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European Radiology

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30.08.2020 | Magnetic Resonance

Functional diagnosis of placenta accreta by intravoxel incoherent motion model diffusion-weighted imaging

verfasst von: Yuwei Bao, Ying Pang, Ziyan Sun, Qian Li, Dazhong Tang, Liming Xia

Erschienen in: European Radiology | Ausgabe 2/2021

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Abstract

Objectives

To investigate the diagnostic value of intravoxel incoherent motion (IVIM) DWI for placenta accreta by comparing diffusion and perfusion characteristics of placentas with accreta lesions (APs) with those of normal placentas (NPs).

Methods

Twenty-five pregnant women with AP and 24 with NP underwent 3-T magnetic resonance examinations with IVIM-DWI. The perfusion percentage (f), pseudo-diffusion coefficient (D*), and diffusion coefficient (D) values were calculated from different ROIs: the entire-plane of the AP (AP-ROI) and NP (NP-ROI) and the implanted (IR-ROI) and non-implanted region (NIR-ROI) of the AP. The AP-ROIs and NP-ROIs were compared using covariance analysis; the IR-ROIs and NIR-ROIs were compared using the Wilcoxon signed-rank test. ROC curves were produced to evaluate the parameters for predicting placenta accreta.

Results

The f and D* values for the AP-ROIs ([45.0 ± 7.63]%, [11.64 ± 2.15]mm²/s) were significantly higher than those for the NP-ROIs ([31.85 ± 5.96]%, [9.04 ± 3.13]mm²/s) (both p < 0.05); the IR-ROIs (54.8%, 14.03 mm²/s) were also significantly higher than the NIR-ROIs (37.4%, 11.4 mm²/s) (both p < 0.05). No significant differences were found between the D values of the AP-ROIs and NP-ROIs (p > 0.05) or of the IR-ROIs and NIR-ROIs (p > 0.05). The areas under the curve for f and D* of the ROC curves were 0.93 and 0.79, respectively.

Conclusions

These results suggest that the IVIM parameters f and D* can be used to quantitatively evaluate the higher perfusion of AP when compared with NP. Furthermore, IVIM may be a useful functional diagnostic technique to predict placenta accreta.

Key Points

• Intravoxel incoherent motion (IVIM) may be a useful diagnostic technique to quantitatively estimate the perfusion of the placenta.

• The perfusion percentage (f) and pseudo-diffusion coefficient (D*) values differed significantly between placentas with accreta lesions and normal placentas.

• ROC curves showed that perfusion percentage (f) and pseudo-diffusion coefficient (D*) values could accurately predict placenta accreta.

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Titel: Functional diagnosis of placenta accreta by intravoxel incoherent motion model diffusion-weighted imaging
verfasst von: Yuwei Bao
Ying Pang
Ziyan Sun
Qian Li
Dazhong Tang
Liming Xia
Publikationsdatum: 30.08.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 2/2021
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-020-07200-1

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Functional diagnosis of placenta accreta by intravoxel incoherent motion model diffusion-weighted imaging

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Objectives

Methods

Results

Conclusions

Key Points

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