Gastric Cancer

Japanese Gastric Cancer Treatment Guidelines 2021 (6th edition)

• Open Access
• Special Article

SPK1/S1P axis confers gastrointestinal stromal tumors (GISTs) resistance of imatinib

• Original Article

Yan Chen, Rui Zhang, Dandan Mi, Qiuju Wang, Tingwenli Huang, Xinwei Dong, Hongwei Zhang, Hongtao Xiao, Sanjun Shi

Transcriptome analysis reveals the essential role of NK2 homeobox 1/thyroid transcription factor 1 (NKX2-1/TTF-1) in gastric adenocarcinoma of fundic-gland type

• Original Article

Kazushi Fukagawa, Yu Takahashi, Nobutake Yamamichi, Natsuko Kageyama-Yahara, Yoshiki Sakaguchi, Miho Obata, Rina Cho, Nobuyuki Sakuma, Sayaka Nagao, Yuko Miura, Naoki Tamura, Daisuke Ohki, Hiroya Mizutani, Seiichi Yakabi, Chihiro Minatsuki, Keiko Niimi, Yosuke Tsuji, Mitsue Yamamichi, Narumi Shigi, Shuta Tomida, Hiroyuki Abe, Tetsuo Ushiku, Kazuhiko Koike, Mitsuhiro Fujishiro

Soluble factors in malignant ascites promote the metastatic adhesion of gastric adenocarcinoma cells

• Original Article

Luai Al-Marzouki, Vivian S. Stavrakos, Sanjima Pal, Betty Giannias, France Bourdeau, Roni Rayes, Nicholas Bertos, Sara Najmeh, Jonathan D. Spicer, Jonathan Cools-Lartigue, Swneke D. Bailey, Lorenzo Ferri, Veena Sangwan

Ubiquitous mitochondrial creatine kinase promotes the progression of gastric cancer through a JNK-MAPK/JUN/HK2 axis regulated glycolysis

• Open Access
• Original Article

Yushuai Mi, Quanhui Li, Bingtian Liu, Dehai Wang, Ziping Liu, Tianshi Wang, Yuan Wang, Yifeng Zang, Yan Zhou, Yugang Wen, Yinlu Ding

IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC

• Open Access
• Original Article

Jee Hyun Kang, Suyoung Park, Jinhyung Rho, Eun-Ju Hong, Young-Eun Cho, Young-Suk Won, Hyo-Jung Kwon

Adenocarcinoma of the stomach and esophagogastric junction with low DNA methylation show poor prognoses

• Original Article

Masayuki Urabe, Keisuke Matsusaka, Tetsuo Ushiku, Masaki Fukuyo, Bahityar Rahmutulla, Hiroharu Yamashita, Yasuyuki Seto, Masashi Fukayama, Atsushi Kaneda

A multi-institutional study to evaluate the feasibility of next-generation sequencing and genomic analysis using formalin-fixed, paraffin-embedded biopsies of gastric cancer

• Original Article

Mitsuro Kanda, Masanori Terashima, Takahiro Kinoshita, Hiroshi Yabusaki, Masanori Tokunaga, Yasuhiro Kodera

Cooperation between artificial intelligence and endoscopists for diagnosing invasion depth of early gastric cancer

• Open Access
• Original Article

Atsushi Goto, Naoto Kubota, Jun Nishikawa, Ryo Ogawa, Koichi Hamabe, Shinichi Hashimoto, Hiroyuki Ogihara, Yoshihiko Hamamoto, Hideo Yanai, Osamu Miura, Taro Takami

Pertuzumab, trastuzumab, and chemotherapy in HER2-positive gastric/gastroesophageal junction cancer: end-of-study analysis of the JACOB phase III randomized clinical trial

• Open Access
• Original Article

Josep Tabernero, Paulo M. Hoff, Lin Shen, Atsushi Ohtsu, Manish A. Shah, Asna Siddiqui, Sarah Heeson, Astrid Kiermaier, Harrison Macharia, Eleonora Restuccia, Yoon-Koo Kang

Pattern of disease progression during third-line or later chemotherapy with nivolumab associated with poor prognosis in advanced gastric cancer: a multicenter retrospective study in Japan

• Open Access
• Original Article

Masahiko Aoki, Shigenori Kadowaki, Naoki Takahashi, Takeshi Suzuki, Kotoe Oshima, Takayuki Ando, Yoshiyuki Yamamoto, Kentaro Kawakami, Yosuke Kito, Toshihiko Matsumoto, Keitaro Shimozaki, Yasuhiro Miyazaki, Toshifumi Yamaguchi, Michitaka Nagase, Takao Tamura, Yusuke Amanuma, Taito Esaki, Yuji Miura, Kohei Akiyoshi, Eishi Baba, Akitaka Makiyama, Yuji Negoro, Koji Nakashima, Naotoshi Sugimoto, Kengo Nagashima, Hirokazu Shoji, Narikazu Boku

A continuous muscle-sparing advantage of pylorus-preserving gastrectomy for older patients with cT1N0M0 gastric cancer in the middle third of the stomach

• Original Article

Masayoshi Terayama, Manabu Ohashi, Rie Makuuchi, Masaru Hayami, Satoshi Ida, Koshi Kumagai, Takeshi Sano, Souya Nunobe

Feasibility and safety of inserting transient biodegradable stents in the pylorus during pylorus-preserving gastrectomy for gastric cancer: a preliminary study in a porcine for proof of concept

• Original Article

Ji-Hyeon Park, Hyesung Yoon, Yoon Jin Kwak, Chaojie Wang, Khalid Mohammed Alzahrani, Sen Wang, Fadhel Dhaifallah H. Alzahrani, Hyun Myong Kim, Eunhee Koo, Ja Eun Yoo, Jong-Ho Choi, Shin-Hoo Park, Seong-Ho Kong, Do Joong Park, Hyuk-Joon Lee, Han-Kwang Yang

Correction to: Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences

• Open Access
• Correction

Alison Rowsell, Samantha C. Sodergren, Vassilios Vassiliou, Anne-Sophie Darlington, Marianne G. Guren, Bilal Alkhaffaf, Chantelle Moorbey, Kristopher Dennis, Mitsumi Terada