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Erschienen in: Journal of Behavioral Medicine 5/2015

01.10.2015

Genetic counseling content: How does it impact health behavior?

verfasst von: Kimberly M. Kelly, Lee Ellington, Nancy Schoenberg, Thomas Jackson, Stephanie Dickinson, Kyle Porter, Howard Leventhal, Michael Andrykowski

Erschienen in: Journal of Behavioral Medicine | Ausgabe 5/2015

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Abstract

Women with hereditary breast-ovarian cancer face decisions about screening (transvaginal ultrasound, CA125, mammography, breast exams) and proactive (before cancer) or reactive (after cancer) surgery (oophorectomy, mastectomy). The content of genetic counseling and its relation to these key health behaviors is largely unexamined. Ashkenazi Jewish women (n = 78) were surveyed through the process of genetic testing and had audiorecorded counseling sessions available for Linguistic Inquiry and Word Count analysis. Proportions for participant and counselor cognitive and affective content during sessions were used as primary predictor variables in linear mixed models for change in intentions for screening and treatment and in self-reported screening. Cognitive and affective content were important predictors of behavior. Counselor cognitive content was associated with ovarian screening. An interaction effect also emerged for CA-125, such that counselor cognitive content plus participant cognitive content or counselor affective content were associated with more screening. Teasing out the factors in risk communication that impact decision-making are critical, and affect from a risk communicator can spur action, such as cancer screening.
Literatur
Zurück zum Zitat Beattie, M. S., Copeland, K., Fehniger, J., Cheung, E., Joseph, G., Lee, R., et al. (2013). Genetic counseling, cancer screening, breast cancer characteristics, and general health among a diverse population of BRCA genetic testers. Journal of Health Care for the Poor and Underserved, 24, 1150–1166.CrossRefPubMed Beattie, M. S., Copeland, K., Fehniger, J., Cheung, E., Joseph, G., Lee, R., et al. (2013). Genetic counseling, cancer screening, breast cancer characteristics, and general health among a diverse population of BRCA genetic testers. Journal of Health Care for the Poor and Underserved, 24, 1150–1166.CrossRefPubMed
Zurück zum Zitat Botkin, J. R., Smith, K. R., Croyle, R. T., Baty, B. J., Wylie, J. E., Dutson, D., et al. (2003). Genetic testing for a BRCA1 mutation: Prophylactic surgery and screening behavior in women 2 years post testing. American Journal of Medical Genetics, Part A, 118, 201–209.CrossRef Botkin, J. R., Smith, K. R., Croyle, R. T., Baty, B. J., Wylie, J. E., Dutson, D., et al. (2003). Genetic testing for a BRCA1 mutation: Prophylactic surgery and screening behavior in women 2 years post testing. American Journal of Medical Genetics, Part A, 118, 201–209.CrossRef
Zurück zum Zitat Burke, W., Daly, M., Garber, J. E., Botkin, J. R., Kahn, M. E., Lynch, P., et al. (1997). Recommendations for follow-up care of individuals with an inherited prediposition to cancer II. BRCA1 and BRCA2. Journal of the American Medical Association, 277, 997–1003.CrossRefPubMed Burke, W., Daly, M., Garber, J. E., Botkin, J. R., Kahn, M. E., Lynch, P., et al. (1997). Recommendations for follow-up care of individuals with an inherited prediposition to cancer II. BRCA1 and BRCA2. Journal of the American Medical Association, 277, 997–1003.CrossRefPubMed
Zurück zum Zitat Coughlin, S., King, J., Richards, T., & Ekwueme, D. (2005). Breast cancer screening and socioeconomic status—35 metropolitan areas, 2000 and 2002. Morbidity and Mortality Weekly Report, 59, 982–986. Coughlin, S., King, J., Richards, T., & Ekwueme, D. (2005). Breast cancer screening and socioeconomic status—35 metropolitan areas, 2000 and 2002. Morbidity and Mortality Weekly Report, 59, 982–986.
