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Breast Cancer
Erschienen in: Breast Cancer 4/2020

17.02.2020 | Original Article

Higher dietary total antioxidant capacity is not associated with risk of breast cancer in Iranian women

verfasst von: Maryam Safabakhsh, Hossein Imani, Sakineh Shab-Bidar

Erschienen in: Breast Cancer | Ausgabe 4/2020

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Abstract

Background

Our purpose was to assess the association between dietary total antioxidant capacity (DTAC), as assessed by oxygen radical absorbance capacity and breast cancer (BrCa) incidence among Iranian women.

Methods

This hospital-based case–control study included 150 newly diagnosed BrCa cases and 150 age-matched apparently healthy women from the Cancer Research Center, Imam Khomeini hospital, Iran. Socio-demographic data and anthropometric measures were determined. Dietary intake was assessed using a 147-item validated food frequency questionnaire. Energy-adjusted DTAC was calculated with the USDA database.

Results

After adjusting for potential confounders, multivariable logistic regression showed that the incidence of BrCa was not significantly different between highest tertile of DTAC and the lowest tertile (P trend = 0.91). Moreover, on the basis of menopausal status, no significant association between DTAC and BrCa risk among pre-menopausal (P trend = 0.62) and post-menopausal women (P trend = 0.77) was detected.

Conclusion

We did not observe any significant association of DTAC with BrCa incidence among Iranian women. Continued and expanded research on DTAC, evaluated by different methods and BrCa risk is needed to build the foundation for future progress in evidence-based public health efforts.
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Metadaten
Titel
Higher dietary total antioxidant capacity is not associated with risk of breast cancer in Iranian women
verfasst von
Maryam Safabakhsh
Hossein Imani
Sakineh Shab-Bidar
Publikationsdatum
17.02.2020
Verlag
Springer Japan
Erschienen in
Breast Cancer / Ausgabe 4/2020
Print ISSN: 1340-6868
Elektronische ISSN: 1880-4233
DOI
https://doi.org/10.1007/s12282-020-01059-2

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