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European Journal of Clinical Microbiology & Infectious Diseases

Erschienen in:

14.12.2017 | Original Article

Hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) from Pakistan: molecular characterisation by microarray technology

verfasst von: Bushra Jamil, Darius Gawlik, Muhammad Ali Syed, Asim Ali Shah, Shahid Ahmad Abbasi, Elke Müller, Annett Reißig, Ralf Ehricht, Stefan Monecke

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 4/2018

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Abstract

The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in Pakistan is known to be high, but very few studies have described the molecular epidemiology of the different MRSA clones circulating in the country. Forty-four MRSA isolates were collected from two tertiary care hospitals of the Rawalpindi district of Pakistan. All strains were identified by a conventional phenotypic method and then subjected to genotyping by microarray hybridisation. Six clonal complexes (CCs) and 19 strains were identified. The most commonly identified strains were: (i) Panton–Valentine leucocidin (PVL)-positive CC772-MRSA-V, “Bengal Bay Clone” (ten isolates; 22.3%), (ii) ST239-MRSA [III + ccrC] (five isolates) and (iii) a CC8-MRSA-IV strain, as well as CC6-MRSA-IV (both with four isolates; 9.1% each). Several of the strains detected indicated epidemiological links to the Middle Eastern/Arabian Gulf region. Further studies are needed to type MRSA from countries with less known epidemiology and to monitor the distribution and spread of strains, as well as possible links to global travel, migration and commerce.

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Titel: Hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) from Pakistan: molecular characterisation by microarray technology
verfasst von: Bushra Jamil
Darius Gawlik
Muhammad Ali Syed
Asim Ali Shah
Shahid Ahmad Abbasi
Elke Müller
Annett Reißig
Ralf Ehricht
Stefan Monecke
Publikationsdatum: 14.12.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 4/2018
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-017-3161-y

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