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06.11.2019 | Original Research

How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion

verfasst von: Stefano Rausei, Federica Galli, Georgios Lianos, Fausto Rosa, Andrea Cossu, Alberto Biondi, Francesco Martignoni, Ferdinando Carlo Maria Cananzi, Uberto Fumagalli, Sergio Alfieri, Roberto Persiani, Vittorio Quagliuolo, Domenico D’Ugo, Riccardo Rosati

Erschienen in: Journal of Gastrointestinal Cancer | Ausgabe 3/2020

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Abstract

Aim

To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.

Patients and Methods

We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.

Results

Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.

Conclusion

We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.

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Titel: How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion
verfasst von: Stefano Rausei
Federica Galli
Georgios Lianos
Fausto Rosa
Andrea Cossu
Alberto Biondi
Francesco Martignoni
Ferdinando Carlo Maria Cananzi
Uberto Fumagalli
Sergio Alfieri
Roberto Persiani
Vittorio Quagliuolo
Domenico D’Ugo
Riccardo Rosati
Publikationsdatum: 06.11.2019
Verlag: Springer US
Erschienen in: Journal of Gastrointestinal Cancer / Ausgabe 3/2020
Print ISSN: 1941-6628
Elektronische ISSN: 1941-6636
DOI: https://doi.org/10.1007/s12029-019-00321-x

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How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion

Abstract