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Current HIV/AIDS Reports
Erschienen in: Current HIV/AIDS Reports 1/2019

19.01.2019 | Central Nervous System and Cognition (SS Spudich, Section Editor)

HIV, Depression, and Cognitive Impairment in the Era of Effective Antiretroviral Therapy

verfasst von: Leah H. Rubin, Pauline M. Maki

Erschienen in: Current HIV/AIDS Reports | Ausgabe 1/2019

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Abstract

Purpose of Review

Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV−) individuals. We conducted a comprehensive review of the link between depression and cognition among PLWH.

Recent Findings

Studies examining depression and cognition in PLWH report high rates of current (median = 24%) and lifetime depression (42%). There is reliable evidence that depression is associated with overall CI among PLWH, and in the cognitive domains of processing speed, executive function, learning and memory, and motor function. Although few studies have examined the interaction between HIV serostatus and depression on CI, there is no evidence of a stronger association between CI and depression in PLWH compared with HIV− controls.

Summary

Depression is prevalent and reliably associated with CI in PLWH, with an overall pattern of domain-specific associations similar to that of HIV− individuals.
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Metadaten
Titel
HIV, Depression, and Cognitive Impairment in the Era of Effective Antiretroviral Therapy
verfasst von
Leah H. Rubin
Pauline M. Maki
Publikationsdatum
19.01.2019
Verlag
Springer US
Erschienen in
Current HIV/AIDS Reports / Ausgabe 1/2019
Print ISSN: 1548-3568
Elektronische ISSN: 1548-3576
DOI
https://doi.org/10.1007/s11904-019-00421-0

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The Science of Prevention (JD Stekler and JM Baeten, Section Editors)

HIV Prevention Interventions for Adolescents

Behavioral Bio-Medical Interface (JL Brown and RJ DiClemente, Section Editors)

Interventions to Reduce Drug Use Among Methamphetamine Users at Risk for HIV

Behavioral Bio-Medical Interface (JL Brown and RJ DiClemente, Section Editors)

Substance Use Screening in HIV Care Settings: a Review and Critique of the Literature

Behavioral Bio-Medical Interface (JL Brown and RJ DiClemente, Section Editors)

Substance Use and HIV Among Justice-Involved Youth: Intersecting Risks

The Science of Prevention (JD Stekler and JM Baeten, Section Editors)

The Impact of ACA and Medicaid Expansion on Progress Toward UNAIDS 90-90-90 Goals

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Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

25.04.2024 Allergien und Intoleranzreaktionen Nachrichten

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

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