Skip to main content
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 7/2021

14.04.2021 | Cataract

Global multi-site, prospective analysis of cataract surgery outcomes following ICHOM standards: the European CAT-Community

verfasst von: Bart LM Zijlmans, Rogier van Zijderveld, Michele Manzulli, Gonzaga Garay-Aramburu, Philipp Czapski, Nicole Eter, Raphael Diener, Josep Torras, Daniele Tognetto, Rosa Giglio, Chiara De Giacinto, Joaquin Fernandez, Clare O’Donnell, David P. Piñero, Annemijn Knitel, Roberto Bergado-Mijangos, Daniel Coello-Ojeda, Itziar Ozaeta, Beatriz Macias-Murelaga, Jesús Garrido Fierro, Cristian E Dalmasso, Pío Jesús Garcia-Gómez, Mari Himanka, Javier Martínez, Meilin Chang-Sotomayor, Anna Camós-Carreras, Felipe Spencer, Noelia Sabater-Cruz, Carlo Scardellato, Carmen Dell’Aquila, Giulia Pian, European CAT-Community Study Group

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 7/2021

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To evaluate in a large sample of patients from 10 different European centers the results of cataract surgery, characterizing the relationship between patient-reported outcomes (PROMs) and clinician-reported outcome measures (CROMs).

Methods

Prospective non-interventional multicenter observational descriptive study analyzing the clinical outcomes of a total of 3799 cases undergoing cataract surgery (mean age: 72.7 years). In all cases, the cataract surgery standard developed by the International Consortium for Health Outcomes Measurements (ICHOM) was used to register the clinical data. Three-month postoperative visual acuity and refraction data were considered CROMs, whereas Rasch-calibrated item 2 (RCCQ2) and total Catquest-9SF score (CQ) were considered PROMs.

Results

Postoperative corrected distance visual acuity (CDVA) was 0.3 logMAR or better in 88.7% (2505/2823) of eyes. Mean differences between preoperative and postoperative RCCQ2 and CQ scores were −3.09 and −2.39, respectively. Visual function improvement with surgery was reported by 91.5% (2163/2364) of patients. Statistically significant, although weak, correlations of postoperative CDVA with postoperative refraction, PROMs, and complications were found (0.133 ≤ r ≤0.289, p < 0.001). A predictive model (R2: 0.254) of postoperative CDVA considering 10 variables was obtained, including preoperative CDVA, different ocular comorbidities, age, gender and intraoperative complications. Likewise, another predictive model (R2: 0.148) of postoperative CQ considering a total of 14 variables was obtained, including additionally preoperative CQ, target refraction and previous surgeries.