Zurück zum Zitat Dorval, M., Nogues, C., Berthet, P., Chiquette, J., Gauthier-Villars, M., Lasset, C., et al. (2011). Breast and ovarian cancer screening of non-carriers from BRCA1/2 mutation-positive families: 2-year follow-up of cohorts from France and Quebec. European Journal of Human Genetics, 19, 494–499.PubMedCentralCrossRefPubMed Dorval, M., Nogues, C., Berthet, P., Chiquette, J., Gauthier-Villars, M., Lasset, C., et al. (2011). Breast and ovarian cancer screening of non-carriers from BRCA1/2 mutation-positive families: 2-year follow-up of cohorts from France and Quebec. European Journal of Human Genetics, 19, 494–499.PubMedCentralCrossRefPubMed
Zurück zum Zitat Doughty Rice, C., Ruschman, J. G., Martin, L. J., Manders, J. B., & Miller, E. (2010). Retrospective comparison of patient outcomes after in-person and telephone results disclosure counseling for BRCA1/2 genetic testing. Familial Cancer, 9, 203–212.CrossRefPubMed Doughty Rice, C., Ruschman, J. G., Martin, L. J., Manders, J. B., & Miller, E. (2010). Retrospective comparison of patient outcomes after in-person and telephone results disclosure counseling for BRCA1/2 genetic testing. Familial Cancer, 9, 203–212.CrossRefPubMed
Zurück zum Zitat Easton, D. F., Ford, D., Bishop, T., & The Breast Cancer Linkage Consortium. (1995). Breast and ovarian cancer incidence in BRCA1-mutation carriers. American Journal of Human Genetics, 56, 265–271.PubMedCentralPubMed Easton, D. F., Ford, D., Bishop, T., & The Breast Cancer Linkage Consortium. (1995). Breast and ovarian cancer incidence in BRCA1-mutation carriers. American Journal of Human Genetics, 56, 265–271.PubMedCentralPubMed
Zurück zum Zitat Ellington, L., Baty, B. J., McDonald, J., Venne, V., Musters, A., Roter, D., et al. (2006). Exploring genetic counseling communication patterns: The role of teaching and counseling approaches. Journal of Genetic Counseling, 15, 179–189.CrossRefPubMed Ellington, L., Baty, B. J., McDonald, J., Venne, V., Musters, A., Roter, D., et al. (2006). Exploring genetic counseling communication patterns: The role of teaching and counseling approaches. Journal of Genetic Counseling, 15, 179–189.CrossRefPubMed
Zurück zum Zitat Ellington, L., Roter, D., Dudley, W. N., Baty, B. J., Upchurch, R., Larson, S., et al. (2005). Communication analysis of BRCA1 genetic counseling. Journal of Genetic Counseling, 14, 337–386.CrossRef Ellington, L., Roter, D., Dudley, W. N., Baty, B. J., Upchurch, R., Larson, S., et al. (2005). Communication analysis of BRCA1 genetic counseling. Journal of Genetic Counseling, 14, 337–386.CrossRef
Zurück zum Zitat Finch, A., Beiner, M., Lubinski, J., Lynch, H. T., Moller, P., Rosen, B., … &Hereditary Ovarian Cancer Clinical Study Group. (2006). Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation. Journal of the American Medical Association, 296(2), 185–192. Finch, A., Beiner, M., Lubinski, J., Lynch, H. T., Moller, P., Rosen, B., … &Hereditary Ovarian Cancer Clinical Study Group. (2006). Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation. Journal of the American Medical Association, 296(2), 185–192.
Zurück zum Zitat Fitzgerald, M. G., MacDonald, D. J., Krainer, M., Hoover, I., O’Neil, E., Unsal, H., … & Haber, D. A. (1996). Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer. The New England Journal of Medicine, 334(3), 143–149. Fitzgerald, M. G., MacDonald, D. J., Krainer, M., Hoover, I., O’Neil, E., Unsal, H., … & Haber, D. A. (1996). Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer. The New England Journal of Medicine, 334(3), 143–149.
