Chen
Zhi-Long Zhang
Sheng-Ping Yang
Yu-Qi Zhu
Publikationsdatum: 01.12.2023
Verlag: Springer London
Erschienen in: Archives of Osteoporosis / Ausgabe 1/2023
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-023-01212-2

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen.
» Jetzt entdecken

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Medizinstudium Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Aquatherapie bei Fibromyalgie wirksamer als Trockenübungen

03.05.2024 Fibromyalgiesyndrom Nachrichten

Bewegungs-, Dehnungs- und Entspannungsübungen im Wasser lindern die Beschwerden von Patientinnen mit Fibromyalgie besser als das Üben auf trockenem Land. Das geht aus einer spanisch-brasilianischen Vergleichsstudie hervor.

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

IT für Ärzte Nachrichten

Darauf haben viele Praxen gewartet: Das Zi hat eine Liste von Praxisverwaltungssystemen veröffentlicht, die von Nutzern positiv bewertet werden. Eine gute Grundlage für wechselwillige Ärztinnen und Psychotherapeuten.

Proximale Humerusfraktur: Auch 100-Jährige operieren?

01.05.2024 DCK 2024 Kongressbericht

Mit dem demographischen Wandel versorgt auch die Chirurgie immer mehr betagte Menschen. Von Entwicklungen wie Fast-Track können auch ältere Menschen profitieren und bei proximaler Humerusfraktur können selbst manche 100-Jährige noch sicher operiert werden.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Abstract

Objective

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2023

Bone mineral density of the ultra-distal radius: are we ignoring valuable information?

Addressing gaps in osteoporosis screening in kuwait using opportunistic quantitative computer tomography (QCT): a retrospective study

Risk factors for the comorbidity of osteoporosis/osteopenia and kidney stones: a cross-sectional study

Two-country comparison of the prescription of bone protection medication before and early after hip fracture

Mortality following fragility hip fracture in China: a record linkage study