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21.01.2017 | Original Paper | Ausgabe 3/2018

AIDS and Behavior 3/2018

How Presentation of Drug Detection Results Changed Reports of Product Adherence in South Africa, Uganda and Zimbabwe

Zeitschrift:
AIDS and Behavior > Ausgabe 3/2018
Autoren:
Petina Musara, Elizabeth T. Montgomery, Nyaradzo M. Mgodi, Kubashni Woeber, Carolyne A. Akello, Miriam Hartmann, Helen Cheng, Lisa Levy, Ariana Katz, Cynthia I. Grossman, Z. Mike Chirenje, Ariane van der Straten, Barbara Mensch, On behalf of the Microbicide Trials Network-003D Study Team

Abstract

Accurate estimates of study product use are critical to understanding and addressing adherence challenges in HIV prevention trials. The VOICE trial exposed a significant gap between self-reported adherence and drug detection. The VOICE-D qualitative study was designed to better understand non-adherence during VOICE, and was conducted in 2 stages: before (stage 1) and after (stage 2) drug detection results were provided to participants. Transcripts from 44 women who participated in both stages were analysed to understand the effect of presenting drug detection data on narratives of product use. Thirty-six women reported high adherence in stage 1, yet admitted non-use in stage 2, three reported high adherence in both stages (contrary to their drug detection results) and five had consistent responses across both stages and drug results. Presenting objective measures of use may facilitate more accurate product use reporting and should be evaluated in future prevention trials.

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