Zurück zum Zitat Graves, K. D., Schmidt, J. E., & Andrykowski, M. A. (2005). Writing about September 11, 2001: The role of emotional intelligence and the social environment. Journal of Language and Social Psychology, 24, 285–299. Graves, K. D., Schmidt, J. E., & Andrykowski, M. A. (2005). Writing about September 11, 2001: The role of emotional intelligence and the social environment. Journal of Language and Social Psychology, 24, 285–299.
Zurück zum Zitat Halbert, C. H., Stopfer, J. E., McDonald, J., Weathers, B., Collier, A., Troxel, A. B., et al. (2011). Long-term reactions to genetic testing for BRCA1 and BRCA2 mutations: Does time heal women’s concerns? Journal of Clinical Oncology, 29, 4302–4306.PubMedCentralCrossRefPubMed Halbert, C. H., Stopfer, J. E., McDonald, J., Weathers, B., Collier, A., Troxel, A. B., et al. (2011). Long-term reactions to genetic testing for BRCA1 and BRCA2 mutations: Does time heal women’s concerns? Journal of Clinical Oncology, 29, 4302–4306.PubMedCentralCrossRefPubMed
Zurück zum Zitat Hartmann, L. C., Schaid, D. J., Woods, J. E., Crotty, T. P., Myers, J. L., Arnold, P. G., … & Jenkins, R. B. et al. (1999). Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer. New England Journal of Medicine, 340(2), 77–84. Hartmann, L. C., Schaid, D. J., Woods, J. E., Crotty, T. P., Myers, J. L., Arnold, P. G., … & Jenkins, R. B. et al. (1999). Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer. New England Journal of Medicine, 340(2), 77–84.
Zurück zum Zitat Howard, A. F., Balneaves, L. G., & Bottorff, J. L. (2009). Women’s decision making about risk-reducing strategies in the context of hereditary breast and ovarian cancer: A systematic review. Journal of Genetic Counseling, 18, 578–597.CrossRefPubMed Howard, A. F., Balneaves, L. G., & Bottorff, J. L. (2009). Women’s decision making about risk-reducing strategies in the context of hereditary breast and ovarian cancer: A systematic review. Journal of Genetic Counseling, 18, 578–597.CrossRefPubMed
Zurück zum Zitat Johnson, J. D. (1997). Cancer-related information seeking. Creeskill, NJ: Hampton Press Inc. Johnson, J. D. (1997). Cancer-related information seeking. Creeskill, NJ: Hampton Press Inc.
Zurück zum Zitat Kahn, J. A., Slap, G. B., Bernstein, D. I., Tissot, A. M., Kollar, L. M., Hilliard, P. A., et al. (2007). Personal meaning of human papillomavirus and pap test results in adolescent and young adult women. Health Psychology, 26, 192–200.CrossRefPubMed Kahn, J. A., Slap, G. B., Bernstein, D. I., Tissot, A. M., Kollar, L. M., Hilliard, P. A., et al. (2007). Personal meaning of human papillomavirus and pap test results in adolescent and young adult women. Health Psychology, 26, 192–200.CrossRefPubMed
Zurück zum Zitat Kelly, K. M., Ellington, L., Schoenberg, N., Agarwal, P., Jackson, T., Dickinson, S., … Andrykowski, M. (2014). Linking genetic counseling content to short-term outcomes in individuals at elevated breast cancer risk. Journal of Genetic Counseling, 23, 838–848. Kelly, K. M., Ellington, L., Schoenberg, N., Agarwal, P., Jackson, T., Dickinson, S., … Andrykowski, M. (2014). Linking genetic counseling content to short-term outcomes in individuals at elevated breast cancer risk. Journal of Genetic Counseling, 23, 838–848.
