Background
Materials and methods
Study data
Estimation framework
Attributable burden
Statistical analysis
Results
Breast cancer incidence burden
Characteristics | 1990 | 2017 | 1990-2017 | ||
---|---|---|---|---|---|
Incidence cases No. × 103 (95% UI) | ASR per 100,000 No. (95% UI) | Incidence cases No. × 103 (95% UI) | ASR per 100,000 No. (95% UI) | EAPC No. (95% CI) | |
Overall | 878.7 (846.0–935.7) | 20.91 (20.18–22.16) | 1960.7 (1891.4–2023.2) | 24.19 (23.34–24.96) | 0.42 (0.35–0.47) |
Sex | |||||
Male | 8.5 (8.2–8.9) | 0.46 (0.44–0.48) | 23.1 (22.3–24.0) | 0.61 (0.59–0.64) | 1.17 (1.01–1.34) |
Female | 870.2 (837.7–927.1) | 39.19 (37.77–41.66) | 1937.6 (1868.0–2000.4) | 45.91 (44.24–47.40) | 0.45 (0.38–0.51) |
Social-demographic index | |||||
Low | 30.0 (23.6–42.0) | 7.61 (6.10–10.53) | 94.4 (86.9–102.7) | 11.62 (10.70–12.70) | 1.44 (1.22–1.67) |
Low middle | 67.8 (56.5–89.4) | 10.25 (8.62–13.33) | 222.6 (199.3–275.6) | 16.50 (17.75–20.62) | 1.65 (1.58–1.72) |
Middle | 115.6 (106.6–130.0) | 10.43 (9.71–11.66) | 418.9 (378.2–444.1) | 17.86 (16.12–18.92) | 1.95 (1.87–2.03) |
Middle high | 165.7 (157.8–177.6) | 16.63 (15.86–17.82) | 436.0 (400.4–458.7) | 23.93 (22.00–25.15) | 1.27 (1.17–1.37) |
High | 497.4 (491.8–503.3) | 40.92 (40.47–41.41) | 781.3 (757.5–804.4) | 40.99 (39.76–42.21) | − 0.13 (− 0.25–0.01) |
Region | |||||
Central Asia | 7.7 (7.4–8.0) | 14.90 (14.43–15.40) | 16.6 (15.5–17.8) | 19.66 (18.43–21.00) | 1.06 (1.00–1.12) |
Central Europe | 36.6 (35.6–37.7) | 24.92 (24.25–25.62) | 60.4 (57.6–63.4) | 32.05 (30.60–33.70) | 0.97 (0.85–1.08) |
Eastern Europe | 63.1 (60.4–65.9) | 22.97 (21.93–23.98) | 97.2 (93.5–100.8) | 30.64 (29.43–31.85) | 0.82 (0.56–1.08) |
Australasia | 9.7 (9.4–10.0) | 42.18 (40.84–43.65) | 18.8 (16.4–21.4) | 44.22 (38.38–50.73) | − 0.10 (− 0.29–0.09) |
High-income Asia Pacific | 34.0 (33.0–35.1) | 16.35 (15.87–16.85) | 91.9 (85.8–97.8) | 27.03 (25.31–28.75) | 2.32 (2.02–2.62) |
High-income North America | 198.2 (195.0–201.4) | 58.43 (57.51–59.38) | 276.9 (266.9–287.8) | 49.34 (47.62–51.52) | − 1.04 (− 1.20–0.88) |
Southern Latin America | 10.9 (10.5–11.3) | 23.21 (22.36–24.14) | 22.7 (20.2–25.5) | 28.78 (25.69–32.45) | 0.62 (0.45–0.80) |
Western Europe | 233.9 (229.9–237.9) | 44.13 (43.39–44.92) | 341.8 (324.9–358.9) | 45.41 (43.21–47.65) | 0.02 (− 0.14–0.19) |
Andean Latin America | 2.1 (1.9–2.4) | 9.01 (8.19–10.07) | 8.3 (7.3–9.6) | 14.77 (12.92–17.07) | 1.82 (1.62–2.02) |
Caribbean | 5.5 (5.1–6.0) | 20.06 (18.74–21.94) | 14.2 (12.6–15.9) | 27.85 (24.80–31.29) | 1.16 (1.09–1.23) |
Central Latin America | 13.2 (12.9–13.5) | 13.35 (13.06–13.67) | 51.4 (48.7–54.2) | 21.09 (20.01–22.21) | 1.49 (1.35–1.64) |
Tropical Latin America | 16.4 (16.0–16.9) | 15.69 (15.31–16.07) | 54.4 (52.5–56.2) | 22.52 (21.79–23.28) | 1.15 (0.89–1.42) |
North Africa and Middle East | 20.3 (16.7–27.7) | 9.77 (8.15–13.21) | 91.2 (85.2–100.6) | 18.06 (16.90–20.28) | 2.49 (2.27–2.70) |
South Asia | 53.7 (46.7–67.3) | 7.61 (6.70–9.47) | 210.8 (182.3–248.9) | 14.07 (12.17–16.61) | 2.03 (1.81–2.25) |
East Asia | 99.0 (89.5–120.5) | 9.43 (8.55–11.52) | 386.5 (326.1–417.0) | 18.41 (15.49–19.86) | 2.63 (2.42–2.85) |
Oceania | 0.6 (0.5–0.9) | 16.28 (13.49–22.11) | 1.7 (1.3–2.4) | 20.15 (15.82–26.69) | 0.86 (0.83–0.89) |