Conclusions

Cataract surgery provides an improved functional vision in most of patients although this improvement can be limited by ocular comorbidities and complications. The relationship between PROMs and CROMs is multifactorial and complex.
Literatur
1.
Zurück zum Zitat Refolo P, Minacori R, Mele V, Sacchini D, Spagnolo AG (2012) Patient reported outcomes (PROs): the significance of using humanistic measures in clinical trial and clinical practice. Eur Rev Med PharmacolSci 16:1319Y23 Refolo P, Minacori R, Mele V, Sacchini D, Spagnolo AG (2012) Patient reported outcomes (PROs): the significance of using humanistic measures in clinical trial and clinical practice. Eur Rev Med PharmacolSci 16:1319Y23
2.
Zurück zum Zitat Staniszewska S, Haywood KL, Brett J, Tutton L (2012) Patient and public involvement in patient-reported outcome measures: evolution not revolution. Patient 5:79–87CrossRef Staniszewska S, Haywood KL, Brett J, Tutton L (2012) Patient and public involvement in patient-reported outcome measures: evolution not revolution. Patient 5:79–87CrossRef
3.
Zurück zum Zitat Lundstrom M, Pesudovs K (2009) Catquest-9SF patient outcomes questionnaire: nine-item short-form Rasch-scaled revision of the Catquest questionnaire. J Cataract Refract Surg 35:504–13CrossRef Lundstrom M, Pesudovs K (2009) Catquest-9SF patient outcomes questionnaire: nine-item short-form Rasch-scaled revision of the Catquest questionnaire. J Cataract Refract Surg 35:504–13CrossRef
4.
Zurück zum Zitat Lundstrom M, Stenevi U (2013) Analyzing patient-reported outcomes to improve cataract care. Optom Vis Sci 90:754–9CrossRef Lundstrom M, Stenevi U (2013) Analyzing patient-reported outcomes to improve cataract care. Optom Vis Sci 90:754–9CrossRef
5.
Zurück zum Zitat McNamara RL, Spatz ES, Kelley TA, Stowell CJ, Beltrame J, Heidenreich P, Tresserras R, Jernberg T, Chua T, Morgan L, Panigrahi B, Rosas Ruiz A, Rumsfeld JS, Sadwin JS, Schoeberl M, Shahian D, Weston C, Yeh R, Lewin J (2015) Standardized outcome measurement for patients with coronary artery disease: consensus from the International Consortium for Health Outcomes Measurement (ICHOM). J Am Heart Assoc 4(5):e001767 McNamara RL, Spatz ES, Kelley TA, Stowell CJ, Beltrame J, Heidenreich P, Tresserras R, Jernberg T, Chua T, Morgan L, Panigrahi B, Rosas Ruiz A, Rumsfeld JS, Sadwin JS, Schoeberl M, Shahian D, Weston C, Yeh R, Lewin J (2015) Standardized outcome measurement for patients with coronary artery disease: consensus from the International Consortium for Health Outcomes Measurement (ICHOM). J Am Heart Assoc 4(5):e001767
6.
Zurück zum Zitat Bell D, Kelley T, Hicks N (2015) How true outcomes-based commissioning can really ‘liberate’ healthcare services. Future Hosp J 2:147–149CrossRef Bell D, Kelley T, Hicks N (2015) How true outcomes-based commissioning can really ‘liberate’ healthcare services. Future Hosp J 2:147–149CrossRef
7.
Zurück zum Zitat Michelotti M, de Korne DF, Weizer JS, Lee PP, Flanagan D, Kelly SP, Odergren A, Sandhu SS, Wai C, Klazinga N, Haripriya A, Stein JD, Hingorani M (2017) Mapping standard ophthalmic outcome sets to metrics currently reported in eight eye hospitals. BMC Ophthalmol 17:269CrossRef Michelotti M, de Korne DF, Weizer JS, Lee PP, Flanagan D, Kelly SP, Odergren A, Sandhu SS, Wai C, Klazinga N, Haripriya A, Stein JD, Hingorani M (2017) Mapping standard ophthalmic outcome sets to metrics currently reported in eight eye hospitals. BMC Ophthalmol 17:269CrossRef
8.
Zurück zum Zitat Mahmud I, Kelly T, Stowell C, Haripriya A, Boman A, Kossler I, Morlet N, Pershing S, Pesudovs K, Goh PP, Sparrow JM, Lundström M (2015) A proposed minimum standard set of outcomes measures for cataract surgery. JAMA Ophthalmol 133:1247–1252CrossRef Mahmud I, Kelly T, Stowell C, Haripriya A, Boman A, Kossler I, Morlet N, Pershing S, Pesudovs K, Goh PP, Sparrow JM, Lundström M (2015) A proposed minimum standard set of outcomes measures for cataract surgery. JAMA Ophthalmol 133:1247–1252CrossRef
9.
Zurück zum Zitat Yan W, Wang W, van Wijngaarden P, Mueller A, He M (2019) Longitudinal changes in global cataract surgery rate inequality and associations with socioeconomic indices. ClinExpOphthalmol 47:453–460 Yan W, Wang W, van Wijngaarden P, Mueller A, He M (2019) Longitudinal changes in global cataract surgery rate inequality and associations with socioeconomic indices. ClinExpOphthalmol 47:453–460
11.
Zurück zum Zitat McAlinden C, Gothwal VK, Khadka J, Wright TA, Lamoureux EL, Pesudovs K (2011) A head-to-head comparison of 16 cataract surgery outcome questionnaires. Ophthalmology 118:2374–81CrossRef McAlinden C, Gothwal VK, Khadka J, Wright TA, Lamoureux EL, Pesudovs K (2011) A head-to-head comparison of 16 cataract surgery outcome questionnaires. Ophthalmology 118:2374–81CrossRef
12.
Zurück zum Zitat Davidorf JM (2015) Femtosecond versus (gold) standard phacoemulsification. J Cataract Refract Surg 41:1124CrossRef Davidorf JM (2015) Femtosecond versus (gold) standard phacoemulsification. J Cataract Refract Surg 41:1124CrossRef
13.
Zurück zum Zitat Lotfipour M, Rolius R, Lehman EB, Pantanelli SM, Scott IU (2017) Trends in cataract surgery training curricula. J Cataract Refract Surg 43:49–53CrossRef Lotfipour M, Rolius R, Lehman EB, Pantanelli SM, Scott IU (2017) Trends in cataract surgery training curricula. J Cataract Refract Surg 43:49–53CrossRef
14.
Zurück zum Zitat Thanigasalam T, Reddy SC, Zaki RA (2015) Factors associated with complications and postoperative visual outcomes of cataract surgery; a study of 1,632 cases. J Ophthalmic Vis Res 10:375–84CrossRef Thanigasalam T, Reddy SC, Zaki RA (2015) Factors associated with complications and postoperative visual outcomes of cataract surgery; a study of 1,632 cases. J Ophthalmic Vis Res 10:375–84CrossRef
15.