Zurück zum Zitat Kelly, K., Leventhal, H., Andrykowski, M., Toppmeyer, D., Much, J., Dermody, J., … Scwalb, M. (2004a). The decision to test in women receiving genetic counseling for BRCA1 and BRCA2 mutations. Journal of Genetic Counseling, 13, 237–257.CrossRefPubMed Kelly, K., Leventhal, H., Andrykowski, M., Toppmeyer, D., Much, J., Dermody, J., … Scwalb, M. (2004a). The decision to test in women receiving genetic counseling for BRCA1 and BRCA2 mutations. Journal of Genetic Counseling, 13, 237–257.CrossRefPubMed
Zurück zum Zitat Kelly, K. M., Leventhal, H., Marvin, M., Toppmeyer, D., Much, J., Dermody, J., et al. (2004b). Subjective and objective risk of breast cancer in Ashkenazi Jewish individuals at risk for BRCA1/2 mutations. Genetic Testing, 8, 139–147.CrossRefPubMed Kelly, K. M., Leventhal, H., Marvin, M., Toppmeyer, D., Much, J., Dermody, J., et al. (2004b). Subjective and objective risk of breast cancer in Ashkenazi Jewish individuals at risk for BRCA1/2 mutations. Genetic Testing, 8, 139–147.CrossRefPubMed
Zurück zum Zitat Kinney, A. Y., Simonsen, S. E., Baty, B. J., Mandal, D., Neuhausen, S. L., Seggar, K., et al. (2006). Risk reduction behaviors and provider communication following genetic counseling and BRCA1 mutation testing in an African American kindred. Journal of Genetic Counseling, 15, 293–305.CrossRefPubMed Kinney, A. Y., Simonsen, S. E., Baty, B. J., Mandal, D., Neuhausen, S. L., Seggar, K., et al. (2006). Risk reduction behaviors and provider communication following genetic counseling and BRCA1 mutation testing in an African American kindred. Journal of Genetic Counseling, 15, 293–305.CrossRefPubMed
Zurück zum Zitat Lerman, C., Hughes, C., Croyle, R. T., Main, D., Durham, C., Snyder, C., et al. (2000). Prophylactic surgery decisions and surveillance practices one year following BRCA1/2 testing. Preventive Medicine, 31, 75–80.CrossRefPubMed Lerman, C., Hughes, C., Croyle, R. T., Main, D., Durham, C., Snyder, C., et al. (2000). Prophylactic surgery decisions and surveillance practices one year following BRCA1/2 testing. Preventive Medicine, 31, 75–80.CrossRefPubMed
Zurück zum Zitat Leventhal, H., Benyamini, Y., Brownlee, S., Diefenbach, M., Leventhal, E. A., & Patrick-Miller, L. (1997). Illness representation: Theoretical foundations. In J. Weinman & K. Petrie (Eds.), Perceptions of health and illness (pp. 19–45). London: Harwood. Leventhal, H., Benyamini, Y., Brownlee, S., Diefenbach, M., Leventhal, E. A., & Patrick-Miller, L. (1997). Illness representation: Theoretical foundations. In J. Weinman & K. Petrie (Eds.), Perceptions of health and illness (pp. 19–45). London: Harwood.
Zurück zum Zitat Leventhal, H., Brisette, I., & Leventhal, E. (2003). The common-sense model of self-regulation of health and illness. In L. D. Cameron & H. Leventhal (Eds.), The self-regulation of health and illness behaviour (pp. 42–65). London: Routledge. Leventhal, H., Brisette, I., & Leventhal, E. (2003). The common-sense model of self-regulation of health and illness. In L. D. Cameron & H. Leventhal (Eds.), The self-regulation of health and illness behaviour (pp. 42–65). London: Routledge.
