Erschienen in:
01.04.2009 | Movement Disorders - Original Article
Globus pallidus internus firing rate modification after motor-imagination in three Parkinson’s disease patients
verfasst von:
Ramón Leiguarda, Daniel Cerquetti, Eduardo Tenca, Marcelo Merello
Erschienen in:
Journal of Neural Transmission
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Ausgabe 4/2009
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Abstract
Motor imagery is thought to involve the same processes of movement preparation as actual movement. Imagination of a simple repetitive movement significantly decreased the firing rate of extracellular micro recording at sensorimotor neurons of globus pallidus internus in three patients with Parkinson’s disease, who underwent microelectrode-guided posteroventral pallidotomy. These findings suggest, in agreement with previous clinical and functional neuroimaging studies that the motor corticostriatal circuit could be engaged in mental simulation.