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Erschienen in: Archives of Virology 1/2009

01.01.2009 | Brief Report

Full genome sequence of three isolates of hepatitis C virus subtype 4b from Portugal

verfasst von: Diana Koletzki, Stéphanie Dumont, Hans Vermeiren, Paula Peixe, Jaime Nina, Ricardo J. Camacho, Lieven J. Stuyver

Erschienen in: Archives of Virology | Ausgabe 1/2009

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Excerpt

Hepatitis C virus (HCV) genotype 4 has been previously shown to be prevalent in central Africa, the Middle East and, more recently, with increasing numbers in western and southern Europe. In this study, the complete genomes of three different isolates from Portugal (P212, P245 and P026) were sequenced. The open reading frame of these strains has a total of 9,036, 9,036 and 9,033 nt, respectively. Phylogenetic analysis of the complete genome revealed that these sequences grouped within genotype 4 but branched separately from the confirmed subtypes a, d, f and k. When analyzing the partial nucleotide sequence of NS5B and core, they clustered with a provisional HCV-4b sequence. Based on the data presented in this paper, we propose that these three isolates are full genome representatives of the HCV subtype 4b. …
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Metadaten
Titel
Full genome sequence of three isolates of hepatitis C virus subtype 4b from Portugal
verfasst von
Diana Koletzki
Stéphanie Dumont
Hans Vermeiren
Paula Peixe
Jaime Nina
Ricardo J. Camacho
Lieven J. Stuyver
Publikationsdatum
01.01.2009
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 1/2009
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-008-0270-z

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