Zurück zum Zitat Loader, S., Shields, C. G., & Rowley, P. T. (2004). Impact of genetic testing for breast-ovarian cancer susceptibility. Genetic Testing, 8, 1–12.CrossRefPubMed Loader, S., Shields, C. G., & Rowley, P. T. (2004). Impact of genetic testing for breast-ovarian cancer susceptibility. Genetic Testing, 8, 1–12.CrossRefPubMed
Zurück zum Zitat Lodder, L. N., Frets, P. G., Trijsburg, R. W., Meijers-Heijboer, E. J., Klijn, J. G., Seynaeve, C., et al. (2002). One year follow-up of women opting for presymptomatic testing for BRCA1 and BRCA2: Emotional impact of the test outcome and decisions on risk management (surveillance or prophylactic surgery). Breast Cancer Research and Treatment, 73, 97–112.CrossRefPubMed Lodder, L. N., Frets, P. G., Trijsburg, R. W., Meijers-Heijboer, E. J., Klijn, J. G., Seynaeve, C., et al. (2002). One year follow-up of women opting for presymptomatic testing for BRCA1 and BRCA2: Emotional impact of the test outcome and decisions on risk management (surveillance or prophylactic surgery). Breast Cancer Research and Treatment, 73, 97–112.CrossRefPubMed
Zurück zum Zitat Mannis, G. N., Fehniger, J. E., Creasman, J. S., Jacoby, V. L., & Beattie, M. S. (2013). Risk-reducing salpingo-oophorectomy and ovarian cancer screening in 1077 women after BRCA testing. Journal of the American Medical Association Internal Medicine, 173, 96–103.PubMed Mannis, G. N., Fehniger, J. E., Creasman, J. S., Jacoby, V. L., & Beattie, M. S. (2013). Risk-reducing salpingo-oophorectomy and ovarian cancer screening in 1077 women after BRCA testing. Journal of the American Medical Association Internal Medicine, 173, 96–103.PubMed
Zurück zum Zitat Mehl, M., & Pennebaker, J. (2003). The sounds of social life: A psychometric analysis of students’ daily social environments and natural conversations. Journal of Personality and Social Psychology, 84, 857–870.CrossRefPubMed Mehl, M., & Pennebaker, J. (2003). The sounds of social life: A psychometric analysis of students’ daily social environments and natural conversations. Journal of Personality and Social Psychology, 84, 857–870.CrossRefPubMed
Zurück zum Zitat Meiser, B., Butow, P. N., Barratt, A. L., Schnieden, V., Gattas, M., Kirk, J., et al. (2001). Long-term outcomes of genetic counseling in women at increased risk of developing hereditary breast cancer. Patient Education and Counseling, 44, 215–225.CrossRefPubMed Meiser, B., Butow, P. N., Barratt, A. L., Schnieden, V., Gattas, M., Kirk, J., et al. (2001). Long-term outcomes of genetic counseling in women at increased risk of developing hereditary breast cancer. Patient Education and Counseling, 44, 215–225.CrossRefPubMed
Zurück zum Zitat Miller, A. B., Baines, C. J., To, T., & Wall, C. (1992). Canadian National Breast Screening Study: 2. Breast cancer detection and death rates among women aged 50 to 59 years. Canadian Medical Association Journal, 147, 1477–1488.PubMedCentralPubMed Miller, A. B., Baines, C. J., To, T., & Wall, C. (1992). Canadian National Breast Screening Study: 2. Breast cancer detection and death rates among women aged 50 to 59 years. Canadian Medical Association Journal, 147, 1477–1488.PubMedCentralPubMed
Zurück zum Zitat Miller, S. M., Roussi, P., Daly, M. B., Buzaglo, J. S., Sherman, K., Godwin, A. K., et al. (2005). Enhanced counseling for women undergoing BRCA1/2 testing: Impact on subsequent decision making about risk reduction behaviors. Health Education and Behavior, 32, 654–667.CrossRefPubMed Miller, S. M., Roussi, P., Daly, M. B., Buzaglo, J. S., Sherman, K., Godwin, A. K., et al. (2005). Enhanced counseling for women undergoing BRCA1/2 testing: Impact on subsequent decision making about risk reduction behaviors. Health Education and Behavior, 32, 654–667.CrossRefPubMed
Zurück zum Zitat Morgan, D., Sylvester, H., Lucas, F. L., & Miesfeldt, S. (2009). Cancer prevention and screening practices among women at risk for hereditary breast and ovarian cancer after genetic counseling in the community setting. Familial Cancer, 8, 277–287.CrossRefPubMed Morgan, D., Sylvester, H., Lucas, F. L., & Miesfeldt, S. (2009). Cancer prevention and screening practices among women at risk for hereditary breast and ovarian cancer after genetic counseling in the community setting. Familial Cancer, 8, 277–287.CrossRefPubMed
Zurück zum Zitat Morris, K. T., Johnson, N., Krasikov, N., Allen, M., & Dorsey, P. (2001). Genetic counseling impacts decision for prophylactic surgery for patients perceived to be at high risk for breast cancer. American Journal of Surgery, 181, 431–433.CrossRefPubMed Morris, K. T., Johnson, N., Krasikov, N., Allen, M., & Dorsey, P. (2001). Genetic counseling impacts decision for prophylactic surgery for patients perceived to be at high risk for breast cancer. American Journal of Surgery, 181, 431–433.CrossRefPubMed
Zurück zum Zitat Moyer, V. A., & US Preventive Services Task Force. (2014). Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force Recommendation Statement. Annals of Internal Medicine, 160(4), 271–281. Moyer, V. A., & US Preventive Services Task Force. (2014). Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force Recommendation Statement. Annals of Internal Medicine, 160(4), 271–281.
