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Graefe's Archive for Clinical and Experimental Ophthalmology

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22.12.2015 | Retinal Disorders

Fundus autofluorescence findings in central serous chorioretinopathy using two different confocal scanning laser ophthalmoscopes: correlation with functional and structural status

verfasst von: Joo Youn Shin, Hun Jin Choi, Jonghyun Lee, Moonjung Choi, Byunghoon Chung, Suk Ho Byeon

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 8/2016

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Abstract

Purpose

To compare autofluorescence (AF) findings using wide-field (Optomap) and conventional (HRA-AF) confocal scanning laser ophthalmoscopy (cSLO) systems in patients with central serous chorioretinopathy (CSC), and to investigate the correlations between AF findings and functional and anatomical status.

Methods

Optical coherence tomography (OCT) and AF images were compared in 73 eyes with serous retinal detachment (SRD) (group A) and 30 eyes without SRD (group B). We evaluated AF findings from the SRD region, atrophic area, and foveola. Correlations between AF findings and outer retinal abnormalities in OCT and visual acuity (VA) were analyzed.

Results

Optomap-AF was more effective than HRA-AF in identifying the margins of a detached area (P = 0.001) in group A, and for monitoring mild outer retinal damage (P = 0.041) in group B. The foveolar AF grades in both instruments were significantly correlated with VA and central foveal thickness (CFT) in both group A (Optomap, VA r _s = 0.33, P = 0.012; CFT r _s = −0.38, P = 0.002; HRA, VA r _s = 0.62, P < 0.001; CFT r _s = −0.70, P < 0.001) and group B (Optomap, VA r _s = 0.71, P < 0.001, CFT r _s = −0.78, P < 0.001; HRA, VA r _s = 0.40, P = 0.026, CFT r _s = −0.40, P = 0.030).

Conclusions

Optomap-AF was found to be advantageous for monitoring subretinal status in eyes with SRD, and more accurately reflected mild outer retinal changes in eyes without SRD. Foveolar AF grades of both imaging modalities were significantly correlated with functional and anatomical status.

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Titel: Fundus autofluorescence findings in central serous chorioretinopathy using two different confocal scanning laser ophthalmoscopes: correlation with functional and structural status
verfasst von: Joo Youn Shin
Hun Jin Choi
Jonghyun Lee
Moonjung Choi
Byunghoon Chung
Suk Ho Byeon
Publikationsdatum: 22.12.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 8/2016
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-015-3244-3

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Fundus autofluorescence findings in central serous chorioretinopathy using two different confocal scanning laser ophthalmoscopes: correlation with functional and structural status

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Purpose

Methods

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Conclusions

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