Erschienen in:
01.02.2013 | Original Article
Genetic Animal Models of Preconditioning
verfasst von:
Priti Azad, Gabriel G. Haddad
Erschienen in:
Translational Stroke Research
|
Ausgabe 1/2013
Einloggen, um Zugang zu erhalten
Abstract
The preconditioning phenomena have been well established in the heart as well as in the brain. In this review, we detail some of the original studies on preconditioning as well as studies from our lab using rodents and a genetic model system (fruit fly). We have used Drosophila in our lab to solve some of the questions related to tolerance or susceptibility to hypoxia. We believe that these pro-survival strategies and genetic pathways help us understand some of the preconditioning mechanisms that protect the brain from ischemia.