Zurück zum Zitat National Society of Genetic Counselors. (2004). Familial Cancer Risk Counseling Association: Standard Protocol. Retrieved 12/5/2008, from www.nsgc.org National Society of Genetic Counselors. (2004). Familial Cancer Risk Counseling Association: Standard Protocol. Retrieved 12/5/2008, from www.​nsgc.​org
Zurück zum Zitat Niederhoffer, K., & Pennebaker, J. (2002). Linguistic style matching in social interaction. Journal of Language and Social Psychology, 21, 337–360. Niederhoffer, K., & Pennebaker, J. (2002). Linguistic style matching in social interaction. Journal of Language and Social Psychology, 21, 337–360.
Zurück zum Zitat Nystrom, L., Andersson, I., Bjurstam, N., Frisell, J., Nordenskjold, B., & Rutqvist, L. E. (2002). Long-term effects of mammography screening: Updated overview of the Swedish randomised trials. Lancet, 359, 909–919.CrossRefPubMed Nystrom, L., Andersson, I., Bjurstam, N., Frisell, J., Nordenskjold, B., & Rutqvist, L. E. (2002). Long-term effects of mammography screening: Updated overview of the Swedish randomised trials. Lancet, 359, 909–919.CrossRefPubMed
Zurück zum Zitat Obermaier, A., Youlden, D. R., Baade, P. D., & Janda, M. (2014). The impact of risk-reducing hysterectomy and bilateral salpingo-oophorectomy on survival in patients with a history of breast cancer—A population-based data linkage study. International Journal of Cancer, 134, 2211–2222.CrossRef Obermaier, A., Youlden, D. R., Baade, P. D., & Janda, M. (2014). The impact of risk-reducing hysterectomy and bilateral salpingo-oophorectomy on survival in patients with a history of breast cancer—A population-based data linkage study. International Journal of Cancer, 134, 2211–2222.CrossRef
Zurück zum Zitat Oddoux, C., Struewing, J. P., Clayton, C. M., Neuhausen, S., Brody, L. C., Kaback, M. M., … & Offit, K. (1996). The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%. Nature Genetics, 14, 188–190. Oddoux, C., Struewing, J. P., Clayton, C. M., Neuhausen, S., Brody, L. C., Kaback, M. M., … & Offit, K. (1996). The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%. Nature Genetics, 14, 188–190.
Zurück zum Zitat Olivier, R. I., Lubsen-Brandsma, M. A., Verhoef, S., & van Beurden, M. (2006). CA125 and transvaginal ultrasound monitoring in high-risk women cannot prevent the diagnosis of advanced ovarian cancer. Gynecologic Oncology, 100, 20–26.CrossRefPubMed Olivier, R. I., Lubsen-Brandsma, M. A., Verhoef, S., & van Beurden, M. (2006). CA125 and transvaginal ultrasound monitoring in high-risk women cannot prevent the diagnosis of advanced ovarian cancer. Gynecologic Oncology, 100, 20–26.CrossRefPubMed
Zurück zum Zitat O’Neill, S. C., Valdimarsdottir, H. B., Demarco, T. A., Peshkin, B. N., Graves, K. D., Brown, K., et al. (2010). BRCA1/2 test results impact risk management attitudes, intentions, and uptake. Breast Cancer Research and Treatment, 124, 755–764.PubMedCentralCrossRefPubMed O’Neill, S. C., Valdimarsdottir, H. B., Demarco, T. A., Peshkin, B. N., Graves, K. D., Brown, K., et al. (2010). BRCA1/2 test results impact risk management attitudes, intentions, and uptake. Breast Cancer Research and Treatment, 124, 755–764.PubMedCentralCrossRefPubMed
Zurück zum Zitat Pennebaker, J., & Francis, M. (2001). Linguistic Inquiry and Word Count. The Second Version: SLIWC. University of Texas at Austin. Pennebaker, J., & Francis, M. (2001). Linguistic Inquiry and Word Count. The Second Version: SLIWC. University of Texas at Austin.