Southeast Asia | 41.7 (34.5–51.6) | 13.04 (10.98–15.92) | 125.6 (115.2–135.9) | 18.70 (17.22-20.19) | 1.30 (1.23–1.36) |
Central Sub-Saharan Africa | 2.7 (1.9–4.2) | 9.87 (7.37–14.73) | 8.1 (6.2–10.7) | 13.32 (10.70–17.01) | 0.99 (0.90–1.08) |
Eastern Sub-Saharan Africa | 10.4 (8.0–14.3) | 11.17 (8.85–15.22) | 25.6 (22.3–29.5) | 12.9 (11.4–14.8) | 0.27 (0.09–0.44) |
Southern Sub-Saharan Africa | 4.2 (3.9–4.6) | 13.23 (12.07–14.67) | 10.5 (9.5–11.4) | 17.44 (15.75–18.82) | 1.02 (0.49–1.55) |
Western Sub-Saharan Africa | 14.6 (10.2–20.8) | 14.41 (10.11–20.28) | 46.1 (35.1–61.0) | 20.57 (15.80–26.95) | 1.34 (1.22–1.46) |
Breast cancer deaths and DALY burden
Region metric | All ages × 103 (95% UI) | Age-standardized rate/100,000 (95% UI) | ||||||
---|---|---|---|---|---|---|---|---|
2017 no. male + female | 2017 no. male | 2017 no. female | % 1990–2017 change | 2017 male + female | 2017 male | 2017 female | % 1990–2017 change | |
Global | ||||||||
Deaths | 611.6 (589.2–640.7) | 10.9 (10.5–11.4) | 600.7 (578.7–629.9) | 74.96 (57.34–87.02) | 7.65 (7.37–8.01) | 0.30 (0.29–0.31) | 14.14 (13.63–14.84) | − 11.66 (− 20.06–6.02) |
DALYs | 17708.6 (16899.5–18675.0) | 285.5 (272.8–299.4) | 17423.1 (16617.5–18378.2) | 69.73 (49.96–84.04) | 216.3 (206.4–228.1) | 7.28 (6.96–7.64) | 414.7 (395.5–437.6) | − 9.24(− 19.51–1.88) |
High SDI | ||||||||
Deaths | 181.0 (176.1–186.1) | 2.5 (2.4–2.6) | 178.5 (173.6–183.6) | 16.48 (13.05–19.68) | 8.42 (8.18–8.64) | 0.25 (0.24–0.26) | 15.37 (14.94–15.78) | − 32.23 (− 34.22–30.42) |
DALYs | 4290.9 (4080.9–4514.7) | 52.5 (49.8–55.8) | 4238.4 (4030.9–4460.0) | 5.63 (2.03–8.81) | 231.2 (220.0–243.1) | 5.65 (5.35–6.00) | 440.6 (419.5–463.6) | − 31.67 (− 34.00–29.53) |
High middle SDI | ||||||||
Deaths | 123.4 (114.3–128.2) | 2.2 (2.1–2.3) | 121.2 (112.1–126.0) | 72.76 (46.19–84.08) | 6.89 (6.38–7.16) | 0.27 (0.25–0.28) | 12.58 (11.65–13.09) | − 8.37(− 22.48–2.52) |
DALYs | 3536.3 (3259.6–3720.8) | 58.2 (54.4–62.0) | 3478.1 (3203.1–3663.6) | 59.30 (34.20–71.26) | 192.3 (177.0–202.4) | 6.66 (6.23–7.09) | 366.7 (337.5–386.3) | − 12.17(− 26.10–5.59) |
Middle SDI | ||||||||
Deaths | 142.5 (128.5–150.4) | 3.1 (2.9–3.3) | 139.4 (125.5–147.4) | 144.64 (96.48–172.78) | 6.32 (5.70–6.67) | 0.29 (0.27–0.31) | 11.83 (10.64–12.50) | 10.59 (− 11.08–22.71) |
DALYs | 4433.9 (3996.3–4723.9) | 86.6 (80.5–92.8) | 4347.3 (3909.3–4637.7) | 126.21 (82.70–154.77) | 185.9 (167.2–197.9) | 7.56 (7.02–8.09) | 357.4 (320.7–381.1) | 9.12 (− 12.08–22.40) |
Middle-low SDI | ||||||||
Deaths | 108.0 (96.0–137.0) | 1.7 (1.6–1.9) | 106.3 (94.3–135.2) | 154.40 (85.42–218.23) | 8.59 (7.62–10.99) | 0.31 (0.29–0.33) | 16.30 (14.44–20.89) | 24.10 (− 8.76–52.76) |
DALYs | 3569.7 (3178.2–4459.9) | 48.9 (45.6–52.2) | 3520.8 (3131.0–4409.3) | 149.61 (80.17–217.70) | 257.2 (229.1–322.6) | 7.74 (7.20–8.24) | 498.1 (443.1–626.1) | 24.63 (− 9.51–57.13) |
Low SDI | ||||||||
Deaths | 54.8 (50.5–59.9) | 1.4 (1.2–1.5) | 53.5 (49.2–58.6) | 159.35 (85.72–223.84) | 7.31 (6.72–7.95) | 0.43 (0.38–0.47) | 14.02 (12.90–15.34) | 26.93 (− 8.42–56.46) |
DALYs | 1819.8 (1680.3–1980.8) | 37.7 (34.2–41.2) | 1782.1 (1642.6–1943.8) | 149.04 (77.91–217.13) | 214.7 (198.4–233.7) | 9.81 (8.83–10.70) | 417.5 (385.0–455.5) | 22.74 (− 12.23–54.50) |