Zurück zum Zitat Lundström M, Barry P, Henry Y, Rosen P, Stenevi U (2013) Visual outcome of cataract surgery; study from the European Registry of Quality Outcomes for Cataract and Refractive Surgery. J Cataract Refract Surg 39:673–9CrossRef Lundström M, Barry P, Henry Y, Rosen P, Stenevi U (2013) Visual outcome of cataract surgery; study from the European Registry of Quality Outcomes for Cataract and Refractive Surgery. J Cataract Refract Surg 39:673–9CrossRef
16.
Zurück zum Zitat Chaudhary V, Popovic M, Holmes J, Robinson T, Mak M, Mohammad Mohaghegh PS, Eino D, Mann K, Kobetz L, Gusenbauer K, Barbosa J (2016) Predictors of functional vision changes after cataract surgery: the PROVISION study. Can J Ophthalmol 51:265–270CrossRef Chaudhary V, Popovic M, Holmes J, Robinson T, Mak M, Mohammad Mohaghegh PS, Eino D, Mann K, Kobetz L, Gusenbauer K, Barbosa J (2016) Predictors of functional vision changes after cataract surgery: the PROVISION study. Can J Ophthalmol 51:265–270CrossRef
17.
Zurück zum Zitat Fung SS, Luis J, Hussain B, Bunce C, Hingorani M, Hancox J (2016) Patient-reported outcome measuring tools in cataract surgery: clinical comparison at a tertiary hospital. J Cataract Refract Surg 42:1759–1767CrossRef Fung SS, Luis J, Hussain B, Bunce C, Hingorani M, Hancox J (2016) Patient-reported outcome measuring tools in cataract surgery: clinical comparison at a tertiary hospital. J Cataract Refract Surg 42:1759–1767CrossRef
18.
Zurück zum Zitat Grimfors M, Mollazadegan K, Lundström M, Kugelberg M (2014) Ocular comorbidity and self-assessed visual function after cataract surgery. J Cataract Refract Surg 40:1163–9CrossRef Grimfors M, Mollazadegan K, Lundström M, Kugelberg M (2014) Ocular comorbidity and self-assessed visual function after cataract surgery. J Cataract Refract Surg 40:1163–9CrossRef
19.
Zurück zum Zitat Harrer A, Gerstmeyer K, Hirnschall N, Pesudovs K, Lundström M, Findl O (2013) Impact of bilateral cataract surgery on vision-related activity limitations. J Cataract Refract Surg 39:680–5CrossRef Harrer A, Gerstmeyer K, Hirnschall N, Pesudovs K, Lundström M, Findl O (2013) Impact of bilateral cataract surgery on vision-related activity limitations. J Cataract Refract Surg 39:680–5CrossRef
20.
Zurück zum Zitat Helbostad JL, Oedegaard M, Lamb SE, Delbaere K, Lord SR, Sletvold O (2013) Change in vision, visual disability, and health after cataract surgery. Optom Vis Sci 90:392–9CrossRef Helbostad JL, Oedegaard M, Lamb SE, Delbaere K, Lord SR, Sletvold O (2013) Change in vision, visual disability, and health after cataract surgery. Optom Vis Sci 90:392–9CrossRef
21.
Zurück zum Zitat Lundström M, Llovet F, Llovet A, Martinez del Pozo M, Mompean B, González JV, Pesudovs K (2016) Validation of the Spanish Catquest-9SF in patients with a monofocal or trifocal intraocular lens. J Cataract Refract Surg 42:1791–1796CrossRef Lundström M, Llovet F, Llovet A, Martinez del Pozo M, Mompean B, González JV, Pesudovs K (2016) Validation of the Spanish Catquest-9SF in patients with a monofocal or trifocal intraocular lens. J Cataract Refract Surg 42:1791–1796CrossRef
22.
Zurück zum Zitat Mollazadegan K, Lundström M (2015) A study of the correlation between patient-reported outcomes and clinical outcomes after cataract surgery in ophthalmic clinics. ActaOphthalmol 93:293–8 Mollazadegan K, Lundström M (2015) A study of the correlation between patient-reported outcomes and clinical outcomes after cataract surgery in ophthalmic clinics. ActaOphthalmol 93:293–8
23.
Zurück zum Zitat Stolk-Vos AC, Visser MS, Klijn S, Timman R, Lansink P, Nuijts R, Tjia K, Zijlmans B, Kranenburg LW, Busschbach JV, Reus NJ (2018) Effects of clinical parameters on patient-reported outcome in cataract patients: a multicentre study. ActaOphthalmol 96:586–591 Stolk-Vos AC, Visser MS, Klijn S, Timman R, Lansink P, Nuijts R, Tjia K, Zijlmans B, Kranenburg LW, Busschbach JV, Reus NJ (2018) Effects of clinical parameters on patient-reported outcome in cataract patients: a multicentre study. ActaOphthalmol 96:586–591
24.
Zurück zum Zitat Grimfors M, Lundström M, Höijer J, Kugelberg M (2018) Intraoperative difficulties, complications and self-assessed visual function in cataract surgery. ActaOphthalmol 96:592–599 Grimfors M, Lundström M, Höijer J, Kugelberg M (2018) Intraoperative difficulties, complications and self-assessed visual function in cataract surgery. ActaOphthalmol 96:592–599
25.
Zurück zum Zitat Rönbeck M, Lundström M, Kugelberg M (2011) Study of possible predictors associated with self-assessed visual function after cataract surgery. Ophthalmology 118:1732–8CrossRef Rönbeck M, Lundström M, Kugelberg M (2011) Study of possible predictors associated with self-assessed visual function after cataract surgery. Ophthalmology 118:1732–8CrossRef
26.
Zurück zum Zitat Nderitu P, Ursell P (2019) Factors affecting cataract surgery operating time among trainees and consultants. J Cataract Refract Surg 45:816–822CrossRef Nderitu P, Ursell P (2019) Factors affecting cataract surgery operating time among trainees and consultants. J Cataract Refract Surg 45:816–822CrossRef
Metadaten
Titel
Global multi-site, prospective analysis of cataract surgery outcomes following ICHOM standards: the European CAT-Community
verfasst von
Bart LM Zijlmans
Rogier van Zijderveld
Michele Manzulli
Gonzaga Garay-Aramburu
Philipp Czapski
Nicole Eter
Raphael Diener
Josep Torras
Daniele Tognetto
Rosa Giglio
Chiara De Giacinto
Joaquin Fernandez
Clare O’Donnell
David P. Piñero
Annemijn Knitel
Roberto Bergado-Mijangos
Daniel Coello-Ojeda
Itziar Ozaeta
Beatriz Macias-Murelaga
Jesús Garrido Fierro
Cristian E Dalmasso
Pío Jesús Garcia-Gómez
Mari Himanka
Javier Martínez
Meilin Chang-Sotomayor
Anna Camós-Carreras
Felipe Spencer
Noelia Sabater-Cruz
Carlo Scardellato
Carmen Dell’Aquila
Giulia Pian
European CAT-Community Study Group
Publikationsdatum
14.04.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 7/2021
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-021-05181-5