Zurück zum Zitat Pennebaker, J. F., Francis, M. E., & Booth, R. J. (2001). Linguistic inquiry and word count LIWC 2001. Mahway: Lawrence Erlbaum Associates. Pennebaker, J. F., Francis, M. E., & Booth, R. J. (2001). Linguistic inquiry and word count LIWC 2001. Mahway: Lawrence Erlbaum Associates.
Zurück zum Zitat Peshkin, B. N., Schwartz, M. D., Isaacs, C., Hughes, C., Main, D., & Lerman, C. (2002). Utilization of breast cancer screening in a clinically based sample of women after BRCA1/2 testing. Cancer Epidemiology, Biomarkers and Prevention, 11, 1115–1118.PubMed Peshkin, B. N., Schwartz, M. D., Isaacs, C., Hughes, C., Main, D., & Lerman, C. (2002). Utilization of breast cancer screening in a clinically based sample of women after BRCA1/2 testing. Cancer Epidemiology, Biomarkers and Prevention, 11, 1115–1118.PubMed
Zurück zum Zitat Ray, J. A., Loescher, L. J., & Brewer, M. (2005). Risk-reduction surgery decisions in high-risk women seen for genetic counseling. Journal of Genetic Counseling, 14, 473–484.CrossRefPubMed Ray, J. A., Loescher, L. J., & Brewer, M. (2005). Risk-reduction surgery decisions in high-risk women seen for genetic counseling. Journal of Genetic Counseling, 14, 473–484.CrossRefPubMed
Zurück zum Zitat Saadatmand, S., Tilanus-Linthorst, M. M., Rutgers, E. J., Hoogerbrugge, N., Oosterwijk, J. C., Tollenaar, R. A., ... de Koning, H. J. (2013). Cost-effectiveness of screening women with familial risk for breast cancer with magnetic resonance imaging. Journal of the National Cancer Institute, 105, 1314–1321. Saadatmand, S., Tilanus-Linthorst, M. M., Rutgers, E. J., Hoogerbrugge, N., Oosterwijk, J. C., Tollenaar, R. A., ... de Koning, H. J. (2013). Cost-effectiveness of screening women with familial risk for breast cancer with magnetic resonance imaging. Journal of the National Cancer Institute, 105, 1314–1321.
Zurück zum Zitat Scheuer, L., Kauff, N., Robson, M., Kelly, B., Barakat, R., Satagopan, J., et al. (2002). Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers. Journal of Clinical Oncology, 20, 1260–1268.CrossRefPubMed Scheuer, L., Kauff, N., Robson, M., Kelly, B., Barakat, R., Satagopan, J., et al. (2002). Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers. Journal of Clinical Oncology, 20, 1260–1268.CrossRefPubMed
Zurück zum Zitat Schwartz, M. D., Isaacs, C., Graves, K. D., Poggi, E., Peshkin, B. N., Gell, C., et al. (2012). Long-term outcomes of BRCA1/BRCA2 testing: Risk reduction and surveillance. Cancer, 118, 510–517.PubMedCentralCrossRefPubMed Schwartz, M. D., Isaacs, C., Graves, K. D., Poggi, E., Peshkin, B. N., Gell, C., et al. (2012). Long-term outcomes of BRCA1/BRCA2 testing: Risk reduction and surveillance. Cancer, 118, 510–517.PubMedCentralCrossRefPubMed
Zurück zum Zitat Schwartz, M. D., Kaufman, E., Peshkin, B. N., Isaacs, C., Hughes, C., DeMarco, T., et al. (2003). Bilateral prophylactic oophorectomy and ovarian cancer screening following BRCA1/BRCA2 mutation testing. Journal of Clinical Oncology, 21, 4034–4041.CrossRefPubMed Schwartz, M. D., Kaufman, E., Peshkin, B. N., Isaacs, C., Hughes, C., DeMarco, T., et al. (2003). Bilateral prophylactic oophorectomy and ovarian cancer screening following BRCA1/BRCA2 mutation testing. Journal of Clinical Oncology, 21, 4034–4041.CrossRefPubMed
Zurück zum Zitat Schwartz, M. D., Rimer, B. K., Daly, M., Sands, C., & Lerman, C. (1999). A randomized trial of breast cancer risk counseling: The impact on self-reported mammography use. American Journal of Public Health, 89, 924–926.PubMedCentralCrossRefPubMed Schwartz, M. D., Rimer, B. K., Daly, M., Sands, C., & Lerman, C. (1999). A randomized trial of breast cancer risk counseling: The impact on self-reported mammography use. American Journal of Public Health, 89, 924–926.PubMedCentralCrossRefPubMed
Zurück zum Zitat Tonin, P., Weber, B., Offit, K., Couch, F., Rebbeck, T. R., Neuhausen, S., et al. (1996). Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nature Medicine, 2, 1179–1183.CrossRefPubMed Tonin, P., Weber, B., Offit, K., Couch, F., Rebbeck, T. R., Neuhausen, S., et al. (1996). Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nature Medicine, 2, 1179–1183.CrossRefPubMed
Zurück zum Zitat van Driel, C. M., Eltahir, Y., de Vries, J., Jaspers, J. P., Oosterwijk, J. C., Mourits, M. J., et al. (2014). Risk-reducing mastectomy in BRCA1/2 mutation carriers: Factors influencing uptake and timing. Maturitas, 77, 180–184.CrossRefPubMed van Driel, C. M., Eltahir, Y., de Vries, J., Jaspers, J. P., Oosterwijk, J. C., Mourits, M. J., et al. (2014). Risk-reducing mastectomy in BRCA1/2 mutation carriers: Factors influencing uptake and timing. Maturitas, 77, 180–184.CrossRefPubMed
Zurück zum Zitat Vasen, H. F., Tesfay, E., Boonstra, H., Mourits, M. J., Rutgers, E., Verheyen, R., et al. (2005). Early detection of breast and ovarian cancer in families with BRCA mutations. European Journal of Cancer, 41, 549–554.CrossRefPubMed Vasen, H. F., Tesfay, E., Boonstra, H., Mourits, M. J., Rutgers, E., Verheyen, R., et al. (2005). Early detection of breast and ovarian cancer in families with BRCA mutations. European Journal of Cancer, 41, 549–554.CrossRefPubMed
Zurück zum Zitat Wainberg, S., & Husted, J. (2004). Utilization of screening and preventive surgery among unaffected carriers of a BRCA1 or BRCA2 gene mutation. Cancer Epidemiology, Biomarkers and Prevention, 13, 1989–1995.PubMed Wainberg, S., & Husted, J. (2004). Utilization of screening and preventive surgery among unaffected carriers of a BRCA1 or BRCA2 gene mutation. Cancer Epidemiology, Biomarkers and Prevention, 13, 1989–1995.PubMed
Metadaten
Titel
Genetic counseling content: How does it impact health behavior?
verfasst von
Kimberly M. Kelly
Lee Ellington
Nancy Schoenberg
Thomas Jackson
Stephanie Dickinson
Kyle Porter
Howard Leventhal
Michael Andrykowski
Publikationsdatum
01.10.2015
Verlag
Springer US
Erschienen in
Journal of Behavioral Medicine / Ausgabe 5/2015
Print ISSN: 0160-7715
Elektronische ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-014-9613-2

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