Weitere Artikel der Ausgabe 7/2021

Graefe's Archive for Clinical and Experimental Ophthalmology 7/2021 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Ophthalmika in der Schwangerschaft

Die Verwendung von Ophthalmika in der Schwangerschaft und Stillzeit stellt immer eine Off-label-Anwendung dar. Ein Einsatz von Arzneimitteln muss daher besonders sorgfältig auf sein Risiko-Nutzen-Verhältnis bewertet werden. In der vorliegenden …

Operative Therapie und Keimnachweis bei endogener Endophthalmitis

Vitrektomie Originalie

Die endogene Endophthalmitis ist eine hämatogen fortgeleitete, bakterielle oder fungale Infektion, die über choroidale oder retinale Gefäße in den Augapfel eingeschwemmt wird [ 1 – 3 ]. Von dort infiltrieren die Keime in die Netzhaut, den …

Bakterielle endogene Endophthalmitis

Vitrektomie Leitthema

Eine endogene Endophthalmitis stellt einen ophthalmologischen Notfall dar, der umgehender Diagnostik und Therapie bedarf. Es sollte mit geeigneten Methoden, wie beispielsweise dem Freiburger Endophthalmitis-Set, ein Keimnachweis erfolgen. Bei der …

So erreichen Sie eine bestmögliche Wundheilung der Kornea

Die bestmögliche Wundheilung der Kornea, insbesondere ohne die Ausbildung von lichtstreuenden Narben, ist oberstes Gebot, um einer dauerhaften Schädigung der Hornhaut frühzeitig entgegenzuwirken und die Funktion des Auges zu erhalten.   

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.